Knockdown of SIRT1 Suppresses Bladder Cancer Cell Proliferation and Migration and Induces Cell Cycle Arrest and Antioxidant Response through FOXO3a-Mediated Pathways

miR-543 promotes gastric cancer cell proliferation by targeting SIRT1

(2016) Juan Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Metabolic phenotype of bladder cancer

(2016) Francesco Massari et al.   CANCER TREATMENT REVIEWS

Eccentric localization of catalase to protect chromosomes from oxidative damages during meiotic maturation in mouse oocytes

(2016) Yong Seok Park et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Carnosic acid protects starvation-induced SH-SY5Y cell death through Erk1/2 and Akt pathways, autophagy, and FoxO3a

(2016) Sachi Shibata et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION

Involvement of PI3K/Akt/FoxO3a and PKA/CREB Signaling Pathways in the Protective Effect of Fluoxetine Against Corticosterone-Induced Cytotoxicity in PC12 Cells

(2016) Bingqing Zeng et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Obesity Weighs down Memory through a Mechanism Involving the Neuroepigenetic Dysregulation of Sirt1

(2016) F. D. Heyward et al.   JOURNAL OF NEUROSCIENCE

Integrative Pathway Analysis of Metabolic Signature in Bladder Cancer: A Linkage to The Cancer Genome Atlas Project and Prediction of Survival

(2016) Friedrich-Carl von Rundstedt et al.   JOURNAL OF UROLOGY

Capsaicin Inhibits Multiple Bladder Cancer Cell Phenotypes by Inhibiting Tumor-Associated NADH Oxidase (tNOX) and Sirtuin1 (SIRT1)

(2016) Ming-Hung Lin et al.   MOLECULES

Circulating SIRT1 inversely correlates with epicardial fat thickness in patients with obesity

(2016) S. Mariani et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Diet-induced obesity and insulin resistance are associated with brown fat degeneration in SIRT1-deficient mice

(2016) Fen Xu et al.   Obesity

Decreased TRPM7 inhibits activities and induces apoptosis of bladder cancer cells via ERK1/2 pathway

(2016) Rui Cao et al.   Oncotarget

Glucose-Induced Oxidative Stress Reduces Proliferation in Embryonic Stem Cells via FOXO3A/β-Catenin-Dependent Transcription of p21cip1

(2016) Darcie L. McClelland Descalzo et al.   Stem Cell Reports

Oncogenic viral protein HPV E7 up-regulates the SIRT1 longevity protein in human cervical cancer cells

(2016) Simon J. Allison et al.   Aging-US

Association between SIRT1 Gene Polymorphisms and Breast Cancer in Egyptians

(2016) Sherine M. Rizk et al.   PLoS One

Simvastatin induces cell cycle arrest and inhibits proliferation of bladder cancer cells via PPARγ signalling pathway

(2016) Gang Wang et al.   Scientific Reports

Mining the bladder cancer-associated genes by an integrated strategy for the construction and analysis of differential co-expression networks

(2015) Su-Ping Deng et al.   BMC GENOMICS

Association of Genetic Variants of SIRT1 With Type 2 Diabetes Mellitus

(2015) Junfeng Han et al.   GENE EXPRESSION

Distinctive role of SIRT1 expression on tumor invasion and metastasis in breast cancer by molecular subtype

(2015) Yul Ri Chung et al.   HUMAN PATHOLOGY

Orphan nuclear receptor TLX functions as a potent suppressor of oncogene-induced senescence in prostate cancer via its transcriptional co-regulation of theCDKN1A(p21WAF1/CIP1) andSIRT1genes

(2015) Dinglan Wu et al.   JOURNAL OF PATHOLOGY

Over-expression of Sirt1 contributes to chemoresistance and indicates poor prognosis in serous epithelial ovarian cancer (EOC)

(2015) Ting Shuang et al.   MEDICAL ONCOLOGY

KEGG as a reference resource for gene and protein annotation

(2015) Minoru Kanehisa et al.   NUCLEIC ACIDS RESEARCH

Catalase Inhibits Ionizing Radiation-Induced Apoptosis in Hematopoietic Stem and Progenitor Cells

(2015) Xia Xiao et al.   STEM CELLS AND DEVELOPMENT

Expression/localization patterns of sirtuins (SIRT1, SIRT2, and SIRT7) during progression of cervical cancer and effects of sirtuin inhibitors on growth of cervical cancer cells

(2015) Sapna Singh et al.   TUMOR BIOLOGY

SIRT1 is involved in oncogenic signaling mediated by GPER in breast cancer

(2015) M F Santolla et al.   Cell Death & Disease

Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway

(2015) Shu-Feng Zhou et al.   Drug Design Development and Therapy

Induction of apoptosis and autophagy via sirtuin1- and PI3K/Akt/mTOR-mediated pathways by plumbagin in human prostate cancer cells

(2015) Shu-Feng Zhou et al.   Drug Design Development and Therapy

Cyclin-Dependent Kinase-2 as a Target for Cancer Therapy: Progress in the Development of CDK2 Inhibitors as Anti-Cancer Agents

(2014) Tahir Chohan et al.   CURRENT MEDICINAL CHEMISTRY

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Antiproliferative Effects of CDK4/6 Inhibition in CDK4-Amplified Human Liposarcoma In Vitro and In Vivo

(2014) Y.-X. Zhang et al.   MOLECULAR CANCER THERAPEUTICS

Dietary Blueberry and Bifidobacteria Attenuate Nonalcoholic Fatty Liver Disease in Rats by Affecting SIRT1-Mediated Signaling Pathway

(2014) Tingting Ren et al.   Oxidative Medicine and Cellular Longevity

Regulation of the Tumor Suppressor FOXO3 by the Thromboxane-A2 Receptors in Urothelial Cancer

(2014) Philip M. Sobolesky et al.   PLoS One

A novel crosstalk between BRCA1 and sirtuin 1 in ovarian cancer

(2014) Da Li et al.   Scientific Reports

Cyclin-dependent kinases

(2014) Marcos Malumbres   GENOME BIOLOGY

SIRT1 expression is associated with a poor prognosis, whereas DBC1 is associated with favorable outcomes in gastric cancer

(2014) Akira Noguchi et al.   Cancer Medicine

MiR-204 down regulates SIRT1 and reverts SIRT1-induced epithelial-mesenchymal transition, anoikis resistance and invasion in gastric cancer cells

(2013) Lihua Zhang et al.   BMC CANCER

PIASy mediates hypoxia-induced SIRT1 transcriptional repression and epithelial-to-mesenchymal transition in ovarian cancer cells

(2013) L. Sun et al.   JOURNAL OF CELL SCIENCE

Sirtuin deacylases: a molecular link between metabolism and immunity

(2013) Nicolas Preyat et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Epidemiology and Risk Factors of Urothelial Bladder Cancer

(2012) Maximilian Burger et al.   EUROPEAN UROLOGY

Resveratrol-mediated apoptosis of hodgkin lymphoma cells involves SIRT1 inhibition and FOXO3a hyperacetylation

(2012) Raffaele Frazzi et al.   INTERNATIONAL JOURNAL OF CANCER

SIRT1 induces EMT by cooperating with EMT transcription factors and enhances prostate cancer cell migration and metastasis

(2012) V Byles et al.   ONCOGENE

SIRT1 enhances matrix metalloproteinase-2 expression and tumor cell invasion in prostate cancer cells

(2012) Jenna D. Lovaas et al.   PROSTATE

Upsides and Downsides of Reactive Oxygen Species for Cancer: The Roles of Reactive Oxygen Species in Tumorigenesis, Prevention, and Therapy

(2011) Subash C. Gupta et al.   ANTIOXIDANTS & REDOX SIGNALING

Microarray-based bioinformatics analysis of osteoblasts on TiO2 nanotube layers

(2011) Weiqiang Yu et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Cyclin-dependent kinases 4 and 6 control tumor progression and direct glucose oxidation in the pentose cycle

(2011) Miriam Zanuy et al.   Metabolomics

Mammalian Sirtuins: Biological Insights and Disease Relevance

(2010) Marcia C. Haigis et al.   Annual Review of Pathology-Mechanisms of Disease