Extensive temporal transcriptome and microRNA analyses identify molecular mechanisms underlying mitochondrial dysfunction induced by multi-walled carbon nanotubes in human lung cells

MWCNTs of different physicochemical properties cause similar inflammatory responses, but differences in transcriptional and histological markers of fibrosis in mouse lungs

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Endoplasmic Reticulum Stress Induced by Zinc Oxide Nanoparticles Is an Earlier Biomarker for Nanotoxicological Evaluation

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Carcinogenicity of fluoro-edenite, silicon carbide fibres and whiskers, and carbon nanotubes

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A secretomics analysis reveals major differences in the macrophage responses towards different types of carbon nanotubes

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Free radical scavenging and formation by multi-walled carbon nanotubes in cell free conditions and in human bronchial epithelial cells

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Integrative cross-omics analysis in primary mouse hepatocytes unravels mechanisms of cyclosporin A-induced hepatotoxicity

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(2013) Shinya Toyokuni   ADVANCED DRUG DELIVERY REVIEWS

Molecular Basis of Asbestos-Induced Lung Disease

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The role of microRNAs in mitochondria in cancer

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Neoplastic-like transformation effect of single-walled and multi-walled carbon nanotubes compared to asbestos on human lung small airway epithelial cells

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DTW4Omics: Comparing Patterns in Biological Time Series

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Transcriptomic Analysis Reveals Novel Mechanistic Insight into Murine Biological Responses to Multi-Walled Carbon Nanotubes in Lungs and Cultured Lung Epithelial Cells

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Time series analysis of oxidative stress response patterns in HepG2: A toxicogenomics approach

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System-based identification of toxicity pathways associated with multi-walled carbon nanotube-induced pathological responses

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Metabolic characterization of cell systems used in in vitro toxicology testing: Lung cell system BEAS-2B as a working example

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Dose-dependent mesothelioma induction by intraperitoneal administration of multi-wall carbon nanotubes in p53 heterozygous mice

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Mitochondria-Derived Reactive Intermediate Species Mediate Asbestos-Induced Genotoxicity and Oxidative Stress–Responsive Signaling Pathways

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Contribution of MicroRNA-1275 to Claudin11 Protein Suppression via a Polycomb-mediated Silencing Mechanism in Human Glioma Stem-like Cells

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Factoring-in agglomeration of carbon nanotubes and nanofibers for better prediction of their toxicity versus asbestos

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Genotoxicity of short single-wall and multi-wall carbon nanotubes in human bronchial epithelial and mesothelial cells in vitro

(2012) Hanna K. Lindberg et al.   TOXICOLOGY

Multi-walled carbon nanotubes induce apoptosis via mitochondrial pathway and scavenger receptor

(2012) Xiang Wang et al.   TOXICOLOGY IN VITRO

Long, Needle-like Carbon Nanotubes and Asbestos Activate the NLRP3 Inflammasome through a Similar Mechanism

(2011) Jaana Palomäki et al.   ACS Nano

Length-Dependent Retention of Carbon Nanotubes in the Pleural Space of Mice Initiates Sustained Inflammation and Progressive Fibrosis on the Parietal Pleura

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Aging and amyloid beta-induced oxidative DNA damage and mitochondrial dysfunction in Alzheimer's disease: Implications for early intervention and therapeutics

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Significance of uncoupling protein 3 in mitochondrial function upon mid- and long-term dietary high-fat exposure

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Elucidation mechanism of different biological responses to multi-walled carbon nanotubes using four cell lines

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ROS-Mediated p53 Induction of Lpin1 Regulates Fatty Acid Oxidation in Response to Nutritional Stress

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Effects of single and multi walled carbon nanotubes on macrophages: Cyto and genotoxicity and electron microscopy

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Durability and inflammogenic impact of carbon nanotubes compared with asbestos fibres

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Toxicity Testing in the 21st Century: A Vision and a Strategy

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Asbestos, carbon nanotubes and the pleural mesothelium: a review and the hypothesis regarding the role of long fibre retention in the parietal pleura, inflammation and mesothelioma

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Radical Mechanisms in Nitrosamine- and Nitrosamide-Induced Whole-Genome Gene Expression Modulations in Caco-2 Cells

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Using carbon nanotubes to induce micronuclei and double strand breaks of the DNA in human cells

(2009) Jelena Cveticanin et al.   NANOTECHNOLOGY

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Inhaled Multiwalled Carbon Nanotubes Potentiate Airway Fibrosis in Murine Allergic Asthma

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Antimycin A and lipopolysaccharide cause the leakage of superoxide radicals from rat liver mitochondria

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Molecular and genetic changes in asbestos-related lung cancer

(2008) Penny Nymark et al.   CANCER LETTERS

Clastogenic and aneugenic effects of multi-wall carbon nanotubes in epithelial cells

(2008) Julie Muller et al.   CARCINOGENESIS

VEGF stimulation of mitochondrial biogenesis: requirement of AKT3 kinase

(2008) Gary L. Wright et al.   FASEB JOURNAL

Induction of mesothelioma in p53+/− mouse by intraperitoneal application of multi-wall carbon nanotube

(2008) Atsuya Takagi et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study

(2008) Craig A. Poland et al.   Nature Nanotechnology