HIV-I Nef inhibitors: a novel class of HIV-specific immune adjuvants in support of a cure

Engineering HIV-Resistant, Anti-HIV Chimeric Antigen Receptor T Cells

(2017) Malika Hale et al.   MOLECULAR THERAPY

HIV-specific CD8+ T cells and HIV eradication

(2016) R. Brad Jones et al.   JOURNAL OF CLINICAL INVESTIGATION

HIV Nef- and Notch1-dependent Endocytosis of ADAM17 Induces Vesicular TNF Secretion in Chronic HIV Infection

(2016) Christian Ostalecki et al.   EBioMedicine

HIV-1 Nef sequesters MHC-I intracellularly by targeting early stages of endocytosis and recycling

(2016) Brennan S. Dirk et al.   Scientific Reports

HIV-1 Nef: a master manipulator of the membrane trafficking machinery mediating immune evasion

(2015) Emily N. Pawlak et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

In VivoActivation of Human NK Cells by Treatment with an Interleukin-15 Superagonist Potently Inhibits AcuteIn VivoHIV-1 Infection in Humanized Mice

(2015) Kieran Seay et al.   JOURNAL OF VIROLOGY

Interaction with Cellular CD4 Exposes HIV-1 Envelope Epitopes Targeted by Antibody-Dependent Cell-Mediated Cytotoxicity

(2013) M. Veillette et al.   JOURNAL OF VIROLOGY

An interdomain binding site on HIV-1 Nef interacts with PACS-1 and PACS-2 on endosomes to down-regulate MHC-I

(2012) Jimmy D. Dikeakos et al.   MOLECULAR BIOLOGY OF THE CELL

The Identification of a Small Molecule Compound That Reduces HIV-1 Nef-Mediated Viral Infectivity Enhancement

(2011) Nopporn Chutiwitoonchai et al.   PLoS One

Small Molecule Inhibition of HIV-1–Induced MHC-I Down-Regulation Identifies a Temporally Regulated Switch in Nef Action

(2010) Jimmy D. Dikeakos et al.   MOLECULAR BIOLOGY OF THE CELL

Chemical Library Screens Targeting an HIV-1 Accessory Factor/Host Cell Kinase Complex Identify Novel Antiretroviral Compounds

(2009) Lori Emert-Sedlak et al.   ACS Chemical Biology

HIV-1 Nef Binds PACS-2 to Assemble a Multikinase Cascade That Triggers Major Histocompatibility Complex Class I (MHC-I) Down-regulation

(2008) Katelyn M. Atkins et al.   JOURNAL OF BIOLOGICAL CHEMISTRY