Anti-Cancer Drug Validation: the Contribution of Tissue Engineered Models
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Anti-Cancer Drug Validation: the Contribution of Tissue Engineered Models
Authors
Keywords
Cancer, Tissue engineering, Biomaterials, 3D, Drug discovery
Journal
Stem Cell Reviews and Reports
Volume 13, Issue 3, Pages 347-363
Publisher
Springer Nature
Online
2017-02-24
DOI
10.1007/s12015-017-9720-x
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Drug cytotoxicity and signaling pathway analysis with three-dimensional tumor spheroids in a microwell-based microfluidic chip for drug screening
- (2015) Yongli Chen et al. ANALYTICA CHIMICA ACTA
- 3D tissue-engineered bone marrow as a novel model to study pathophysiology and drug resistance in multiple myeloma
- (2015) Pilar de la Puente et al. BIOMATERIALS
- Deconstructing the role of the ECM microenvironment on drug efficacy targeting MAPK signaling in a pre-clinical platform for cutaneous melanoma
- (2015) Benjamin H. Blehm et al. BIOMATERIALS
- Bioreactor-engineered cancer tissue-like structures mimic phenotypes, gene expression profiles and drug resistance patterns observed “in vivo”
- (2015) Christian Hirt et al. BIOMATERIALS
- Formation of stable small cell number three-dimensional ovarian cancer spheroids using hanging drop arrays for preclinical drug sensitivity assays
- (2015) Shreya Raghavan et al. GYNECOLOGIC ONCOLOGY
- 3D in vitro modeling of the central nervous system
- (2015) Amy M. Hopkins et al. PROGRESS IN NEUROBIOLOGY
- Evaluating Biomaterial- and Microfluidic-Based 3D Tumor Models
- (2015) Mariana R. Carvalho et al. TRENDS IN BIOTECHNOLOGY
- p21-Activated Kinase 1 Coordinates Aberrant Cell Survival and Pericellular Proteolysis in a Three-Dimensional Culture Model for Premalignant Progression of Human Breast Cancer
- (2015) Quanwen Li et al. NEOPLASIA
- Bioengineering 3D environments for cancer models
- (2014) Mireia Alemany-Ribes et al. ADVANCED DRUG DELIVERY REVIEWS
- 3D high-content screening for the identification of compounds that target cells in dormant tumor spheroid regions
- (2014) Carsten Wenzel et al. EXPERIMENTAL CELL RESEARCH
- Current standing and future prospects for the technologies proposed to transform toxicity testing in the 21st century
- (2014) Erwin van Vliet ALTEX-Alternatives to Animal Experimentation
- A bioengineered 3D ovarian cancer model for the assessment of peptidase–mediated enhancement of spheroid growth and intraperitoneal spread
- (2013) Daniela Loessner et al. BIOMATERIALS
- Application of a microfluidic chip-based 3D co-culture to test drug sensitivity for individualized treatment of lung cancer
- (2013) Zhiyun Xu et al. BIOMATERIALS
- A short-term colorectal cancer sphere culture as a relevant tool for human cancer biology investigation
- (2013) L-B Weiswald et al. BRITISH JOURNAL OF CANCER
- Three-dimensionally engineered biomimetic tissue models forin vitrodrug evaluation: delivery, efficacy and toxicity
- (2013) Yvonne Peck et al. Expert Opinion on Drug Delivery
- Considerations on the development of a model of kidney bioengineering and regeneration in rats
- (2013) Andrea Peloso et al. Expert Review of Medical Devices
- Establishment of a human 3D lung cancer model based on a biological tissue matrix combined with a Boolean in silico model
- (2013) Anna T. Stratmann et al. Molecular Oncology
- Regeneration and experimental orthotopic transplantation of a bioengineered kidney
- (2013) Jeremy J Song et al. NATURE MEDICINE
- Development of a High-Throughput Three-Dimensional Invasion Assay for Anti-Cancer Drug Discovery
- (2013) Nikki A. Evensen et al. PLoS One
- Correction: Bioengineered 3D Human Kidney Tissue, a Platform for the Determination of Nephrotoxicity
- (2013) Teresa M. DesRochers et al. PLoS One
- Spheroid culture as a tool for creating 3D complex tissues
- (2013) Eelco Fennema et al. TRENDS IN BIOTECHNOLOGY
- Development of a human three-dimensional organotypic skin-melanoma spheroid model for in vitro drug testing
- (2013) H Vörsmann et al. Cell Death & Disease
- Upcoming strategies for the treatment of metastatic melanoma
- (2012) Francesco Spagnolo et al. ARCHIVES OF DERMATOLOGICAL RESEARCH
- A 3-D organoid kidney culture model engineered for high-throughput nephrotoxicity assays
- (2012) Anna I. Astashkina et al. BIOMATERIALS
- Synthetic 3D multicellular systems for drug development
- (2012) Markus Rimann et al. CURRENT OPINION IN BIOTECHNOLOGY
- Opportunities and challenges for use of tumor spheroids as models to test drug delivery and efficacy
- (2012) Geeta Mehta et al. JOURNAL OF CONTROLLED RELEASE
- Engineering therapies in the CNS: What works and what can be translated
- (2012) Andrew J. Shoffstall et al. NEUROSCIENCE LETTERS
- 3D Porous Chitosan-Alginate Scaffolds: A New Matrix for Studying Prostate Cancer Cell-Lymphocyte Interactions In Vitro
- (2012) Stephen J. Florczyk et al. Advanced Healthcare Materials
- Skin tissue engineering — In vivo and in vitro applications
- (2011) Florian Groeber et al. ADVANCED DRUG DELIVERY REVIEWS
- Modeling Colon Adenocarcinomas in Vitro
- (2011) Helmut Dolznig et al. AMERICAN JOURNAL OF PATHOLOGY
- Elucidating the mechanobiology of malignant brain tumors using a brain matrix-mimetic hyaluronic acid hydrogel platform
- (2011) Badriprasad Ananthanarayanan et al. BIOMATERIALS
- 3D in vitro bioengineered tumors based on collagen I hydrogels
- (2011) Christopher S. Szot et al. BIOMATERIALS
- Determining tamoxifen sensitivity using primary breast cancer tissue in collagen-based three-dimensional culture
- (2011) Alexander D. Leeper et al. BIOMATERIALS
- Three-dimensional cancer-bone metastasis model using ex-vivo co-cultures of live calvarial bones and cancer cells
- (2011) Paul Curtin et al. BIOMATERIALS
- Co-culture of stromal and erythroleukemia cells in a perfused hollow fiber bioreactor system as an in vitro bone marrow model for myeloid leukemia
- (2011) Suaidah Binte Mohamed Usuludin et al. BIOTECHNOLOGY AND BIOENGINEERING
- Drug localization in different lung cancer phenotypes by MALDI mass spectrometry imaging
- (2011) György Marko-Varga et al. Journal of Proteomics
- Generation of oxygen gradients in microfluidic devices for cell culture using spatially confined chemical reactions
- (2011) Yung-Ann Chen et al. LAB ON A CHIP
- High drug attrition rates—where are we going wrong?
