Functional validation of putative toxin-antitoxin genes from the Gram-positive pathogen Streptococcus pneumoniae: phd-doc is the fourth bona-fide operon

Doc Toxin Is a Kinase That Inactivates Elongation Factor Tu

(2014) Jonathan W. Cruz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A widespread bacteriophage abortive infection system functions through a Type IV toxin–antitoxin mechanism

(2014) Ron L. Dy et al.   NUCLEIC ACIDS RESEARCH

23S rRNA as an a-Maz-ing new bacterial toxin target

(2014) Jason M Schifano et al.   RNA Biology

Toxin-Antitoxin Systems as Multilevel Interaction Systems

(2014) Nathalie Goeders et al.   Toxins

Nucleotide Sequence Analysis of Integrative Conjugative Element Tn5253of Streptococcus pneumoniae

(2013) Francesco Iannelli et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Discovery of Functional Toxin/Antitoxin Systems in Bacteria by Shotgun Cloning

(2013) Hila Sberro et al.   MOLECULAR CELL

The Fic protein Doc uses an inverted substrate to phosphorylate and inactivate EF-Tu

(2013) Daniel Castro-Roa et al.   Nature Chemical Biology

Conserved Inhibitory Mechanism and Competent ATP Binding Mode for Adenylyltransferases with Fic Fold

(2013) Arnaud Goepfert et al.   PLoS One

Plasmids as models for studying macromolecular interactions: the pMV158 paradigm

(2013) Manuel Espinosa   RESEARCH IN MICROBIOLOGY

Antitoxin MqsA Represses Curli Formation Through the Master Biofilm Regulator CsgD

(2013) Valerie W. C. Soo et al.   Scientific Reports

A Toxin-Antitoxin Module of Salmonella Promotes Virulence in Mice

(2013) Miguel A. De la Cruz et al.   PLoS Pathogens

Bacterial Persistence and Toxin-Antitoxin Loci

(2012) Kenn Gerdes et al.   Annual Review of Microbiology

Comprehensive comparative-genomic analysis of Type 2 toxin-antitoxin systems and related mobile stress response systems in prokaryotes

(2012) Kira S Makarova et al.   Biology Direct

Toxin-antitoxin loci vapBC-1 and vapXD contribute to survival and virulence in nontypeable Haemophilus influenzae

(2012) Dabin Ren et al.   BMC MICROBIOLOGY

Toxin-Antitoxin Genes of the Gram-Positive Pathogen Streptococcus pneumoniae: So Few and Yet So Many

(2012) Wai Ting Chan et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Adenylylation control by intra- or intermolecular active-site obstruction in Fic proteins

(2012) Philipp Engel et al.   NATURE

The toxin-antitoxin proteins relBE2Spn of Streptococcus pneumoniae: Characterization and association to their DNA target

(2012) Inma Moreno-Córdoba et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Toxin-Antitoxin Systems Are Important for Niche-Specific Colonization and Stress Resistance of Uropathogenic Escherichia coli

(2012) J. Paul Norton et al.   PLoS Pathogens

Genetic Regulation of the yefM-yoeB Toxin-Antitoxin Locus of Streptococcus pneumoniae

(2011) W. T. Chan et al.   JOURNAL OF BACTERIOLOGY

Diversity of bacterial type II toxin–antitoxin systems: a comprehensive search and functional analysis of novel families

(2011) Raphaël Leplae et al.   NUCLEIC ACIDS RESEARCH

ICEberg: a web-based resource for integrative and conjugative elements found in Bacteria

(2011) Dexi Bi et al.   NUCLEIC ACIDS RESEARCH

PHAST: A Fast Phage Search Tool

(2011) Y. Zhou et al.   NUCLEIC ACIDS RESEARCH

Construction of a plasmid vector based on the pMV158 replicon for cloning and inducible gene expression in Streptococcus pneumoniae

(2011) José A. Ruiz-Masó et al.   PLASMID

Adenylylation: renaissance of a forgotten post-translational modification

(2011) Aymelt Itzen et al.   TRENDS IN BIOCHEMICAL SCIENCES

A Novel Mechanism of Programmed Cell Death in Bacteria by Toxin–Antitoxin Systems Corrupts Peptidoglycan Synthesis

(2011) Hannes Mutschler et al.   PLOS BIOLOGY

AMPylation: something old is new again

(2011) Andrew Woolery   Frontiers in Microbiology

Novel plasmid-based genetic tools for the study of promoters and terminators in Streptococcus pneumoniae and Enterococcus faecalis

(2010) Sofía Ruiz-Cruz et al.   JOURNAL OF MICROBIOLOGICAL METHODS

The relBE2Spn Toxin-Antitoxin System of Streptococcus pneumoniae: Role in Antibiotic Tolerance and Functional Conservation in Clinical Isolates

(2010) Concha Nieto et al.   PLoS One

Interdependence of Cell Growth and Gene Expression: Origins and Consequences

(2010) M. Scott et al.   SCIENCE

The Chromosomal Toxin Gene yafQ Is a Determinant of Multidrug Tolerance for Escherichia coli Growing in a Biofilm

(2009) J. J. Harrison et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Environmental stress and evolvability in microbial systems

(2009) F. Baquero   CLINICAL MICROBIOLOGY AND INFECTION

The Inhibitory Mechanism of Protein Synthesis by YoeB, anEscherichia coliToxin

(2009) Yonglong Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fido, a Novel AMPylation Domain Common to Fic, Doc, and AvrB

(2009) Lisa N. Kinch et al.   PLoS One

The phage abortive infection system, ToxIN, functions as a protein–RNA toxin–antitoxin pair

(2009) Peter C. Fineran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comprehensive Functional Analysis of Mycobacterium tuberculosis Toxin-Antitoxin Systems: Implications for Pathogenesis, Stress Responses, and Evolution

(2009) Holly R. Ramage et al.   PLoS Genetics

MazF, an mRNA Interferase, Mediates Programmed Cell Death during Multicellular Myxococcus Development

(2008) Hirofumi Nariya et al.   CELL

HicA of Escherichia coli Defines a Novel Family of Translation-Independent mRNA Interferases in Bacteria and Archaea

(2008) M. G. Jorgensen et al.   JOURNAL OF BACTERIOLOGY

Doc of Prophage P1 Is Inhibited by Its Antitoxin Partner Phd through Fold Complementation

(2008) Abel Garcia-Pino et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bacterial addiction module toxin Doc inhibits translation elongation through its association with the 30S ribosomal subunit

(2008) M. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA