Beta-hydroxy-beta-methylbutyrate supplementation and skeletal muscle in healthy and muscle-wasting conditions

Determination of β-hydroxy-β-methylbutyrate concentration and enrichment in human plasma using chemical ionization gas chromatography tandem mass spectrometry

(2017) Dillon K. Walker et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Oral supplement enriched in HMB combined with pulmonary rehabilitation improves body composition and health related quality of life in patients with bronchiectasis (Prospective, Randomised Study)

(2016) Gabriel Olveira et al.   CLINICAL NUTRITION

Readmission and mortality in malnourished, older, hospitalized adults treated with a specialized oral nutritional supplement: A randomized clinical trial

(2016) Nicolaas E. Deutz et al.   CLINICAL NUTRITION

Age associated decline in the conversion of leucine to β-Hydroxy-β-Methylbutyrate in rats

(2016) Sathyavageeswaran Shreeram et al.   EXPERIMENTAL GERONTOLOGY

Interaction of Beta-Hydroxy-Beta-Methylbutyrate Free Acid and Adenosine Triphosphate on Muscle Mass, Strength, and Power in Resistance Trained Individuals

(2016) Ryan P. Lowery et al.   JOURNAL OF STRENGTH AND CONDITIONING RESEARCH

The Effect of β-Hydroxy-β-Methylbutyrate on Aerobic Capacity and Body Composition in Trained Athletes

(2016) Krzysztof Durkalec-Michalski et al.   JOURNAL OF STRENGTH AND CONDITIONING RESEARCH

Effects of 4 Weeks of High-Intensity Interval Training and β-Hydroxy-β-Methylbutyric Free Acid Supplementation on the Onset of Neuromuscular Fatigue

(2016) Amelia A. Miramonti et al.   JOURNAL OF STRENGTH AND CONDITIONING RESEARCH

Beta-hydroxy-beta-methylbutyrate ameliorates aging effects in the dendritic tree of pyramidal neurons in the medial prefrontal cortex of both male and female rats

(2016) Daniel G. Kougias et al.   NEUROBIOLOGY OF AGING

Alterations in protein and amino acid metabolism in rats fed a branched-chain amino acid- or leucine-enriched diet during postprandial and postabsorptive states

(2016) Milan Holecek et al.   Nutrition & Metabolism

Effect of Calcium β-Hydroxy-β-Methylbutyrate (CaHMB), Vitamin D, and Protein Supplementation on Postoperative Immobilization in Malnourished Older Adult Patients With Hip Fracture

(2016) Osman Ekinci et al.   NUTRITION IN CLINICAL PRACTICE

Nutrition in cachexia: from bench to bedside

(2016) Masaaki Konishi et al.   Journal of Cachexia Sarcopenia and Muscle

Cellular and Physiological Effects of Dietary Supplementation with β-Hydroxy-β-Methylbutyrate (HMB) and β-Alanine in Late Middle-Aged Mice

(2016) Julian Vallejo et al.   PLoS One

β-Hydroxy-β-methylbutyrate, mitochondrial biogenesis, and skeletal muscle health

(2015) Xi He et al.   AMINO ACIDS

Dietary HMB and β-alanine co-supplementation does not improve in situ muscle function in sedentary, aged male rats

(2015) David W. Russ et al.   Applied Physiology Nutrition and Metabolism

Effect of beta-hydroxy-beta-methylbutyrate supplementation on muscle loss in older adults: A systematic review and meta-analysis

(2015) Hongmei Wu et al.   ARCHIVES OF GERONTOLOGY AND GERIATRICS

The efficacy of a β-hydroxy-β-methylbutyrate supplementation on physical capacity, body composition and biochemical markers in elite rowers: a randomised, double-blind, placebo-controlled crossover study

(2015) Krzysztof Durkalec-Michalski et al.   Journal of the International Society of Sports Nutrition

Ethical guidelines for publishing in the Journal of Cachexia, Sarcopenia and Muscle: update 2015

(2015) Stephan von Haehling et al.   Journal of Cachexia Sarcopenia and Muscle

Conversion of leucine to β-hydroxy-β-methylbutyrate by α-keto isocaproate dioxygenase is required for a potent stimulation of protein synthesis in L6 rat myotubes

(2015) María D. Girón et al.   Journal of Cachexia Sarcopenia and Muscle

Evidence for partial pharmaceutical reversal of the cancer anorexia-cachexia syndrome: the case of anamorelin

(2015) Stefan D. Anker et al.   Journal of Cachexia Sarcopenia and Muscle

β-Hydroxy-β-Methylbutyrate (HMB) Normalizes Dexamethasone-Induced Autophagy-Lysosomal Pathway in Skeletal Muscle

(2015) María D. Girón et al.   PLoS One

Effect of Oral Beta-Hydroxy-Beta-Methylbutyrate (HMB) Supplementation on Physical Performance in Healthy Old Women Over 65 Years: An Open Label Randomized Controlled Trial

(2015) Linda Berton et al.   PLoS One

Beta hydroxy beta methylbutyrate supplementation impairs peripheral insulin sensitivity in healthy sedentary Wistar rats

(2014) C. Y. Yonamine et al.   Acta Physiologica

Glutamine deficiency in extracellular fluid exerts adverse effects on protein and amino acid metabolism in skeletal muscle of healthy, laparotomized, and septic rats

(2014) Milan Holecek et al.   AMINO ACIDS

Effects of β-hydroxy-β-methylbutyrate free acid and cold water immersion on post-exercise markers of muscle damage

(2014) Adam M. Gonzalez et al.   AMINO ACIDS

The effects of 12 weeks of beta-hydroxy-beta-methylbutyrate free acid supplementation on muscle mass, strength, and power in resistance-trained individuals: a randomized, double-blind, placebo-controlled study

(2014) Jacob M. Wilson et al.   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

Assessment of skeletal muscle proteolysis and the regulatory response to nutrition and exercise

(2014) Stefan M. Pasiakos et al.   IUBMB LIFE

The Relative Bioavailability of the Calcium Salt of β-Hydroxy-β-Methylbutyrate Is Greater Than That of the Free Fatty Acid Form in Rats

(2014) Sathyavageeswaran Shreeram et al.   JOURNAL OF NUTRITION

L-leucine, beta-hydroxy-beta-methylbutyric acid (HMB) and creatine monohydrate prevent myostatin-induced Akirin-1/Mighty mRNA down-regulation and myotube atrophy

(2014) Christopher Mobley et al.   Journal of the International Society of Sports Nutrition

High-intensity interval training and β-hydroxy-β-methylbutyric free acid improves aerobic power and metabolic thresholds

(2014) Edward H Robinson et al.   Journal of the International Society of Sports Nutrition

β-Hydroxy-β-methylbutyrate facilitates PI3K/Akt-dependent mammalian target of rapamycin and FoxO1/3a phosphorylations and alleviates tumor necrosis factor α/interferon γ–induced MuRF-1 expression in C2C12 cells

(2014) Kaoru Kimura et al.   NUTRITION RESEARCH

β–Hydroxy β–Methylbutyrate Improves Dexamethasone-Induced Muscle Atrophy by Modulating the Muscle Degradation Pathway in SD Rat

(2014) Kyung Kyun Noh et al.   PLoS One

Prevalence, incidence, and clinical impact of sarcopenia: facts, numbers, and epidemiology-update 2014

(2014) John E. Morley et al.   Journal of Cachexia Sarcopenia and Muscle

β-Hydroxy-β-methylbutyrate free acid reduces markers of exercise-induced muscle damage and improves recovery in resistance-trained men

(2013) Jacob M. Wilson et al.   BRITISH JOURNAL OF NUTRITION

Effect of β-hydroxy-β-methylbutyrate (HMB) on lean body mass during 10 days of bed rest in older adults

(2013) Nicolaas E.P. Deutz et al.   CLINICAL NUTRITION

Effect of calcium β-hydroxy-β-methylbutyrate (CaHMB) with and without resistance training in men and women 65+yrs: A randomized, double-blind pilot trial

(2013) Jeffrey R. Stout et al.   EXPERIMENTAL GERONTOLOGY

β-Hydroxy-β-methylbutyrate (HMB) enhances the proliferation of satellite cells in fast muscles of aged rats during recovery from disuse atrophy

(2013) Stephen E. Alway et al.   EXPERIMENTAL GERONTOLOGY

Protein breakdown in muscle wasting: Role of autophagy-lysosome and ubiquitin-proteasome

(2013) Marco Sandri   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Effects of leucine and its metabolite β-hydroxy-β-methylbutyrate on human skeletal muscle protein metabolism

(2013) D. J. Wilkinson et al.   JOURNAL OF PHYSIOLOGY-LONDON

International Society of Sports Nutrition Position Stand: beta-hydroxy-beta-methylbutyrate (HMB)

(2013) Jacob M Wilson et al.   Journal of the International Society of Sports Nutrition

HMB attenuates muscle loss during sustained energy deficit induced by calorie restriction and endurance exercise

(2013) Bong-Sup Park et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Comparison of the anticatabolic effects of leucine and Ca-β-hydroxy-β-methylbutyrate in experimental models of cancer cachexia

(2013) Kamran A. Mirza et al.   NUTRITION

Leucine and HMB Differentially Modulate Proteasome System in Skeletal Muscle under Different Sarcopenic Conditions

(2013) Igor L. Baptista et al.   PLoS One

Why cachexia kills: examining the causality of poor outcomes in wasting conditions

