Anti-oxidant and immune-modulatory properties of sulfated alginate derivatives on human chondrocytes and macrophages

Sulfated alginate microspheres associate with factor H and dampen the inflammatory cytokine response

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Sulfated Hydrogel Matrices Direct Mitogenicity and Maintenance of Chondrocyte Phenotype through Activation of FGF Signaling

(2016) Ece Öztürk et al.   ADVANCED FUNCTIONAL MATERIALS

Low-grade inflammation as a key mediator of the pathogenesis of osteoarthritis

(2016) William H. Robinson et al.   Nature Reviews Rheumatology

Cartilage inflammation and degeneration is enhanced by pro-inflammatory (M1) macrophages in vitro , but not inhibited directly by anti-inflammatory (M2) macrophages

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Direct in vivo evidence of activated macrophages in human osteoarthritis

(2016) V.B. Kraus et al.   OSTEOARTHRITIS AND CARTILAGE

The Impact of Chain Length and Flexibility in the Interaction between Sulfated Alginates and HGF and FGF-2

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Biomaterial based modulation of macrophage polarization: a review and suggested design principles

(2015) Rukmani Sridharan et al.   Materials Today

Heparin-Like Properties of Sulfated Alginates with Defined Sequences and Sulfation Degrees

(2014) Øystein Arlov et al.   BIOMACROMOLECULES

Emerging regulators of the inflammatory process in osteoarthritis

(2014) Ru Liu-Bryan et al.   Nature Reviews Rheumatology

Human osteoarthritic synovium impacts chondrogenic differentiation of mesenchymal stem cells via macrophage polarisation state

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Porous Implants Modulate Healing and Induce Shifts in Local Macrophage Polarization in the Foreign Body Reaction

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Importance of synovitis in osteoarthritis: Evidence for the use of glycosaminoglycans against synovial inflammation

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Chondrocyte Culture in Three Dimensional Alginate Sulfate Hydrogels Promotes Proliferation While Maintaining Expression of Chondrogenic Markers

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The Roles of Mechanical Stresses in the Pathogenesis of Osteoarthritis

(2013) Joseph A. Buckwalter et al.   Cartilage

Role of inflammation in the pathogenesis of osteoarthritis: latest findings and interpretations

(2013) Jeremy Sokolove et al.   Therapeutic Advances in Musculoskeletal Disease

Artificial extracellular matrices composed of collagen I and high-sulfated hyaluronan promote phenotypic and functional modulation of human pro-inflammatory M1 macrophages

(2012) Sandra Franz et al.   Acta Biomaterialia

Alginate derivatization: A review of chemistry, properties and applications

(2012) Siddhesh N. Pawar et al.   BIOMATERIALS

Ribosomal Protein L13a as a Reference Gene for Human Bone Marrow-Derived Mesenchymal Stromal Cells During Expansion, Adipo-, Chondro-, and Osteogenesis

(2012) Deborah Studer et al.   TISSUE ENGINEERING PART C-METHODS

Macrophage phenotype as a predictor of constructive remodeling following the implantation of biologically derived surgical mesh materials

(2011) Bryan N. Brown et al.   Acta Biomaterialia

Alginate: Properties and biomedical applications

(2011) Kuen Yong Lee et al.   PROGRESS IN POLYMER SCIENCE

Quality of different chondroitin sulfate preparations in relation to their therapeutic activity

(2010) Nicola Volpi   JOURNAL OF PHARMACY AND PHARMACOLOGY

The role of synovitis in pathophysiology and clinical symptoms of osteoarthritis

(2010) Jérémie Sellam et al.   Nature Reviews Rheumatology

Role of proinflammatory cytokines in the pathophysiology of osteoarthritis

(2010) Mohit Kapoor et al.   Nature Reviews Rheumatology

Chondroitin sulfate in the treatment of osteoarthritis: from in vitro studies to clinical recommendations

(2010) Yves Henrotin et al.   Therapeutic Advances in Musculoskeletal Disease

Immunomodulatory and anti-inflammatory effects of chondroitin sulphate

(2009) Patrick du Souich et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Anti-inflammatory activity of chondroitin sulfate

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Antioxidant activity of sulfated polysaccharide fractions extracted from Laminaria japonica

(2007) Jing Wang et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES