New Insight into Inter-kingdom Communication: Horizontal Transfer of Mobile Small RNAs

The atypical genesis and bioavailability of the plant-based small RNA MIR2911: Bulking up while breaking down

(2017) Jian Yang et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Deficiency of microRNAmiR-34aexpands cell fate potential in pluripotent stem cells

(2017) Yong Jin Choi et al.   SCIENCE

Detection of dietetically absorbed maize-derived microRNAs in pigs

(2017) Yi Luo et al.   Scientific Reports

Role of plant MicroRNA in cross-species regulatory networks of humans

(2016) Hao Zhang et al.   BMC Systems Biology

The Host Shapes the Gut Microbiota via Fecal MicroRNA

(2016) Shirong Liu et al.   Cell Host & Microbe

Cross-kingdom inhibition of breast cancer growth by plant miR159

(2016) Andrew R Chin et al.   CELL RESEARCH

Genome-wide identification and functional annotation of miRNAs in anti-inflammatory plant and their cross-kingdom regulation in Homo sapiens

(2016) Ankita Sharma et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Bioinformatics Prediction and Experimental Validation of MicroRNAs Involved in Cross-Kingdom Interaction

(2016) Stefano Pirrò et al.   JOURNAL OF COMPUTATIONAL BIOLOGY

Distinct Functions of Argonaute Slicer in siRNA Maturation and Heterochromatin Formation

(2016) Ruchi Jain et al.   MOLECULAR CELL

Targeting insect mitochondrial complex I for plant protection

(2016) Xiu-Ming Wu et al.   PLANT BIOTECHNOLOGY JOURNAL

miR156a Mimic Represses the Epithelial–Mesenchymal Transition of Human Nasopharyngeal Cancer Cells by Targeting Junctional Adhesion Molecule A

(2016) Yunhong Tian et al.   PLoS One

Anomalous uptake and circulatory characteristics of the plant-based small RNA MIR2911

(2016) Jian Yang et al.   Scientific Reports

Identification of Dietetically Absorbed Rapeseed (Brassica campestrisL.) Bee Pollen MicroRNAs in Serum of Mice

(2016) Xuan Chen et al.   Biomed Research International

Plant microRNAs as novel immunomodulatory agents

(2016) Duccio Cavalieri et al.   Scientific Reports

Circulating plant miRNAs can regulate human gene expression in vitro

(2016) Chiara Pastrello et al.   Scientific Reports

Gene regulation by dietary microRNAs

(2015) Janos Zempleni et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Horizontal transfer of exosomal microRNAs transduce apoptotic signals between pancreatic beta-cells

(2015) Claudiane Guay et al.   Cell Communication and Signaling

A novel chemopreventive strategy based on therapeutic microRNAs produced in plants

(2015) Sizolwenkosi Mlotshwa et al.   CELL RESEARCH

Detection of dietary plant-based small RNAs in animals

(2015) Jian Yang et al.   CELL RESEARCH

Conversations between kingdoms: small RNAs

(2015) Arne Weiberg et al.   CURRENT OPINION IN BIOTECHNOLOGY

Uptake and Function Studies of Maternal Milk-derived MicroRNAs

(2015) Alexandra C. Title et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effective detection and quantification of dietetically absorbed plant microRNAs in human plasma

(2015) Hongwei Liang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Determination of the potential bioavailability of plant microRNAs using a simulated human digestion process

(2015) Anna Philip et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth

(2015) Lin Zhang et al.   NATURE

Sperm tsRNAs contribute to intergenerational inheritance of an acquired metabolic disorder

(2015) Q. Chen et al.   SCIENCE

Biogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals

(2015) U. Sharma et al.   SCIENCE

Dietary RNAs: New Stories Regarding Oral Delivery

(2015) Jian Yang et al.   Nutrients

Targeted exosome-mediated delivery of opioid receptor Mu siRNA for the treatment of morphine relapse

(2015) Yuchen Liu et al.   Scientific Reports

Nonfunctional ingestion of plant miRNAs in silkworm revealed by digital droplet PCR and transcriptome analysis

(2015) Ling Jia et al.   Scientific Reports

Detection of an Abundant Plant-Based Small RNA in Healthy Consumers

(2015) Jian Yang et al.   PLoS One

Computational Characterization of Exogenous MicroRNAs that Can Be Transferred into Human Circulation

(2015) Jiang Shu et al.   PLoS One

Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles

(2014) Marina Colombo et al.   Annual Review of Cell and Developmental Biology

Small RNAs: A New Paradigm in Plant-Microbe Interactions

(2014) Arne Weiberg et al.   Annual Review of Phytopathology

Microvesicle-mediated delivery of transforming growth factor β1 siRNA for the suppression of tumor growth in mice

(2014) Yaqin Zhang et al.   BIOMATERIALS

Meta-analysis of tRNA derived RNA fragments reveals that they are evolutionarily conserved and associate with AGO proteins to recognize specific RNA targets

(2014) Pankaj Kumar et al.   BMC BIOLOGY

Small RNAs from plants, bacteria and fungi within the order Hypocreales are ubiquitous in human plasma

(2014) Meabh Beatty et al.   BMC GENOMICS

Cancer-Secreted miR-105 Destroys Vascular Endothelial Barriers to Promote Metastasis

