The expanding family of regulatory B cells

TIM-1 Signaling Is Required for Maintenance and Induction of Regulatory B Cells

(2015) M. Y. Yeung et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Transitional B Lymphocytes Are Associated With Protection From Kidney Allograft Rejection: A Prospective Study

(2015) S. Shabir et al.   AMERICAN JOURNAL OF TRANSPLANTATION

B-Cells induce regulatory T cells through TGF-β/IDO production in A CTLA-4 dependent manner

(2015) A. Nouël et al.   JOURNAL OF AUTOIMMUNITY

Tim-1 Is Essential for Induction and Maintenance of IL-10 in Regulatory B Cells and Their Regulation of Tissue Inflammation

(2015) Sheng Xiao et al.   JOURNAL OF IMMUNOLOGY

IFN-β Treatment Requires B Cells for Efficacy in Neuroautoimmunity

(2015) Ryan D. Schubert et al.   JOURNAL OF IMMUNOLOGY

Immunosuppressive plasma cells impede T-cell-dependent immunogenic chemotherapy

(2015) Shabnam Shalapour et al.   NATURE

PD-L1hi B cells are critical regulators of humoral immunity

(2015) Adnan R. Khan et al.   Nature Communications

Regulatory B cells are enriched within the IgM memory and transitional subsets in healthy donors but are deficient in chronic GVHD

(2014) A. Khoder et al.   BLOOD

Transitional-2 B cells acquire regulatory function during tolerance induction and contribute to allograft survival

(2014) Aurélie Moreau et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Interleukin-10-Producing Plasmablasts Exert Regulatory Function in Autoimmune Inflammation

(2014) Masanori Matsumoto et al.   IMMUNITY

A Novel Mechanism of B Cell–Mediated Immune Suppression through CD73 Expression and Adenosine Production

(2014) Hiroaki Kaku et al.   JOURNAL OF IMMUNOLOGY

Immunologic Human Renal Allograft Injury Associates with an Altered IL-10/TNF-  Expression Ratio in Regulatory B Cells

(2014) A. Cherukuri et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases

(2014) Ping Shen et al.   NATURE

Regulatory B cells are induced by gut microbiota–driven interleukin-1β and interleukin-6 production

(2014) Elizabeth C Rosser et al.   NATURE MEDICINE

Interleukin-35 induces regulatory B cells that suppress autoimmune disease

(2014) Ren-Xi Wang et al.   NATURE MEDICINE

IL-10-Producing B Cells Are Induced Early in HIV-1 Infection and Suppress HIV-1-Specific T Cell Responses

(2014) Jun Liu et al.   PLoS One

Regulatory B Cells Inhibit Cytotoxic T Lymphocyte (CTL) Activity and Elimination of Infected CD4 T Cells after In Vitro Reactivation of HIV Latent Reservoirs

(2014) Basile Siewe et al.   PLoS One

Regulatory B Cells: An Exciting Target for Future Therapeutics in Transplantation

(2014) Alexandre Nouël et al.   Frontiers in Immunology

Adenosine production by human B cells and B cell-mediated suppression of activated T cells

(2013) Z. Saze et al.   BLOOD

Interleukin 21-Induced Granzyme B-Expressing B Cells Infiltrate Tumors and Regulate T Cells

(2013) S. Lindner et al.   CANCER RESEARCH

IgG4 production is confined to human IL-10–producing regulatory B cells that suppress antigen-specific immune responses

(2013) Willem van de Veen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Regulatory B cell frequency correlates with markers of HIV disease progression and attenuates anti-HIV CD8+ T cell function in vitro

(2013) Basile Siewe et al.   JOURNAL OF LEUKOCYTE BIOLOGY

CD19+CD24hiCD38hi B Cells Maintain Regulatory T Cells While Limiting TH1 and TH17 Differentiation

(2013) F. Flores-Borja et al.   Science Translational Medicine

IL-10-producing regulatory B cells (B10 cells) in autoimmune disease

(2013) Ioannis Kalampokis et al.   ARTHRITIS RESEARCH & THERAPY

IL-10–Producing Regulatory B10 Cells Ameliorate Collagen-Induced Arthritis via Suppressing Th17 Cell Generation

(2012) Min Yang et al.   AMERICAN JOURNAL OF PATHOLOGY

Immune Regulatory Function of B Cells

(2012) Claudia Mauri et al.   Annual Review of Immunology

Lipid-Antigen Presentation by CD1d+ B Cells Is Essential for the Maintenance of Invariant Natural Killer T Cells

(2012) Anneleen Bosma et al.   IMMUNITY

Marginal Zone B Cells Regulate Antigen-Specific T Cell Responses during Infection

(2012) R. Bankoti et al.   JOURNAL OF IMMUNOLOGY

Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions

(2012) Ayumi Yoshizaki et al.   NATURE

Defect in regulatory B-cell function and development of systemic autoimmunity in T-cell Ig mucin 1 (Tim-1) mucin domain-mutant mice

(2012) Sheng Xiao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interleukin-10 produced by B cells is crucial for the suppression of Th17/Th1 responses, induction of T regulatory type 1 cells and reduction of collagen-induced arthritis

(2012) Natalie A Carter et al.   ARTHRITIS RESEARCH & THERAPY

IL-10–Producing Regulatory B10 Cells Inhibit Intestinal Injury in a Mouse Model

(2011) Koichi Yanaba et al.   AMERICAN JOURNAL OF PATHOLOGY

Regulatory B cells are identified by expression of TIM-1 and can be induced through TIM-1 ligation to promote tolerance in mice

(2011) Qing Ding et al.   JOURNAL OF CLINICAL INVESTIGATION

Mice Lacking Endogenous IL-10-Producing Regulatory B Cells Develop Exacerbated Disease and Present with an Increased Frequency of Th1/Th17 but a Decrease in Regulatory T Cells

(2011) N. A. Carter et al.   JOURNAL OF IMMUNOLOGY

Regulatory B10 Cells Differentiate into Antibody-Secreting Cells After Transient IL-10 Production In Vivo

(2011) D. Maseda et al.   JOURNAL OF IMMUNOLOGY

B regulatory cells and the tumor-promoting actions of TNF-  during squamous carcinogenesis

(2011) T. Schioppa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells

(2010) Y. Iwata et al.   BLOOD

CD19+CD24hiCD38hi B Cells Exhibit Regulatory Capacity in Healthy Individuals but Are Functionally Impaired in Systemic Lupus Erythematosus Patients

(2010) Paul A. Blair et al.   IMMUNITY

Regulatory B cells prevent and reverse allergic airway inflammation via FoxP3-positive T regulatory cells in a murine model

(2010) Sylvie Amu et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Identification of a B cell signature associated with renal transplant tolerance in humans

(2010) Kenneth A. Newell et al.   JOURNAL OF CLINICAL INVESTIGATION

TLR-2-Activated B Cells Suppress Helicobacter-Induced Preneoplastic Gastric Immunopathology by Inducing T Regulatory-1 Cells

(2010) A. Sayi et al.   JOURNAL OF IMMUNOLOGY

Regulatory B Cells (B10 Cells) Have a Suppressive Role in Murine Lupus: CD19 and B10 Cell Deficiency Exacerbates Systemic Autoimmunity

(2010) R. Watanabe et al.   JOURNAL OF IMMUNOLOGY

Novel Human Transitional B Cell Populations Revealed by B Cell Depletion Therapy

(2009) Arumugam Palanichamy et al.   JOURNAL OF IMMUNOLOGY

The Development and Function of Regulatory B Cells Expressing IL-10 (B10 Cells) Requires Antigen Receptor Diversity and TLR Signals

(2009) K. Yanaba et al.   JOURNAL OF IMMUNOLOGY

Selective Targeting of B Cells with Agonistic Anti-CD40 Is an Efficacious Strategy for the Generation of Induced Regulatory T2-Like B Cells and for the Suppression of Lupus in MRL/lpr Mice

(2009) P. A. Blair et al.   JOURNAL OF IMMUNOLOGY

A granulocyte-macrophage colony–stimulating factor and interleukin-15 fusokine induces a regulatory B cell population with immune suppressive properties

(2009) Moutih Rafei et al.   NATURE MEDICINE

Reduced Fas ligand-expressing splenic CD5+ B lymphocytes in severe collagen-induced arthritis

(2009) Steven K Lundy et al.   ARTHRITIS RESEARCH & THERAPY

Helminth infections associated with multiple sclerosis induce regulatory B cells

(2008) Jorge Correale et al.   ANNALS OF NEUROLOGY

A Regulatory B Cell Subset with a Unique CD1dhiCD5+ Phenotype Controls T Cell-Dependent Inflammatory Responses

(2008) Koichi Yanaba et al.   IMMUNITY

Regulatory role of B-1 B cells in chronic colitis

(2008) Y. Shimomura et al.   INTERNATIONAL IMMUNOLOGY

Regulatory B cells inhibit EAE initiation in mice while other B cells promote disease progression

(2008) Takashi Matsushita et al.   JOURNAL OF CLINICAL INVESTIGATION