Presynaptic LRP4 promotes synapse number and function of excitatory CNS neurons

Wiring variations that enable and constrain neural computation in a sensory microcircuit

(2017) William F Tobin et al.   eLife

Synaptic circuitry of identified neurons in the antennal lobe of Drosophila melanogaster

(2016) Jürgen Rybak et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Protein-retention expansion microscopy of cells and tissues labeled using standard fluorescent proteins and antibodies

(2016) Paul W Tillberg et al.   NATURE BIOTECHNOLOGY

Lrp4 in astrocytes modulates glutamatergic transmission

(2016) Xiang-Dong Sun et al.   NATURE NEUROSCIENCE

A Role for Synaptic Input Distribution in a Dendritic Computation of Motion Direction in the Retina

(2016) Anna L. Vlasits et al.   NEURON

Unifying Views of Autism Spectrum Disorders: A Consideration of Autoregulatory Feedback Loops

(2016) Caitlin Mullins et al.   NEURON

Plasticity of Hippocampal Excitatory-Inhibitory Balance: Missing the Synaptic Control in the Epileptic Brain

(2016) Christian Bonansco et al.   NEURAL PLASTICITY

Maturation of active zone assembly byDrosophilaBruchpilot

(2016) Wernher Fouquet et al.   JOURNAL OF CELL BIOLOGY

Specification of synaptic connectivity by cell surface interactions

(2015) Joris de Wit et al.   NATURE REVIEWS NEUROSCIENCE

MADD-4/Punctin and Neurexin Organize C. elegans GABAergic Postsynapses through Neuroligin

(2015) Géraldine S. Maro et al.   NEURON

C. elegans Punctin Clusters GABAA Receptors via Neuroligin Binding and UNC-40/DCC Recruitment

(2015) Haijun Tu et al.   NEURON

Excitatory/Inhibitory Balance and Circuit Homeostasis in Autism Spectrum Disorders

(2015) Sacha B. Nelson et al.   NEURON

Expansion microscopy

(2015) F. Chen et al.   SCIENCE

On the Teneurin track: a new synaptic organization molecule emerges

(2015) Timothy J. Mosca   Frontiers in Cellular Neuroscience

Detection of In Situ Protein-protein Complexes at the Drosophila Larval Neuromuscular Junction Using Proximity Ligation Assay

(2015) Simon Wang et al.   Jove-Journal of Visualized Experiments

Lrp4 Domains Differentially Regulate Limb/Brain Development and Synaptic Plasticity

(2015) Theresa Pohlkamp et al.   PLoS One

Regulation of synaptic development and function by the Drosophila PDZ protein Dyschronic

(2014) J. E. C. Jepson et al.   DEVELOPMENT

Proteomic screening of glutamatergic mouse brain synaptosomes isolated by fluorescence activated sorting

(2014) Christoph Biesemann et al.   EMBO JOURNAL

LRP4 Is Critical for Neuromuscular Junction Maintenance

(2014) A. Barik et al.   JOURNAL OF NEUROSCIENCE

Double seronegative myasthenia gravis with low density lipoprotein-4 (LRP4) antibodies presenting with isolated ocular symptoms

(2014) Georgios Tsivgoulis et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Space–time wiring specificity supports direction selectivity in the retina

(2014) Jinseop S. Kim et al.   NATURE

C. elegans Punctin specifies cholinergic versus GABAergic identity of postsynaptic domains

(2014) Bérangère Pinan-Lucarré et al.   NATURE

Cell-type-Specific Labeling of Synapses In Vivo through Synaptic Tagging with Recombination

(2014) Yi Chen et al.   NEURON

Presynaptic and Postsynaptic Scaffolds

(2014) Noam E. Ziv et al.   NEUROSCIENTIST

Synaptic organization of the Drosophila antennal lobe and its regulation by the Teneurins

(2014) Timothy J Mosca et al.   eLife

Synaptic plasticity and cognitive function are disrupted in the absence of Lrp4

(2014) Andrea M Gomez et al.   eLife

Early Olfactory Processing in Drosophila: Mechanisms and Principles

(2013) Rachel I. Wilson   Annual Review of Neuroscience

Regulation of splicing by SR proteins and SR protein-specific kinases

(2013) Zhihong Zhou et al.   CHROMOSOMA

Genome Engineering of Drosophila with the CRISPR RNA-Guided Cas9 Nuclease

(2013) Scott J. Gratz et al.   GENETICS

Antibodies against low-density lipoprotein receptor–related protein 4 induce myasthenia gravis

(2013) Chengyong Shen et al.   JOURNAL OF CLINICAL INVESTIGATION

GABAergic Projection Neurons Route Selective Olfactory Inputs to Specific Higher-Order Neurons

(2013) Liang Liang et al.   NEURON

Molecular Profiling of Synaptic Vesicle Docking Sites Reveals Novel Proteins but Few Differences between Glutamatergic and GABAergic Synapses

(2013) Janina Boyken et al.   NEURON

Unbiased Discovery of Glypican as a Receptor for LRRTM4 in Regulating Excitatory Synapse Development

(2013) Joris de Wit et al.   NEURON

An LRRTM4-HSPG Complex Mediates Excitatory Synapse Development on Dentate Gyrus Granule Cells

