Impaired Hippocampal Glutamate and Glutamine Metabolism in the db/db Mouse Model of Type 2 Diabetes Mellitus

Specificity of exogenous acetate and glutamate as astrocyte substrates examined in acute brain slices from female mice using methionine sulfoximine (MSO) to inhibit glutamine synthesis

(2017) Jens Velde Andersen et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Survey of Institutional Policies for Provision of “CMV-Safe” Blood in Ontario

(2016) Laura Finlay et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Improved cerebral energetics and ketone body metabolism in db/db mice

(2016) Jens V Andersen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Mitochondrial dysfunction precedes depression of AMPK/AKT signaling in insulin resistance induced by high glucose in primary cortical neurons

(2016) Yunhua Peng et al.   JOURNAL OF NEUROCHEMISTRY

Glutamate oxidation in astrocytes: Roles of glutamate dehydrogenase and aminotransferases

(2016) Mary C. McKenna et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Alterations in Cerebral Cortical Glucose and Glutamine Metabolism Precedes Amyloid Plaques in the APPswe/PSEN1dE9 Mouse Model of Alzheimer’s Disease

(2016) Jens V. Andersen et al.   NEUROCHEMICAL RESEARCH

Metabolic Characterization of Acutely Isolated Hippocampal and Cerebral Cortical Slices Using [U-13C]Glucose and [1,2-13C]Acetate as Substrates

(2016) Laura F. McNair et al.   NEUROCHEMICAL RESEARCH

Metabonomic profiles delineate potential role of glutamate-glutamine cycle in db/db mice with diabetes-associated cognitive decline

(2016) Yongquan Zheng et al.   Molecular Brain

Dysfunctional TCA-Cycle Metabolism in Glutamate Dehydrogenase Deficient Astrocytes

(2015) Jakob D. Nissen et al.   GLIA

Hippocampal insulin resistance and cognitive dysfunction

(2015) Geert Jan Biessels et al.   NATURE REVIEWS NEUROSCIENCE

Drp1-Mediated Mitochondrial Abnormalities Link to Synaptic Injury in Diabetes Model

(2014) Shengbin Huang et al.   DIABETES

Glutamate synthesis has to be matched by its degradation - where do all the carbons go?

(2014) Ursula Sonnewald   JOURNAL OF NEUROCHEMISTRY

Glucose Levels and Risk of Dementia

(2013) Paul K. Crane et al.   NEW ENGLAND JOURNAL OF MEDICINE

Differential central pathology and cognitive impairment in pre-diabetic and diabetic mice

(2013) Juan Jose Ramos-Rodriguez et al.   PSYCHONEUROENDOCRINOLOGY

Diabetes mellitus and risk of dementia: A meta-analysis of prospective observational studies

(2013) Kapil Gudala et al.   Journal of Diabetes Investigation

Diabetic db/db mice exhibit central nervous system and peripheral molecular alterations as seen in neurological disorders

(2013) A Ernst et al.   Translational Psychiatry

Glutamate Pays Its Own Way in Astrocytes

(2013) Mary C. McKenna   Frontiers in Endocrinology

Central nervous system endoplasmic reticulum stress in a murine model of type 2 diabetes

(2012) C. Sims-Robinson et al.   DIABETOLOGIA

Insulin Resistance and Alzheimer-like Reductions in Regional Cerebral Glucose Metabolism for Cognitively Normal Adults With Prediabetes or Early Type 2 Diabetes

(2010) Laura D. Baker et al.   ARCHIVES OF NEUROLOGY

Obesity and Type 2 Diabetes in Rats are Associated with Altered Brain Glycogen and Amino-Acid Homeostasis

(2010) Helle M Sickmann et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Functional Importance of the Astrocytic Glycogen-Shunt and Glycolysis for Maintenance of an Intact Intra/Extracellular Glutamate Gradient

(2010) Arne Schousboe et al.   NEUROTOXICITY RESEARCH

Diabetes impairs hippocampal function through glucocorticoid-mediated effects on new and mature neurons

(2008) Alexis M Stranahan et al.   NATURE NEUROSCIENCE