Distinct Akt phosphorylation states are required for insulin regulated Glut4 and Glut1-mediated glucose uptake

Disruption of Adipose Rab10-Dependent Insulin Signaling Causes Hepatic Insulin Resistance

(2016) Reema P. Vazirani et al.   DIABETES

Adipose tissue mTORC2 regulates ChREBP-driven de novo lipogenesis and hepatic glucose metabolism

(2016) Yuefeng Tang et al.   Nature Communications

Adenovirus Protein E4-ORF1 Activation of PI3 Kinase Reveals Differential Regulation of Downstream Effector Pathways in Adipocytes

(2016) Natasha Chaudhary et al.   Cell Reports

Development of a new model system to dissect isoform specific Akt signalling in adipocytes

(2015) Esi Kajno et al.   BIOCHEMICAL JOURNAL

Alternative Activation Mechanisms of Protein Kinase B Trigger Distinct Downstream Signaling Responses

(2015) Deborah Balzano et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Protein Kinase C Phosphorylation Motif in GLUT1 Affects Glucose Transport and is Mutated in GLUT1 Deficiency Syndrome

(2015) Eunice E. Lee et al.   MOLECULAR CELL

A Positive Feedback Loop between Akt and mTORC2 via SIN1 Phosphorylation

(2015) Guang Yang et al.   Cell Reports

Transcriptome Analysis of Individual Stromal Cell Populations Identifies Stroma-Tumor Crosstalk in Mouse Lung Cancer Model

(2015) Hyejin Choi et al.   Cell Reports

Phosphorylation of AKT: a Mutational Analysis.

(2015) Jonathan R. Hart et al.   Oncotarget

Glucose uptake in brown fat cells is dependent on mTOR complex 2–promoted GLUT1 translocation

(2014) Jessica M. Olsen et al.   JOURNAL OF CELL BIOLOGY

mTORC2 in the center of cancer metabolic reprogramming

(2014) Kenta Masui et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Myo1c binding to submembrane actin mediates insulin-induced tethering of GLUT4 vesicles

(2012) Shlomit Boguslavsky et al.   MOLECULAR BIOLOGY OF THE CELL

Signaling in Control of Cell Growth and Metabolism

(2012) P. S. Ward et al.   Cold Spring Harbor Perspectives in Biology

The Akt kinases: Isoform specificity in metabolism and cancer

(2011) Eva Gonzalez et al.   CELL CYCLE

GLUT1 expression in malignant tumors and its use as an immunodiagnostic marker

(2011) Kátia C. Carvalho et al.   Clinics

Targeting GLUT1 and the Warburg Effect in Renal Cell Carcinoma by Chemical Synthetic Lethality

(2011) D. A. Chan et al.   Science Translational Medicine

Fat Cell-Specific Ablation of Rictor in Mice Impairs Insulin-Regulated Fat Cell and Whole-Body Glucose and Lipid Metabolism

(2010) A. Kumar et al.   DIABETES

Targeting mTOR: prospects for mTOR complex 2 inhibitors in cancer therapy

(2010) C A Sparks et al.   ONCOGENE

Akt2 Is Required for Hepatic Lipid Accumulation in Models of Insulin Resistance

(2009) Karla F. Leavens et al.   Cell Metabolism

Variations in the requirement for v-SNAREs in GLUT4 trafficking in adipocytes

(2009) P. Zhao et al.   JOURNAL OF CELL SCIENCE

Insulin-modulated Akt subcellular localization determines Akt isoform-specific signaling

(2009) E. Gonzalez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of a Novel PH-Kinase Domain Interface in PKB/Akt Regulation: Structural Mechanism for Allosteric Inhibition

(2009) Véronique Calleja et al.   PLOS BIOLOGY

Use of Akt Inhibitor and a Drug-resistant Mutant Validates a Critical Role for Protein Kinase B/Akt in the Insulin-dependent Regulation of Glucose and System A Amino Acid Uptake

(2008) Charlotte J. Green et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PI3K/Akt: getting it right matters

(2008) T F Franke   ONCOGENE