- (2011) Lisa Hutchinson et al. Nature Reviews Clinical Oncology
- Melanoma Spheroids Grown Under Neural Crest Cell Conditions Are Highly Plastic Migratory/Invasive Tumor Cells Endowed with Immunomodulator Function
- (2011) Kiran Ramgolam et al. PLoS One
- Radioresistance of human glioma spheroids and expression of HSP70, p53 and EGFr
- (2011) Carlos A Fedrigo et al. Radiation Oncology
- Alginate based 3D hydrogels as an in vitro co-culture model platform for the toxicity screening of new chemical entities
- (2011) Shih-Feng Lan et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- The bone marrow microenvironment and leukemia: biology and therapeutic targeting
- (2011) Edward Allan R Sison et al. Expert Review of Hematology
- 3D tumour models: novel in vitro approaches to cancer studies
- (2011) Agata Nyga et al. Journal of Cell Communication and Signaling
- Regenerative medicine of the kidney
- (2010) Laura Perin et al. ADVANCED DRUG DELIVERY REVIEWS
- High-throughput 3D spheroid culture and drug testing using a 384 hanging drop array
- (2010) Yi-Chung Tung et al. ANALYST
- Bioengineered 3D platform to explore cell–ECM interactions and drug resistance of epithelial ovarian cancer cells
- (2010) Daniela Loessner et al. BIOMATERIALS
- Carvedilol in glioma treatment alone and with imatinib in vitro
- (2010) Erguven INTERNATIONAL JOURNAL OF ONCOLOGY
- A Review of Three-Dimensional In Vitro Tissue Models for Drug Discovery and Transport Studies
- (2010) Nelita T. Elliott et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Invasive three-dimensional organotypic neoplasia from multiple normal human epithelia
- (2010) Todd W Ridky et al. NATURE MEDICINE
- Reconstituting Organ-Level Lung Functions on a Chip
- (2010) D. Huh et al. SCIENCE
- Ectopic Human Mesenchymal Stem Cell-Coated Scaffolds in NOD/SCID Mice: An In Vivo Model of the Leukemia Niche
- (2010) Sarah R. Vaiselbuh et al. TISSUE ENGINEERING PART C-METHODS
- Hyaluronic acid-based hydrogels as 3D matrices for in vitro evaluation of chemotherapeutic drugs using poorly adherent prostate cancer cells
- (2009) Lisa A. Gurski et al. BIOMATERIALS
- The development of a three-dimensional scaffold for ex vivo biomimicry of human acute myeloid leukaemia
- (2009) Teresa Mortera Blanco et al. BIOMATERIALS
- Newly characterised ex vivo colospheres as a three-dimensional colon cancer cell model of tumour aggressiveness
- (2009) L-B Weiswald et al. BRITISH JOURNAL OF CANCER
- Three-dimensionalin vitrocell biology models of ovarian and endometrial cancer
- (2009) B. Grun et al. CELL PROLIFERATION
- Elastin-derived peptides: Matrikines critical for glioblastoma cell aggressiveness in a 3-D system
- (2009) Bérénice Coquerel et al. GLIA
- Multicellular spheroids in ovarian cancer metastases: Biology and pathology
- (2009) Kristy Shield et al. GYNECOLOGIC ONCOLOGY
- Three-Dimensional Overlay Culture Models of Human Breast Cancer Reveal a Critical Sensitivity to Mitogen-Activated Protein Kinase Kinase Inhibitors
- (2009) Q. Li et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Involvement of Rac and Rho signaling in cancer cell motility in 3D substrates
- (2009) D Yamazaki et al. ONCOGENE
- Fibroblast-derived 3D matrix differentially regulates the growth and drug-responsiveness of human cancer cells
- (2008) Ilya Serebriiskii et al. MATRIX BIOLOGY
- 3-D Tumor Model forIn VitroEvaluation of Anticancer Drugs
- (2008) Jayme L. Horning et al. MOLECULAR PHARMACEUTICS
- New dimensions in tumor immunology: what does 3D culture reveal?
- (2008) Chantal Feder-Mengus et al. TRENDS IN MOLECULAR MEDICINE
- Hyaluronan hydrogel: An appropriate three-dimensional model for evaluation of anticancer drug sensitivity
- (2007) Laurent David et al. Acta Biomaterialia
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started