Voltage-gated Na+ currents in human dorsal root ganglion neurons

Na V 1.7 as a pain target – From gene to pharmacology

(2017) Irina Vetter et al.   PHARMACOLOGY & THERAPEUTICS

Pharmacological characterisation of the highly NaV1.7 selective spider venom peptide Pn3a

(2017) Jennifer R. Deuis et al.   Scientific Reports

Group II mGluRs suppress hyperexcitability in mouse and human nociceptors

(2016) Steve Davidson et al.   PAIN

Subtype-Selective Small Molecule Inhibitors Reveal a Fundamental Role for Nav1.7 in Nociceptor Electrogenesis, Axonal Conduction and Presynaptic Release

(2016) Aristos J. Alexandrou et al.   PLoS One

Human Nav1.8: enhanced persistent and ramp currents contribute to distinct firing properties of human DRG neurons

(2015) Chongyang Han et al.   JOURNAL OF NEUROPHYSIOLOGY

Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis

(2015) Nanna B Finnerup et al.   LANCET NEUROLOGY

Inflammatory mediator-induced modulation of GABAA currents in human sensory neurons

(2015) X.-L. Zhang et al.   NEUROSCIENCE

Specific changes in conduction velocity recovery cycles of single nociceptors in a patient with erythromelalgia with the I848T gain-of-function mutation of Nav1.7

(2015) Barbara Namer et al.   PAIN

Endogenous opioids contribute to insensitivity to pain in humans and mice lacking sodium channel Nav1.7

(2015) Michael S. Minett et al.   Nature Communications

Post-translational modifications of voltage-gated sodium channels in chronic pain syndromes

(2015) Cedric J. Laedermann et al.   Frontiers in Pharmacology

Redistribution of voltage-gated sodium channels after nerve decompression contributes to relieve neuropathic pain in chronic constriction injury

(2014) To-Jung Tseng et al.   BRAIN RESEARCH

Molecular Signatures of Mouse TRPV1-Lineage Neurons Revealed by RNA-Seq Transcriptome Analysis

(2014) Samridhi C. Goswami et al.   JOURNAL OF PAIN

Voltage-Gated Sodium Channel Expression in Mouse DRG after SNI Leads to Re-Evaluation of Projections of Injured Fibers

(2014) Cédric J Laedermann et al.   Molecular Pain

Human sensory neurons: Membrane properties and sensitization by inflammatory mediators

(2014) Steve Davidson et al.   PAIN

Expression of sodium channel α subunits 1.1, 1.2 and 1.6 in rat hippocampus after kainic acid-induced epilepsy

(2013) Xin Qiao et al.   EPILEPSY RESEARCH

Expression of Nav1.7 in DRG Neurons Extends from Peripheral Terminals in the Skin to Central Preterminal Branches and Terminals in the Dorsal Horn

(2012) Joel A Black et al.   Molecular Pain

The NaV1.7 sodium channel: from molecule to man

(2012) Sulayman D. Dib-Hajj et al.   NATURE REVIEWS NEUROSCIENCE

Ionic Mechanisms Underlying Inflammatory Mediator-Induced Sensitization of Dural Afferents

(2010) A. H. Vaughn et al.   JOURNAL OF NEUROSCIENCE

Single-cell analysis of sodium channel expression in dorsal root ganglion neurons

(2010) Cojen Ho et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Presynaptic activity regulates Na+ channel distribution at the axon initial segment

(2010) Hiroshi Kuba et al.   NATURE

Nociceptor sensitization in pain pathogenesis

(2010) Michael S Gold et al.   NATURE MEDICINE

Serotonin Type 1D Receptors (5HT1DR) are Differentially Distributed in Nerve Fibres Innervating Craniofacial Tissues

(2008) AM Harriott et al.   CEPHALALGIA

ProTx-II, a Selective Inhibitor of NaV1.7 Sodium Channels, Blocks Action Potential Propagation in Nociceptors

(2008) W. A. Schmalhofer et al.   MOLECULAR PHARMACOLOGY

Trafficking and Cellular Distribution of Voltage-Gated Sodium Channels

(2008) Fiona S. Cusdin et al.   TRAFFIC