Diet-induced obesity and insulin resistance are associated with brown fat degeneration in SIRT1-deficient mice

Insulin resistance and impaired adipogenesis

(2015) Birgit Gustafson et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

SIRT1 enhances glucose tolerance by potentiating brown adipose tissue function

(2015) Marie Boutant et al.   Molecular Metabolism

SIRT1 Mediates the Effect of GLP-1 Receptor Agonist Exenatide on Ameliorating Hepatic Steatosis

(2014) Fen Xu et al.   DIABETES

Vascular rarefaction mediates whitening of brown fat in obesity

(2014) Ippei Shimizu et al.   JOURNAL OF CLINICAL INVESTIGATION

Myeloid SIRT1 regulates macrophage infiltration and insulin sensitivity in mice fed a high-fat diet

(2014) Sun-O Ka et al.   JOURNAL OF ENDOCRINOLOGY

Regulation of energy balance by inflammation: Common theme in physiology and pathology

(2014) Hui Wang et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

SIRT1 but not its increased expression is essential for lifespan extension in caloric-restricted mice

(2013) Evi M. Mercken et al.   AGING CELL

Adaptive thermogenesis in adipocytes: Is beige the new brown?

(2013) J. Wu et al.   GENES & DEVELOPMENT

Adipose tissue browning and metabolic health

(2013) Alexander Bartelt et al.   Nature Reviews Endocrinology

Brown Remodeling of White Adipose Tissue by SirT1-Dependent Deacetylation of Pparγ

(2012) Li Qiang et al.   CELL

Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human

(2012) Jun Wu et al.   CELL

The Implication of Brown Adipose Tissue for Humans

(2011) Eric Ravussin et al.   Annual Review of Nutrition

Increased Macrophage Migration Into Adipose Tissue in Obese Mice

(2011) D. Y. Oh et al.   DIABETES

Systemic SIRT1 insufficiency results in disruption of energy homeostasis and steroid hormone metabolism upon high-fat-diet feeding

(2011) Aparna Purushotham et al.   FASEB JOURNAL

Inflammatory links between obesity and metabolic disease

(2011) Carey N. Lumeng et al.   JOURNAL OF CLINICAL INVESTIGATION

Macrophages, Inflammation, and Insulin Resistance

(2010) Jerrold M. Olefsky et al.   Annual Review of Physiology

Lack of SIRT1 (Mammalian Sirtuin 1) Activity Leads to Liver Steatosis in the SIRT1+/−Mice: A Role of Lipid Mobilization and Inflammation

(2010) Fen Xu et al.   ENDOCRINOLOGY

Prevalence and Trends in Obesity Among US Adults, 1999-2008

(2010) Katherine M. Flegal   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Myeloid Deletion of SIRT1 Induces Inflammatory Signaling in Response to Environmental Stress

(2010) T. T. Schug et al.   MOLECULAR AND CELLULAR BIOLOGY

Reduced Adiposity and High-Fat Diet-Induced Adipose Inflammation in Mice Deficient for Phosphodiesterase 4B

(2009) Ren Zhang et al.   ENDOCRINOLOGY

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

(2009) Carles Cantó et al.   NATURE

SirT1 Gain of Function Increases Energy Efficiency and Prevents Diabetes in Mice

(2008) Alexander S. Banks et al.   Cell Metabolism

Metabolic Dysregulation and Adipose Tissue Fibrosis: Role of Collagen VI

(2008) T. Khan et al.   MOLECULAR AND CELLULAR BIOLOGY

Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes

(2008) Adilson Guilherme et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

SirT1 Regulates Energy Metabolism and Response to Caloric Restriction in Mice

(2008) Gino Boily et al.   PLoS One

Sirt1 protects against high-fat diet-induced metabolic damage

(2008) P. T. Pfluger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA