Mechanisms of Severe Mortality-Associated Bacterial Co-infections Following Influenza Virus Infection

Surges of advanced medical support associated with influenza outbreaks

(2017) J. C. KING et al.   EPIDEMIOLOGY AND INFECTION

Heterologous post-infection immunity against Egyptian avian influenza virus (AIV) H9N2 modulates the course of subsequent infection by highly pathogenic AIV H5N1, but vaccination immunity does not

(2017) Mahmoud M. Naguib et al.   JOURNAL OF GENERAL VIROLOGY

Sequence analysis of haemagglutinin and neuraminidase of H1N1 strain from a patient coinfected with Mycobacterium tuberculosis

(2017) Ahmed N. Alghamdi et al.   MOLECULAR AND CELLULAR PROBES

Influenza: A viral world war

(2017) Tilli Tansey   NATURE

Inflammatory Responses Regulating Alveolar Ion Transport during Pulmonary Infections

(2017) Christin Peteranderl et al.   Frontiers in Immunology

Bacterial coinfection is associated with severity of avian influenza A (H7N9), and procalcitonin is a useful marker for early diagnosis

(2016) Meifang Yang et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

The frequency of influenza and bacterial coinfection: a systematic review and meta-analysis

(2016) Eili Y. Klein et al.   Influenza and Other Respiratory Viruses

Bacterial and viral co-infections complicating severe influenza: Incidence and impact among 507 U.S. patients, 2013–14

(2016) Nirav S. Shah et al.   JOURNAL OF CLINICAL VIROLOGY

Nox2-derived oxidative stress results in inefficacy of antibiotics against post-influenzaS. aureuspneumonia

(2016) Keer Sun et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Quantifying the therapeutic requirements and potential for combination therapy to prevent bacterial coinfection during influenza

(2016) Amber M. Smith   JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS

Influenza virus infection causes neutrophil dysfunction through reduced G-CSF production and an increased risk of secondary bacteria infection in the lung

(2016) Hiroki Ishikawa et al.   VIROLOGY

Oseltamivir PK/PD Modeling and Simulation to Evaluate Treatment Strategies against Influenza-Pneumococcus Coinfection

(2016) Alessandro Boianelli et al.   Frontiers in Cellular and Infection Microbiology

Influenza-induced type I interferon enhances susceptibility to gram-negative and gram-positive bacterial pneumonia in mice

(2015) Benjamin Lee et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Pneumolysin expression by streptococcus pneumoniae protects colonized mice from influenza virus-induced disease

(2014) Amaya I. Wolf et al.   VIROLOGY

Transcriptional adaptation of pneumococci and human pharyngeal cells in the presence of a virus infection

(2013) Sheila Z Kimaro Mlacha et al.   BMC GENOMICS

Pathogenesis ofStaphylococcus aureusnecrotizing pneumonia: the role of PVL and an influenza coinfection

(2013) Bettina Löffler et al.   Expert Review of Anti-Infective Therapy

Depletion of Alveolar Macrophages during Influenza Infection Facilitates Bacterial Superinfections

(2013) H. E. Ghoneim et al.   JOURNAL OF IMMUNOLOGY

Immune Dysfunction and Bacterial Coinfections following Influenza

(2013) D. W. Metzger et al.   JOURNAL OF IMMUNOLOGY

Influence of prior pandemic A(H1N1)2009 virus infection on invasion of MDCK cells by community-associated methicillin-resistant Staphylococcus aureus

(2013) Yoko Takayama et al.   JOURNAL OF INFECTION AND CHEMOTHERAPY

Clinical Findings in 111 Cases of Influenza A (H7N9) Virus Infection

(2013) Hai-Nv Gao et al.   NEW ENGLAND JOURNAL OF MEDICINE

Kinetic Characterization of PB1-F2-Mediated Immunopathology during Highly Pathogenic Avian H5N1 Influenza Virus Infection

(2013) Olivier Leymarie et al.   PLoS One

Genome-wide fitness profiling reveals adaptations required by Haemophilus in coinfection with influenza A virus in the murine lung

(2013) S. M. Wong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of Tissue Protection in Lethal Respiratory Viral-Bacterial Coinfection

(2013) A. M. Jamieson et al.   SCIENCE

Bacterial colonization dampens influenza-mediated acute lung injury via induction of M2 alveolar macrophages