(2013) Tabrez J. Siddiqui et al.   NEURON

Dedicated olfactory neurons mediating attraction behavior to ammonia and amines in Drosophila

(2013) S. Min et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glutamate is an inhibitory neurotransmitter in the Drosophila olfactory system

(2013) W. W. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein tyrosine phosphatases PTPδ, PTPσ, and LAR: presynaptic hubs for synapse organization

(2013) Hideto Takahashi et al.   TRENDS IN NEUROSCIENCES

LRP4 antibodies in serum and CSF from amyotrophic lateral sclerosis patients

(2013) John S. Tzartos et al.   Annals of Clinical and Translational Neurology

Synaptopathies: diseases of the synaptome

(2012) Seth GN Grant   CURRENT OPINION IN NEUROBIOLOGY

Ephrin regulation of synapse formation, function and plasticity

(2012) Martin Hruska et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Lrp4 is a retrograde signal for presynaptic differentiation at neuromuscular synapses

(2012) Norihiro Yumoto et al.   NATURE

Trans-synaptic Teneurin signalling in neuromuscular synapse organization and target choice

(2012) Timothy J. Mosca et al.   NATURE

Astrocyte glypicans 4 and 6 promote formation of excitatory synapses via GluA1 AMPA receptors

(2012) Nicola J. Allen et al.   NATURE

Selective control of inhibitory synapse development by Slitrk3-PTPδ trans-synaptic interaction

(2012) Hideto Takahashi et al.   NATURE NEUROSCIENCE

Cooperation of Syd-1 with Neurexin synchronizes pre- with postsynaptic assembly

(2012) David Owald et al.   NATURE NEUROSCIENCE

The role of agrin in synaptic development, plasticity and signaling in the central nervous system

(2012) Mathew P. Daniels   NEUROCHEMISTRY INTERNATIONAL

Distinct Roles of Muscle and Motoneuron LRP4 in Neuromuscular Junction Formation

(2012) Haitao Wu et al.   NEURON

Epilepsy: Ever-changing states of cortical excitability

(2012) R.A.B. Badawy et al.   NEUROSCIENCE

TheDrosophilaGene Disruption Project: Progress Using Transposons With Distinctive Site Specificities

(2011) Hugo J. Bellen et al.   GENETICS

Agrin Binds to the N-terminal Region of Lrp4 Protein and Stimulates Association between Lrp4 and the First Immunoglobulin-like Domain in Muscle-specific Kinase (MuSK)

(2011) Wei Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neocortical excitation/inhibition balance in information processing and social dysfunction

(2011) Ofer Yizhar et al.   NATURE

The Postsynaptic Organization of Synapses

(2011) M. Sheng et al.   Cold Spring Harbor Perspectives in Biology

The Q System: A Repressible Binary System for Transgene Expression, Lineage Tracing, and Mosaic Analysis

(2010) Christopher J. Potter et al.   CELL

Synaptic organizing complexes

(2010) Tabrez J Siddiqui et al.   CURRENT OPINION IN NEUROBIOLOGY

A Syd-1 homologue regulates pre- and postsynaptic maturation inDrosophila

(2010) David Owald et al.   JOURNAL OF CELL BIOLOGY

The nuclear import of Frizzled2-C by Importins-β11 and α2 promotes postsynaptic development

(2010) Timothy J Mosca et al.   NATURE NEUROSCIENCE

Characterization of dendritic spines in theDrosophilacentral nervous system

(2009) Florian Leiss et al.   Developmental Neurobiology

Leucine-rich repeat transmembrane proteins instruct discrete dendrite targeting in an olfactory map

(2009) Weizhe Hong et al.   NATURE NEUROSCIENCE

LRRTM2 Interacts with Neurexin1 and Regulates Excitatory Synapse Formation

(2009) Joris de Wit et al.   NEURON

Negative Regulation of Active Zone Assembly by a Newly Identified SR Protein Kinase

(2009) Ervin L. Johnson et al.   PLOS BIOLOGY

Bruchpilot in Ribbon-Like Axonal Agglomerates, Behavioral Defects, and Early Death in SRPK79D Kinase Mutants of Drosophila

(2009) Vanessa Nieratschker et al.   PLoS Genetics

Lrp4 Is a Receptor for Agrin and Forms a Complex with MuSK

(2008) Natalie Kim et al.   CELL

Clonal analysis of Drosophila antennal lobe neurons: diverse neuronal architectures in the lateral neuroblast lineage

(2008) S.-L. Lai et al.   DEVELOPMENT

Visualizing glutamatergic cell bodies and synapses inDrosophila larval and adult CNS

(2008) Richard W. Daniels et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Neuroligins and neurexins link synaptic function to cognitive disease

(2008) Thomas C. Südhof   NATURE

Lateral presynaptic inhibition mediates gain control in an olfactory circuit

(2008) Shawn R. Olsen et al.   NATURE

A Presynaptic Gain Control Mechanism Fine-Tunes Olfactory Behavior

(2008) Cory M. Root et al.   NEURON

LRP4 Serves as a Coreceptor of Agrin

(2008) Bin Zhang et al.   NEURON

Tools for neuroanatomy and neurogenetics in Drosophila

(2008) B. D. Pfeiffer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA