Thymosin-α1 expands deficient IL-10-producing regulatory B cell subsets in relapsing–remitting multiple sclerosis patients

Serum thymosin α 1 levels in patients with chronic inflammatory autoimmune diseases

(2016) F. Pica et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Interferon-β therapy specifically reduces pathogenic memory B cells in multiple sclerosis patients by inducing a FAS-mediated apoptosis

(2016) Fabiana Rizzo et al.   IMMUNOLOGY AND CELL BIOLOGY

Thymosin beta4 promotes oligodendrogenesis in the demyelinating central nervous system

(2016) Jing Zhang et al.   NEUROBIOLOGY OF DISEASE

IL-10-produced by human transitional B-cells down-regulates CD86 expression on B-cells leading to inhibition of CD4+T-cell responses

(2016) Estefania Nova-Lamperti et al.   Scientific Reports

Dual effect of Thymosin α 1 on human monocyte-derived dendritic cellin vitrostimulated with viral and bacterial toll-like receptor agonists

(2015) Elena Giacomini et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

The expanding family of regulatory B cells

(2015) Claudia Mauri et al.   INTERNATIONAL IMMUNOLOGY

IFN-β Therapy Regulates TLR7-Mediated Response in Plasmacytoid Dendritic Cells of Multiple Sclerosis Patients Influencing an Anti-Inflammatory Status

(2015) Martina Severa et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Role of the innate and adaptive immune responses in the course of multiple sclerosis

(2015) Bernhard Hemmer et al.   LANCET NEUROLOGY

Proinflammatory GM-CSF–producing B cells in multiple sclerosis and B cell depletion therapy

(2015) Rui Li et al.   Science Translational Medicine

Unaltered regulatory B-cell frequency and function in patients with multiple sclerosis

(2014) Laure Michel et al.   CLINICAL IMMUNOLOGY

Interleukin-10-Producing Plasmablasts Exert Regulatory Function in Autoimmune Inflammation

(2014) Masanori Matsumoto et al.   IMMUNITY

IFN-β therapy modulates B-cell and monocyte crosstalk via TLR7 in multiple sclerosis patients

(2013) Elena Giacomini et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

CD19+CD24hiCD38hi B Cells Maintain Regulatory T Cells While Limiting TH1 and TH17 Differentiation

(2013) F. Flores-Borja et al.   Science Translational Medicine

Jack of all trades: thymosin α1 and its pleiotropy

(2012) Luigina Romani et al.   Annals of the New York Academy of Sciences

B cells and antibodies in multiple sclerosis pathogenesis and therapy

(2012) Markus Krumbholz et al.   Nature Reviews Neurology

Interleukin-10 produced by B cells is crucial for the suppression of Th17/Th1 responses, induction of T regulatory type 1 cells and reduction of collagen-induced arthritis

(2012) Natalie A Carter et al.   ARTHRITIS RESEARCH & THERAPY

Effect of thymosin alpha-1 on subpopulations of Th1, Th2, Th17, and regulatory T cells (Tregs) in vitro

(2011) Xia Yang et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Treatment of multiple sclerosis with Anti-CD20 antibodies

(2011) Barbara Barun et al.   CLINICAL IMMUNOLOGY

B cells in multiple sclerosis: connecting the dots

(2011) H-Christian von Büdingen et al.   CURRENT OPINION IN IMMUNOLOGY

Reduction in IL-10 producing B cells (Breg) in multiple sclerosis is accompanied by a reduced naïve/memory Breg ratio during a relapse but not in remission

(2011) Stephanie Knippenberg et al.   JOURNAL OF NEUROIMMUNOLOGY

Transcription profile of human lymphocytes following in vitro treatment with thymosin alpha-1

(2010) Claudia Matteucci et al.   Annals of the New York Academy of Sciences

Immunological modifications during treatment with thymosin α1 plus antiviral therapy in chronic hepatitis C

(2010) E. Grandini et al.   Annals of the New York Academy of Sciences

Modulation of B cell responses by Toll-like receptors

(2010) Jayaum Booth et al.   CELL AND TISSUE RESEARCH

CD19+CD24hiCD38hi B Cells Exhibit Regulatory Capacity in Healthy Individuals but Are Functionally Impaired in Systemic Lupus Erythematosus Patients

(2010) Paul A. Blair et al.   IMMUNITY

Polymorphisms of innate pattern recognition receptors, response to interferon-beta and development of neutralizing antibodies in multiple sclerosis patients

(2010) Christian Enevold et al.   Multiple Sclerosis Journal

Abnormal B-cell cytokine responses a trigger of T-cell-mediated disease in MS?

(2009) Amit Bar-Or et al.   ANNALS OF NEUROLOGY

B7-1/2 (CD80/CD86) Direct Signaling to B Cells Enhances IgG Secretion

(2009) F. C. Rau et al.   JOURNAL OF IMMUNOLOGY

Neurological functional recovery after thymosin beta4 treatment in mice with experimental auto encephalomyelitis

(2009) J. Zhang et al.   NEUROSCIENCE