Lipopolysaccharide Upregulated Intestinal Epithelial Cell Expression of Fn14 and Activation of Fn14 Signaling Amplify Intestinal TLR4-Mediated Inflammation

Endogenous TWEAK is critical for regulating the function of mouse uterine natural killer cells in an immunological model of pregnancy loss

(2016) Xuefeng Qi et al.   IMMUNOLOGY

Blocking TWEAK-Fn14 interaction inhibits hematopoietic stem cell transplantation-induced intestinal cell death and reduces GVHD

(2015) M. Chopra et al.   BLOOD

Lipopolysaccharide Regulation of Intestinal Tight Junction Permeability Is Mediated by TLR4 Signal Transduction Pathway Activation of FAK and MyD88

(2015) Shuhong Guo et al.   JOURNAL OF IMMUNOLOGY

Fn14 Receptor Appears as a Modulator Of Ovarian Steroid-Related Regulation Of Goat Endometrial Epithelial Cell IL-18 expression

(2014) Mingzhu Lei et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Regulation of Fibroblast Growth Factor-inducible 14 (Fn14) Expression Levels via Ligand-independent Lysosomal Degradation

(2014) Sujatha Gurunathan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intestinal Expression of Fas and Fas Ligand Is Upregulated by Bacterial Signaling through TLR4 and TLR5, with Activation of Fas Modulating Intestinal TLR-Mediated Inflammation

(2014) Philana Fernandes et al.   JOURNAL OF IMMUNOLOGY

Characteristic and Functional Analysis of a Newly Established Porcine Small Intestinal Epithelial Cell Line

(2014) Jing Wang et al.   PLoS One

TWEAK/Fn14 axis: The current paradigm of tissue injury-inducible function in the midst of complexities

(2014) Linda C. Burkly   SEMINARS IN IMMUNOLOGY

A Comparative Review of Toll-Like Receptor 4 Expression and Functionality in Different Animal Species

(2014) Céline Vaure et al.   Frontiers in Immunology

TWEAK/Fn14 pathway promotes a T helper 2-type chronic colitis with fibrosis in mice

(2013) A Son et al.   Mucosal Immunology

TWEAK-Independent Fn14 Self-Association and NF-κB Activation Is Mediated by the C-Terminal Region of the Fn14 Cytoplasmic Domain

(2013) Sharron A. N. Brown et al.   PLoS One

Toll-like receptor signaling and regulation of intestinal immunity

(2013) Karishma Kamdar et al.   Virulence

Lipopolysaccharide Causes an Increase in Intestinal Tight Junction Permeability in Vitro and in Vivo by Inducing Enterocyte Membrane Expression and Localization of TLR-4 and CD14

(2012) Shuhong Guo et al.   AMERICAN JOURNAL OF PATHOLOGY

Interleukin-13 Damages Intestinal Mucosa via TWEAK and Fn14 in Mice—A Pathway Associated With Ulcerative Colitis

(2011) Rei Kawashima et al.   GASTROENTEROLOGY

TWEAK/Fn14 pathway: an immunological switch for shaping tissue responses

(2011) Linda C. Burkly et al.   IMMUNOLOGICAL REVIEWS

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Effects of dietary glycyl-glutamine on growth performance, small intestinal integrity, and immune responses of weaning piglets challenged with lipopolysaccharide1

(2009) Z. Y. Jiang et al.   JOURNAL OF ANIMAL SCIENCE

Fibroblast growth factor-inducible 14 (Fn14) is expressed in the lower genital tract and may play a role in amplifying inflammation during infection

(2009) Eugene S. Han et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

TWEAK/Fn14 Pathway: A Nonredundant Role in Intestinal Damage in Mice Through a TWEAK/Intestinal Epithelial Cell Axis

(2008) Taeko Dohi et al.   GASTROENTEROLOGY

The TWEAK–Fn14 cytokine–receptor axis: discovery, biology and therapeutic targeting

(2008) Jeffrey A. Winkles   NATURE REVIEWS DRUG DISCOVERY