The efficacy of Epigallocatechin-3-gallate (green tea) in the treatment of Alzheimer’s disease: an overview of pre-clinical studies and translational perspectives in clinical practice

In Silico Analysis of Green Tea Polyphenols as Inhibitors of AChE and BChE Enzymes in Alzheimer’s Disease Treatment

(2016) Babar Ali et al.   CNS & Neurological Disorders-Drug Targets

Epigallocatechin gallate attenuates amyloid β-induced inflammation and neurotoxicity in EOC 13.31 microglia

(2016) James Cheng-Chung Wei et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Polyphenols in dementia: From molecular basis to clinical trials

(2016) Silvia Molino et al.   LIFE SCIENCES

Epigallocatechin Gallate Attenuates β-Amyloid Generation and Oxidative Stress Involvement of PPARγ in N2a/APP695 Cells

(2016) Zhao-Xu Zhang et al.   NEUROCHEMICAL RESEARCH

The effect of Sailuotong (SLT) on neurocognitive and cardiovascular function in healthy adults: a randomised, double-blind, placebo controlled crossover pilot trial

(2015) Genevieve Z. Steiner et al.   BMC Complementary and Alternative Medicine

(−)-Epigallocatechin-3-gallate attenuates cognitive deterioration in Alzheimer׳s disease model mice by upregulating neprilysin expression

(2015) Xiang Chang et al.   EXPERIMENTAL CELL RESEARCH

Resveratrol decreases the insoluble Aβ1–42 level in hippocampus and protects the integrity of the blood–brain barrier in AD rats

(2015) H.F. Zhao et al.   NEUROSCIENCE

Epigallocatechin-3-gallate enhances clearance of phosphorylated tau in primary neurons

(2015) Adrianne S. Chesser et al.   NUTRITIONAL NEUROSCIENCE

Pinocembrin attenuates hippocampal inflammation, oxidative perturbations and apoptosis in a rat model of global cerebral ischemia reperfusion

(2015) Muhammed A. Saad et al.   Pharmacological Reports

From inflammaging to healthy aging by dietary lifestyle choices: is epigenetics the key to personalized nutrition?

(2015) Katarzyna Szarc vel Szic et al.   Clinical Epigenetics

Inhibitory effect of (−)-epigallocatechin-3-gallate and bleomycin on human pancreatic cancer MiaPaca-2 cell growth

(2015) Sabrina Bimonte et al.   Infectious Agents and Cancer

Investigation of the effects of solid lipid curcumin on cognition and mood in a healthy older population

(2014) Katherine HM Cox et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Acute effects of tea constituents L-theanine, caffeine, and epigallocatechin gallate on cognitive function and mood: a systematic review and meta-analysis

(2014) David A Camfield et al.   NUTRITION REVIEWS

Green Tea Consumption Affects Cognitive Dysfunction in the Elderly: A Pilot Study

(2014) Kazuki Ide et al.   Nutrients

Acute effects of tea consumption on attention and mood

(2013) Suzanne J Einöther et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Possible Therapeutic Uses of Salvia triloba and Piper nigrum in Alzheimer's Disease–Induced Rats

(2013) Hanaa H. Ahmed et al.   JOURNAL OF MEDICINAL FOOD

(−)-Epigallocatechin-3-gallate alleviates spatial memory impairment in APP/PS1 mice by restoring IRS-1 signaling defects in the hippocampus

(2013) Ning Jia et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Epigallocatechin-3-gallate: a useful, effective and safe clinical approach for targeted prevention and individualised treatment of neurological diseases?

(2013) Anja Mähler et al.   EPMA Journal

Green tea (−)epigallocatechin-3-gallate reverses oxidative stress and reduces acetylcholinesterase activity in a streptozotocin-induced model of dementia

(2012) Regina Biasibetti et al.   BEHAVIOURAL BRAIN RESEARCH

Brain Insulin Resistance and Deficiency as Therapeutic Targets in Alzheimers Disease

(2012) Suzanne M. de la Monte   Current Alzheimer Research

Neuroinflammation, Oxidative Stress and the Pathogenesis of Alzheimers Disease

(2012) Paula Agostinho et al.   CURRENT PHARMACEUTICAL DESIGN

Epigallocatechin gallate, cerebral blood flow parameters, cognitive performance and mood in healthy humans: a double-blind, placebo-controlled, crossover investigation

(2012) Emma L. Wightman et al.   HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL

Pharmacokinetics and Blood–Brain Barrier Penetration of (+)-Catechin and (−)-Epicatechin in Rats by Microdialysis Sampling Coupled to High-Performance Liquid Chromatography with Chemiluminescence Detection

(2012) Liang Wu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Epigallocatechin-3-gallate prevents systemic inflammation-induced memory deficiency and amyloidogenesis via its anti-neuroinflammatory properties

(2012) Young-Jung Lee et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Acute neurocognitive effects of epigallocatechin gallate (EGCG)

(2011) Andrew Scholey et al.   APPETITE

The overlap between neurodegenerative and vascular factors in the pathogenesis of dementia

(2010) Costantino Iadecola   ACTA NEUROPATHOLOGICA

Nanolipidic particles improve the bioavailability and α-secretase inducing ability of epigallocatechin-3-gallate (EGCG) for the treatment of Alzheimer's disease

(2010) Adam Smith et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

EGCG protects against oxidized LDL-induced endothelial dysfunction by inhibiting LOX-1-mediated signaling

(2010) Hsiu-Chung Ou et al.   JOURNAL OF APPLIED PHYSIOLOGY

Fish oil enhances anti-amyloidogenic properties of green tea EGCG in Tg2576 mice

(2010) Brian Giunta et al.   NEUROSCIENCE LETTERS

EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity

(2010) Jan Bieschke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CNS Inflammation and Macrophage/Microglial Biology Associated with HIV-1 Infection

(2009) Anjana Yadav et al.   Journal of Neuroimmune Pharmacology

Green tea epigallocatechin-3-gallate (EGCG) reduces β-amyloid mediated cognitive impairment and modulates tau pathology in Alzheimer transgenic mice

(2008) Kavon Rezai-Zadeh et al.   BRAIN RESEARCH

Anti-angiogenic effects of green tea catechin on an experimental endometriosis mouse model

(2008) H. Xu et al.   HUMAN REPRODUCTION

Challenges for Research on Polyphenols from Foods in Alzheimer’s Disease: Bioavailability, Metabolism, and Cellular and Molecular Mechanisms

(2008) Manjeet Singh et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Caffeine blocks disruption of blood brain barrier in a rabbit model of Alzheimer's disease

(2008) Xuesong Chen et al.   Journal of Neuroinflammation

Epigallocatechin-3-O-gallate inhibits TNFα-induced monocyte chemotactic protein-1 production from vascular endothelial cells

(2008) Hee Yul Ahn et al.   LIFE SCIENCES

EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers

(2008) Dagmar E Ehrnhoefer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Epigallocatechin gallate (EGCG) suppresses β-amyloid-induced neurotoxicity through inhibiting c-Abl/FE65 nuclear translocation and GSK3β activation

(2007) Chih-Li Lin et al.   NEUROBIOLOGY OF AGING