The Importance of the Expendable: Toxin–Antitoxin Genes in Plasmids and Chromosomes

Contribution of the Chromosomal ccdAB Operon to Bacterial Drug Tolerance

(2017) Kritika Gupta et al.   JOURNAL OF BACTERIOLOGY

The effector AvrRxo1 phosphorylates NAD in planta

(2017) Teja Shidore et al.   PLoS Pathogens

Commentary: What Is the Link between Stringent Response, Endoribonuclease Encoding Type II Toxin-Antitoxin Systems and Persistence?

(2017) Laurence Van Melderen et al.   Frontiers in Microbiology

Molecular mechanisms and clinical implications of bacterial persistence

(2016) Joran Elie Michiels et al.   DRUG RESISTANCE UPDATES

3′-NADP and 3′-NAADP, Two Metabolites Formed by the Bacterial Type III Effector AvrRxo1

(2016) Felix Schuebel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Emerging Roles of Toxin-Antitoxin Modules in Bacterial Pathogenesis

(2016) Barbara Kędzierska et al.   MOLECULES

Toxin-antitoxin systems in bacterial growth arrest and persistence

(2016) Rebecca Page et al.   Nature Chemical Biology

tRNA-mediated codon-biased translation in mycobacterial hypoxic persistence

(2016) Yok Hian Chionh et al.   Nature Communications

Heterologous expression of the Streptococcus pneumoniae yoeB and pezT toxin genes is lethal in Chlorella vulgaris

(2016) Shet Lee Ng et al.   Algal Research-Biomass Biofuels and Bioproducts

The Streptococcus pneumoniae pezAT Toxin–Antitoxin System Reduces β-Lactam Resistance and Genetic Competence

(2016) Wai T. Chan et al.   Frontiers in Microbiology

What Is the Link between Stringent Response, Endoribonuclease Encoding Type II Toxin–Antitoxin Systems and Persistence?

(2016) Bhaskar C. M. Ramisetty et al.   Frontiers in Microbiology

AvrRxo1 Is a Bifunctional Type III Secreted Effector and Toxin-Antitoxin System Component with Homologs in Diverse Environmental Contexts

(2016) Lindsay R. Triplett et al.   PLoS One

A toxin antitoxin system promotes the maintenance of the IncA/C-mobilizable Salmonella Genomic Island 1

(2016) Kevin T. Huguet et al.   Scientific Reports

Comprehensive Functional Analysis of the 18 Vibrio cholerae N16961 Toxin-Antitoxin Systems Substantiates Their Role in Stabilizing the Superintegron

(2015) Naeem Iqbal et al.   JOURNAL OF BACTERIOLOGY

The chromosomal SezAT toxin-antitoxin system promotes the maintenance of the SsPI-1 pathogenicity island in epidemicStreptococcus suis

(2015) Xinyue Yao et al.   MOLECULAR MICROBIOLOGY

Crystal Structure of Xanthomonas AvrRxo1-ORF1, a Type III Effector with a Polynucleotide Kinase Domain, and Its Interactor AvrRxo1-ORF2

(2015) Qian Han et al.   STRUCTURE

Distinct type I and type II toxin-antitoxin modules control Salmonella lifestyle inside eukaryotic cells

(2015) Damián Lobato-Márquez et al.   Scientific Reports

Coupling between the Basic Replicon and the Kis-Kid Maintenance System of Plasmid R1: Modulation by Kis Antitoxin Levels and Involvement in Control of Plasmid Replication

(2015) Juan López-Villarejo et al.   Toxins

tRNAs taking charge

(2015) Jonathan W. Cruz et al.   Pathogens and Disease

Molecular Mechanisms Underlying Bacterial Persisters

(2014) Etienne Maisonneuve et al.   CELL

Role of Toxin ζ and Starvation Responses in the Sensitivity to Antimicrobials

(2014) Mariangela Tabone et al.   PLoS One

Toxin Kid uncouples DNA replication and cell division to enforce retention of plasmid R1 in Escherichia coli cells

(2014) B. Pimentel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Internalization of Salmonella by Macrophages Induces Formation of Nonreplicating Persisters

(2014) S. Helaine et al.   SCIENCE

Toxin-Antitoxin Systems as Multilevel Interaction Systems

(2014) Nathalie Goeders et al.   Toxins

Functional validation of putative toxin-antitoxin genes from the Gram-positive pathogen Streptococcus pneumoniae: phd-doc is the fourth bona-fide operon

(2014) Wai Ting Chan et al.   Frontiers in Microbiology

Nucleotide Sequence Analysis of Integrative Conjugative Element Tn5253of Streptococcus pneumoniae

(2013) Francesco Iannelli et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

To be or not to be: regulation of restriction–modification systems and other toxin–antitoxin systems

(2013) Iwona Mruk et al.   NUCLEIC ACIDS RESEARCH

Toxin-Antitoxin Genes of the Gram-Positive Pathogen Streptococcus pneumoniae: So Few and Yet So Many

(2012) Wai Ting Chan et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Kis antitoxin couples plasmid R1 replication and parD (kis,kid) maintenance modules

(2012) Juan López-Villarejo et al.   PLASMID

Additional role for the ccd operon of F-plasmid as a transmissible persistence factor

(2012) A. Tripathi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selective translation during stress in Escherichia coli

(2012) Isabella Moll et al.   TRENDS IN BIOCHEMICAL SCIENCES

ε/ζ systems: their role in resistance, virulence, and their potential for antibiotic development

(2011) Hannes Mutschler et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Bacterial persistence by RNA endonucleases

(2011) Etienne Maisonneuve et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Novel Mechanism of Programmed Cell Death in Bacteria by Toxin–Antitoxin Systems Corrupts Peptidoglycan Synthesis

(2011) Hannes Mutschler et al.   PLOS BIOLOGY

The Three Vibrio cholerae Chromosome II-Encoded ParE Toxins Degrade Chromosome I following Loss of Chromosome II

(2010) J. Yuan et al.   JOURNAL OF BACTERIOLOGY

Three new RelE-homologous mRNA interferases ofEscherichia colidifferentially induced by environmental stresses

(2009) Mikkel Christensen-Dalsgaard et al.   MOLECULAR MICROBIOLOGY

A Toxin–Antitoxin System Promotes the Maintenance of an Integrative Conjugative Element

(2009) Rachel A. F. Wozniak et al.   PLoS Genetics