Somatic Mutations and Splicing Variants of Focal Adhesion Kinase in Non–Small Cell Lung Cancer

Molecular Pathways: Endothelial Cell FAK--A Target for Cancer Treatment

(2016) M. Roy-Luzarraga et al.   CLINICAL CANCER RESEARCH

Targeting focal adhesion kinase renders pancreatic cancers responsive to checkpoint immunotherapy

(2016) Hong Jiang et al.   NATURE MEDICINE

Focal Adhesion Kinase Inhibitors in Combination with Erlotinib Demonstrate Enhanced Anti-Tumor Activity in Non-Small Cell Lung Cancer

(2016) Grant A. Howe et al.   PLoS One

Development of RNA-FISH Assay for Detection of Oncogenic FGFR3-TACC3 Fusion Genes in FFPE Samples

(2016) Masahiro Kurobe et al.   PLoS One

Global cancer statistics, 2012

(2015) Lindsey A. Torre et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Alternative transcription initiation leads to expression of a novel ALK isoform in cancer

(2015) Thomas Wiesner et al.   NATURE

Identification of recurrent regulated alternative splicing events across human solid tumors

(2015) Miri Danan-Gotthold et al.   NUCLEIC ACIDS RESEARCH

TCGASpliceSeq a compendium of alternative mRNA splicing in cancer

(2015) Michael Ryan et al.   NUCLEIC ACIDS RESEARCH

FAK signaling in human cancer as a target for therapeutics

(2015) Brian Y. Lee et al.   PHARMACOLOGY & THERAPEUTICS

Expression of pY397 FAK promotes the development of non-small cell lung cancer

(2015) BAICHUN WANG et al.   Oncology Letters

The chemokine CXCL13 in lung cancers associated with environmental polycyclic aromatic hydrocarbons pollution

(2015) Gui-Zhen Wang et al.   eLife

Characterization of Somatic Mutations in Air Pollution-Related Lung Cancer

(2015) Xian-Jun Yu et al.   EBioMedicine

Targeting FAK in human cancer: from finding to first clinical trials

(2014) Vita Golubovskaya   Frontiers in Bioscience-Landmark

Understanding the Roles of FAK in Cancer

(2014) Hyunho Yoon et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

An aberrant spliced transcript of focal adhesion kinase is exclusively expressed in human breast cancer

(2014) Ling Yao et al.   Journal of Translational Medicine

The landscape and therapeutic relevance of cancer-associated transcript fusions

(2014) K Yoshihara et al.   ONCOGENE

Merlin Deficiency Predicts FAK Inhibitor Sensitivity: A Synthetic Lethal Relationship

(2014) I. M. Shapiro et al.   Science Translational Medicine

Tumor-Specific Isoform Switch of the Fibroblast Growth Factor Receptor 2 Underlies the Mesenchymal and Malignant Phenotypes of Clear Cell Renal Cell Carcinomas

(2013) Q. Zhao et al.   CLINICAL CANCER RESEARCH

Role of Focal Adhesion Kinase in Regulating YB–1–Mediated Paclitaxel Resistance in Ovarian Cancer

(2013) Yu Kang et al.   JNCI-Journal of the National Cancer Institute

IGFBP2/FAK Pathway Is Causally Associated with Dasatinib Resistance in Non-Small Cell Lung Cancer Cells

(2013) H. Lu et al.   MOLECULAR CANCER THERAPEUTICS

RHOA-FAK Is a Required Signaling Axis for the Maintenance of KRAS-Driven Lung Adenocarcinomas

(2013) Georgia Konstantinidou et al.   Cancer Discovery

Genomic Landscape of Non-Small Cell Lung Cancer in Smokers and Never-Smokers

(2012) Ramaswamy Govindan et al.   CELL

Lung carcinogenesis by tobacco smoke

(2012) Stephen S. Hecht   INTERNATIONAL JOURNAL OF CANCER

Overexpression of focal adhesion kinase correlates with increased lymph node metastasis and poor prognosis in non-small-cell lung cancer

(2012) Hong-Fei Ji et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Safety, Pharmacokinetic, and Pharmacodynamic Phase I Dose-Escalation Trial of PF-00562271, an Inhibitor of Focal Adhesion Kinase, in Advanced Solid Tumors

(2012) Jeffrey R. Infante et al.   JOURNAL OF CLINICAL ONCOLOGY

Focal Adhesion Kinase Splice Variants Maintain Primitive Acute Myeloid Leukemia Cells Through Altered Wnt Signaling

(2012) Mathieu Despeaux et al.   STEM CELLS

NNK promotes migration and invasion of lung cancer cells through activation of c-Src/PKCι/FAK loop

(2011) Jie Shen et al.   CANCER LETTERS

Global Profiling and Molecular Characterization of Alternative Splicing Events Misregulated in Lung Cancer

(2010) C. M. Misquitta-Ali et al.   MOLECULAR AND CELLULAR BIOLOGY

Benzo[a]pyrene treatment leads to changes in nuclear protein expression and alternative splicing

(2010) Chunlan Yan et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Characterisation of fibronectin-mediated FAK signalling pathways in lung cancer cell migration and invasion

(2009) X N Meng et al.   BRITISH JOURNAL OF CANCER

Antitumor Activity and Pharmacology of a Selective Focal Adhesion Kinase Inhibitor, PF-562,271

(2008) W. G. Roberts et al.   CANCER RESEARCH

Lung Cancer

(2008) Roy S. Herbst et al.   NEW ENGLAND JOURNAL OF MEDICINE