(2013) Kamyar Kalantar-Zadeh et al.   Journal of Cachexia Sarcopenia and Muscle

β-Hydroxy-β-methylbutyrate (HMB) prevents dexamethasone-induced myotube atrophy

(2012) Zaira Aversa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Protein turnover, amino acid requirements and recommendations for athletes and active populations

(2012) J.R. Poortmans et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Consilience in sarcopenia of cirrhosis

(2012) Srinivasan Dasarathy   Journal of Cachexia Sarcopenia and Muscle

β-Hydroxy-β-methylbutyrate reduces myonuclear apoptosis during recovery from hind limb suspension-induced muscle fiber atrophy in aged rats

(2011) Yanlei Hao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

The effect of HMB supplementation on body composition, fitness, hormonal and inflammatory mediators in elite adolescent volleyball players: a prospective randomized, double-blind, placebo-controlled study

(2011) Shawn Portal et al.   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

Chronic supplementation of beta-hydroxy-beta methylbutyrate (HMβ) increases the activity of the GH/IGF-I axis and induces hyperinsulinemia in rats

(2011) F. Gerlinger-Romero et al.   GROWTH HORMONE & IGF RESEARCH

Vitamin D Status Affects Strength Gains in Older Adults Supplemented With a Combination of β-Hydroxy-β-Methylbutyrate, Arginine, and Lysine

(2011) John C. Fuller et al.   JOURNAL OF PARENTERAL AND ENTERAL NUTRITION

Skeletal muscle loss: cachexia, sarcopenia, and inactivity

(2010) William J Evans   AMERICAN JOURNAL OF CLINICAL NUTRITION

Acute hyperammonemia activates branched-chain amino acid catabolism and decreases their extracellular concentrations: different sensitivity of red and white muscle

(2010) Milan Holecek et al.   AMINO ACIDS

Free acid gel form of β-hydroxy-β-methylbutyrate (HMB) improves HMB clearance from plasma in human subjects compared with the calcium HMB salt

(2010) John C. Fuller et al.   BRITISH JOURNAL OF NUTRITION

Effects of β-hydroxy-β-methylbutyrate treatment in different types of skeletal muscle of intact and septic rats

(2010) Miroslav Kovarik et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Effects of β-Hydroxy-β-Methylbutyrate Supplementation During Resistance Training on Strength, Body Composition, and Muscle Damage in Trained and Untrained Young Men: A Meta-Analysis

(2010) David S Rowlands et al.   JOURNAL OF STRENGTH AND CONDITIONING RESEARCH

Effects of Nine Weeks of β-Hydroxy-β- Methylbutyrate Supplementation on Strength and Body Composition in Resistance Trained Men

(2010) Jasmine S Thomson et al.   JOURNAL OF STRENGTH AND CONDITIONING RESEARCH

Exercise-Induced Muscle Damage Is Not Attenuated by β-Hydroxy-β-Methylbutyrate and α-Ketoisocaproic Acid Supplementation

(2010) David Nunan et al.   JOURNAL OF STRENGTH AND CONDITIONING RESEARCH

Nutritional effect of oral supplement enriched in beta-hydroxy-beta-methylbutyrate, glutamine and arginine on resting metabolic rate after laparoscopic gastric bypass

(2010) Ronald H. Clements et al.   SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES

Year-long Changes in Protein Metabolism in Elderly Men and Women Supplemented With a Nutrition Cocktail of β-Hydroxy-β-methylbutyrate (HMB), L-Arginine, and L-Lysine

(2009) Shawn Baier et al.   JOURNAL OF PARENTERAL AND ENTERAL NUTRITION

Effects of Amino Acids Supplement on Physiological Adaptations to Resistance Training

(2009) WILLIAM J. KRAEMER et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Mechanism of attenuation by β-hydroxy-β-methylbutyrate of muscle protein degradation induced by lipopolysaccharide

(2009) Steven T. Russell et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Attenuation of depression of muscle protein synthesis induced by lipopolysaccharide, tumor necrosis factor, and angiotensin II by β-hydroxy-β-methylbutyrate

(2008) Helen L. Eley et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Effect of beta-hydroxy-beta-methylbutyrate (HMB) on protein metabolism in whole body and in selected tissues

(2008) M. Holecek et al.   FOOD AND CHEMICAL TOXICOLOGY

β-Hydroxy-β-methylbutyrate supplementation reduces tumor growth and tumor cell proliferation ex vivo and prevents cachexia in Walker 256 tumor-bearing rats by modifying nuclear factor-κB expression

(2008) Everson Araújo Nunes et al.   NUTRITION RESEARCH

A randomized, double-blind, placebo-controlled trial of a β-hydroxyl β-methyl butyrate, glutamine, and arginine mixture for the treatment of cancer cachexia (RTOG 0122)

(2008) Lawrence Berk et al.   SUPPORTIVE CARE IN CANCER