(2013) Jian Wang et al.   Nature Communications

Seasonal H3N2 influenza A virus fails to enhanceStaphylococcus aureusco-infection in a non-human primate respiratory tract infection model

(2013) Scott D Kobayashi et al.   Virulence

Global Gene Expression Profiling in Infants With Acute Respiratory Syncytial Virus Broncholitis Demonstrates Systemic Activation of Interferon Signaling Networks

(2012) Kristine L. Bucasas et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Poly I:C Enhances Susceptibility to Secondary Pulmonary Infections by Gram-Positive Bacteria

(2012) Xiaoli Tian et al.   PLoS One

Disease Tolerance as a Defense Strategy

(2012) R. Medzhitov et al.   SCIENCE

Cell Receptors for Influenza a Viruses and the Innate Immune Response

(2012) Irene Ramos et al.   Frontiers in Microbiology

Recognition of Streptococcus pneumoniae by the innate immune system

(2011) Uwe Koppe et al.   CELLULAR MICROBIOLOGY

Favorable outcome after life-threatening meningococcal disease complicating influenza A(H1N1) infection

(2011) S. Legriel et al.   INFECTION

Synergistic stimulation of type I interferons during influenza virus coinfection promotes Streptococcus pneumoniae colonization in mice

(2011) Shigeki Nakamura et al.   JOURNAL OF CLINICAL INVESTIGATION

Coinfection with Mycobacterium tuberculosis and pandemic H1N1 influenza A virus in a patient with lung cancer

(2011) Che-Kim Tan et al.   JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION

Immunopathogenic and Antibacterial Effects of H3N2 Influenza A Virus PB1-F2 Map to Amino Acid Residues 62, 75, 79, and 82

(2011) I. V. Alymova et al.   JOURNAL OF VIROLOGY

Influenza A Inhibits Th17-Mediated Host Defense against Bacterial Pneumonia in Mice

(2010) A. Kudva et al.   JOURNAL OF IMMUNOLOGY

PB1-F2 Proteins from H5N1 and 20th Century Pandemic Influenza Viruses Cause Immunopathology

(2010) Julie L. McAuley et al.   PLoS Pathogens

Streptococcus pneumoniae nasopharyngeal colonization induces type I interferons and interferon-induced gene expression

(2009) Elizabeth A Joyce et al.   BMC GENOMICS

Cellular effectors mediating Th17-dependent clearance of pneumococcal colonization in mice

(2009) Zhe Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

Type I IFNs mediate development of postinfluenza bacterial pneumonia in mice

(2009) Arash Shahangian et al.   JOURNAL OF CLINICAL INVESTIGATION

The pneumococcus: why a commensal misbehaves

(2009) Jeffrey N. Weiser   JOURNAL OF MOLECULAR MEDICINE-JMM

Burden of disease caused by Haemophilus influenzae type b in children younger than 5 years: global estimates

(2009) James P Watt et al.   LANCET

Receptor-binding specificity of pandemic influenza A (H1N1) 2009 virus determined by carbohydrate microarray

(2009) Robert A Childs et al.   NATURE BIOTECHNOLOGY

Pathogenesis and Transmission of Swine-Origin 2009 A(H1N1) Influenza Virus in Ferrets

(2009) Vincent J. Munster et al.   SCIENCE

Transmission and Pathogenesis of Swine-Origin 2009 A(H1N1) Influenza Viruses in Ferrets and Mice

(2009) Taronna R. Maines et al.   SCIENCE

Emerging Concepts in the Immunopathogenesis of AIDS

(2008) Daniel C. Douek et al.   Annual Review of Medicine

The Pathology of Influenza Virus Infections

(2008) Jeffery K. Taubenberger et al.   Annual Review of Pathology-Mechanisms of Disease

The multifunctional NS1 protein of influenza A viruses

(2008) B. G. Hale et al.   JOURNAL OF GENERAL VIROLOGY

Predominant Role of Bacterial Pneumonia as a Cause of Death in Pandemic Influenza: Implications for Pandemic Influenza Preparedness

(2008) David M. Morens et al.   JOURNAL OF INFECTIOUS DISEASES

Infection with Human Metapneumovirus Predisposes Mice to Severe Pneumococcal Pneumonia

(2008) I. Kukavica-Ibrulj et al.   JOURNAL OF VIROLOGY

Inhibition of pulmonary antibacterial defense by interferon-γ during recovery from influenza infection

(2008) Keer Sun et al.   NATURE MEDICINE