IL-10-produced by human transitional B-cells down-regulates CD86 expression on B-cells leading to inhibition of CD4+T-cell responses

Transitional B Lymphocytes Are Associated With Protection From Kidney Allograft Rejection: A Prospective Study

(2015) S. Shabir et al.   AMERICAN JOURNAL OF TRANSPLANTATION

CD19+CD24hiCD38hiBregs involved in downregulate helper T cells and upregulate regulatory T cells in gastric cancer

(2015) Weiwei Wang et al.   Oncotarget

Diversity of gut microflora is required for the generation of B cell with regulatory properties in a skin graft model

(2015) R. Alhabbab et al.   Scientific Reports

Regulatory B cells are enriched within the IgM memory and transitional subsets in healthy donors but are deficient in chronic GVHD

(2014) A. Khoder et al.   BLOOD

Donor and host B cell-derived IL-10 contributes to suppression of graft-versus-host disease

(2014) Michael Weber et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Immunologic Human Renal Allograft Injury Associates with an Altered IL-10/TNF-  Expression Ratio in Regulatory B Cells

(2014) A. Cherukuri et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

CD19+CD24hiCD38hi B Cells Maintain Regulatory T Cells While Limiting TH1 and TH17 Differentiation

(2013) F. Flores-Borja et al.   Science Translational Medicine

Anti-CD45RB/Anti-TIM-1-Induced Tolerance Requires Regulatory B Cells

(2012) K. M. Lee et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Immune Regulatory Function of B Cells

(2012) Claudia Mauri et al.   Annual Review of Immunology

Unknown

(2012) Hernandez Silva et al.   MOLECULAR MEDICINE

Regulatory B cells are identified by expression of TIM-1 and can be induced through TIM-1 ligation to promote tolerance in mice

(2011) Qing Ding et al.   JOURNAL OF CLINICAL INVESTIGATION

Ubiquitination of CD86 Is a Key Mechanism in Regulating Antigen Presentation by Dendritic Cells

(2011) G. Baravalle et al.   JOURNAL OF IMMUNOLOGY

Trans-Endocytosis of CD80 and CD86: A Molecular Basis for the Cell-Extrinsic Function of CTLA-4

(2011) O. S. Qureshi et al.   SCIENCE

Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells

(2010) Y. Iwata et al.   BLOOD

CD19+CD24hiCD38hi B Cells Exhibit Regulatory Capacity in Healthy Individuals but Are Functionally Impaired in Systemic Lupus Erythematosus Patients

(2010) Paul A. Blair et al.   IMMUNITY

Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans

(2010) Pervinder Sagoo et al.   JOURNAL OF CLINICAL INVESTIGATION

Identification of a B cell signature associated with renal transplant tolerance in humans

(2010) Kenneth A. Newell et al.   JOURNAL OF CLINICAL INVESTIGATION

Regulatory B Cells (B10 Cells) Have a Suppressive Role in Murine Lupus: CD19 and B10 Cell Deficiency Exacerbates Systemic Autoimmunity

(2010) R. Watanabe et al.   JOURNAL OF IMMUNOLOGY

Novel Human Transitional B Cell Populations Revealed by B Cell Depletion Therapy

(2009) Arumugam Palanichamy et al.   JOURNAL OF IMMUNOLOGY

Selective Targeting of B Cells with Agonistic Anti-CD40 Is an Efficacious Strategy for the Generation of Induced Regulatory T2-Like B Cells and for the Suppression of Lupus in MRL/lpr Mice

(2009) P. A. Blair et al.   JOURNAL OF IMMUNOLOGY