Oseltamivir PK/PD Modeling and Simulation to Evaluate Treatment Strategies against Influenza-Pneumococcus Coinfection

A Drug-Disease Model Describing the Effect of Oseltamivir Neuraminidase Inhibition on Influenza Virus Progression

(2015) Mohamed A. Kamal et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A pharma perspective on the systems medicine and pharmacology of inflammation

(2015) Julio Lahoz-Beneytez et al.   MATHEMATICAL BIOSCIENCES

Modeling Influenza Virus Infection: A Roadmap for Influenza Research

(2015) Alessandro Boianelli et al.   Viruses-Basel

The effect of intravenous peramivir, compared with oral oseltamivir, on the outcome of post-influenza pneumococcal pneumonia in mice

(2014) Akitaka Tanaka et al.   ANTIVIRAL THERAPY

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

Viral kinetic modeling: state of the art

(2014) Laetitia Canini et al.   JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS

Effects of Aging on Influenza Virus Infection Dynamics

(2014) E. A. Hernandez-Vargas et al.   JOURNAL OF VIROLOGY

Antiviral combinations for severe influenza

(2014) Jake Dunning et al.   LANCET INFECTIOUS DISEASES

The co-pathogenesis of influenza viruses with bacteria in the lung

(2014) Jonathan A. McCullers   NATURE REVIEWS MICROBIOLOGY

Impact of Different Oseltamivir Regimens on Treating Influenza A Virus Infection and Resistance Emergence: Insights from a Modelling Study

(2014) Laetitia Canini et al.   PLoS Computational Biology

Model-based drug discovery: implementation and impact

(2013) Sandra A.G. Visser et al.   DRUG DISCOVERY TODAY

Assessing Mathematical Models of Influenza Infections Using Features of the Immune Response

(2013) Hana M. Dobrovolny et al.   PLoS One

Kinetics of Coinfection with Influenza A Virus and Streptococcus pneumoniae

(2013) Amber M. Smith et al.   PLoS Pathogens

Treatment With Neuraminidase Inhibitors for Critically Ill Patients With Influenza A (H1N1)pdm09

(2012) J. K. Louie et al.   CLINICAL INFECTIOUS DISEASES

Impact of Neuraminidase Inhibitor Treatment on Outcomes of Public Health Importance During the 2009-2010 Influenza A(H1N1) Pandemic: A Systematic Review and Meta-Analysis in Hospitalized Patients

(2012) S. G. Muthuri et al.   JOURNAL OF INFECTIOUS DISEASES

Type I Interferon Induction during Influenza Virus Infection Increases Susceptibility to Secondary Streptococcus pneumoniae Infection by Negative Regulation of    T Cells

(2012) W. Li et al.   JOURNAL OF VIROLOGY

Modeling Within-Host Dynamics of Influenza Virus Infection Including Immune Responses

(2012) Kasia A. Pawelek et al.   PLoS Computational Biology

A review of mathematical models of influenza A infections within a host or cell culture: lessons learned and challenges ahead

(2011) Catherine AA Beauchemin et al.   BMC PUBLIC HEALTH

Cluster of Oseltamivir-Resistant 2009 Pandemic Influenza A (H1N1) Virus Infections on a Hospital Ward among Immunocompromised Patients—North Carolina, 2009

(2011) Luke F. Chen et al.   JOURNAL OF INFECTIOUS DISEASES

Structural Basis for Streptococcus pneumoniae NanA Inhibition by Influenza Antivirals Zanamivir and Oseltamivir Carboxylate

(2011) Heinz Gut et al.   JOURNAL OF MOLECULAR BIOLOGY

Lethal Synergism of 2009 Pandemic H1N1 Influenza Virus and Streptococcus pneumoniae Coinfection Is Associated with Loss of Murine Lung Repair Responses

(2011) J. C. Kash et al.   mBio

Influenza Infection Leads to Increased Susceptibility to Subsequent Bacterial Superinfection by Impairing NK Cell Responses in the Lung

(2010) Cherrie-Lee Small et al.   JOURNAL OF IMMUNOLOGY

Neuraminidase inhibitors for treatment of human and avian strain influenza: A comparative modeling study

(2010) Hana M. Dobrovolny et al.   JOURNAL OF THEORETICAL BIOLOGY

Competitive Fitness of Oseltamivir-Sensitive and -Resistant Highly Pathogenic H5N1 Influenza Viruses in a Ferret Model

(2010) E. A. Govorkova et al.   JOURNAL OF VIROLOGY

Quantifying the Early Immune Response and Adaptive Immune Response Kinetics in Mice Infected with Influenza A Virus

(2010) H. Miao et al.   JOURNAL OF VIROLOGY

Population Modeling of Influenza A/H1N1 Virus Kinetics and Symptom Dynamics

(2010) L. Canini et al.   JOURNAL OF VIROLOGY

Type I IFNs mediate development of postinfluenza bacterial pneumonia in mice

(2009) Arash Shahangian et al.   JOURNAL OF CLINICAL INVESTIGATION

Sialic Acid: A Preventable Signal for Pneumococcal Biofilm Formation, Colonization, and Invasion of the Host

(2009) Claudia Trappetti et al.   JOURNAL OF INFECTIOUS DISEASES

Simulation and Prediction of the Adaptive Immune Response to Influenza A Virus Infection

(2009) H. Y. Lee et al.   JOURNAL OF VIROLOGY

Pharmacokinetics of High-Dose Oseltamivir in Healthy Volunteers

(2008) Y. Wattanagoon et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Surveillance for Neuraminidase Inhibitor Resistance among Human Influenza A and B Viruses Circulating Worldwide from 2004 to 2008

(2008) T. G. Sheu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Population Pharmacokinetics of Oseltamivir When Coadministered With Probenecid

(2008) Craig R. Rayner et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Predominant Role of Bacterial Pneumonia as a Cause of Death in Pandemic Influenza: Implications for Pandemic Influenza Preparedness

(2008) David M. Morens et al.   JOURNAL OF INFECTIOUS DISEASES

Treatment with Protein Synthesis Inhibitors Improves Outcomes of Secondary Bacterial Pneumonia after Influenza

(2008) Åsa Karlström et al.   JOURNAL OF INFECTIOUS DISEASES