(2014) Weiying Zhou et al.   CANCER CELL

Honeysuckle-encoded atypical microRNA2911 directly targets influenza A viruses

(2014) Zhen Zhou et al.   CELL RESEARCH

Tumor-secreted miR-214 induces regulatory T cells: a major link between immune evasion and tumor growth

(2014) Yuan Yin et al.   CELL RESEARCH

MicroRNAs Are Absorbed in Biologically Meaningful Amounts from Nutritionally Relevant Doses of Cow Milk and Affect Gene Expression in Peripheral Blood Mononuclear Cells, HEK-293 Kidney Cell Cultures, and Mouse Livers

(2014) Scott R. Baier et al.   JOURNAL OF NUTRITION

Interspecies communication between plant and mouse gut host cells through edible plant derived exosome-like nanoparticles

(2014) Jingyao Mu et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Small RNAs break out: the molecular cell biology of mobile small RNAs

(2014) Peter Sarkies et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Host-induced post-transcriptional hairpin RNA-mediated gene silencing of vital fungal genes confers efficient resistance against Fusarium wilt in banana

(2014) Siddhesh B. Ghag et al.   PLANT BIOTECHNOLOGY JOURNAL

Mining of public sequencing databases supports a non-dietary origin for putative foreign miRNAs: underestimated effects of contamination in NGS

(2014) J. P. Tosar et al.   RNA

Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity

(2014) Amy H. Buck et al.   Nature Communications

Trans-kingdom Cross-Talk: Small RNAs on the Move

(2014) Marijn Knip et al.   PLoS Genetics

Parasite-Derived MicroRNAs in Host Serum As Novel Biomarkers of Helminth Infection

(2014) Anna M. Hoy et al.   PLoS Neglected Tropical Diseases

Assessing the survival of exogenous plant microRNA in mice

(2014) GaoFeng Liang et al.   Food Science & Nutrition

Reply to Lack of detectable oral bioavailability of plant microRNAs after feeding in mice

(2013) Xi Chen et al.   NATURE BIOTECHNOLOGY

Lack of detectable oral bioavailability of plant microRNAs after feeding in mice

(2013) Brent Dickinson et al.   NATURE BIOTECHNOLOGY

Deep sequencing-based identification of pathogen-specific microRNAs in the plasma of rabbits infected with Schistosoma japonicum

(2013) GUOFENG CHENG et al.   PARASITOLOGY

Host-induced gene silencing of cytochrome P450 lanosterol C14 -demethylase-encoding genes confers strong resistance to Fusarium species

(2013) A. Koch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Real-time quantitative PCR and droplet digital PCR for plant miRNAs in mammalian blood provide little evidence for general uptake of dietary miRNAs

(2013) Kenneth W. Witwer et al.   RNA Biology

Ineffective delivery of diet-derived microRNAs to recipient animal organisms

(2013) Jonathan W. Snow et al.   RNA Biology

Fungal Small RNAs Suppress Plant Immunity by Hijacking Host RNA Interference Pathways

(2013) Arne Weiberg et al.   SCIENCE

Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs

(2013) Carolina Villarroya-Beltri et al.   Nature Communications

Analysis of plant-derived miRNAs in animal small RNA datasets

(2012) Yuanji Zhang et al.   BMC GENOMICS

Translocation of Sickle Cell Erythrocyte MicroRNAs into Plasmodium falciparum Inhibits Parasite Translation and Contributes to Malaria Resistance

(2012) Gregory LaMonte et al.   Cell Host & Microbe

Intercellular communication: diverse structures for exchange of genetic information

(2012) Maria Mittelbrunn et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Secreted microRNAs: a new form of intercellular communication

(2012) Xi Chen et al.   TRENDS IN CELL BIOLOGY

Escherichia coli noncoding RNAs can affect gene expression and physiology of Caenorhabditis elegans

(2012) Huijie Liu et al.   Nature Communications

Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes

(2011) A. Montecalvo et al.   BLOOD

Exogenous plant MIR168a specifically targets mammalian LDLRAP1: evidence of cross-kingdom regulation by microRNA

(2011) Lin Zhang et al.   CELL RESEARCH

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

(2011) Lydia Alvarez-Erviti et al.   NATURE BIOTECHNOLOGY

A Versatile Monosaccharide Transporter That Operates in the Arbuscular Mycorrhizal Fungus Glomus sp Is Crucial for the Symbiotic Relationship with Plants

(2011) N. Helber et al.   PLANT CELL

Dicer-Independent Primal RNAs Trigger RNAi and Heterochromatin Formation

(2010) Mario Halic et al.   CELL

Secreted Monocytic miR-150 Enhances Targeted Endothelial Cell Migration

(2010) Yujing Zhang et al.   MOLECULAR CELL

HIGS: Host-Induced Gene Silencing in the Obligate Biotrophic Fungal PathogenBlumeria graminis

(2010) Daniela Nowara et al.   PLANT CELL

Optimization of enzymatic reaction conditions for generating representative pools of cDNA from small RNA

(2010) D. B. Munafo et al.   RNA

Origins and Mechanisms of miRNAs and siRNAs

(2009) Richard W. Carthew et al.   CELL

RNA translocation between parasitic plants and their hosts

(2009) James H Westwood et al.   PEST MANAGEMENT SCIENCE

Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases

(2008) Xi Chen et al.   CELL RESEARCH

Environmental RNA interference

(2008) Jennifer S. Whangbo et al.   TRENDS IN GENETICS