Small Molecule Inhibition of HIV-1–Induced MHC-I Down-Regulation Identifies a Temporally Regulated Switch in Nef Action

Lysine 144, a Ubiquitin Attachment Site in HIV-1 Nef, Is Required for Nef-Mediated CD4 Down-Regulation

(2014) Y.-J. Jin et al.   JOURNAL OF IMMUNOLOGY

Phosphatidylinositol-(4,5)-bisphosphate enables efficient secretion of HIV-1 Tat by infected T-cells

(2010) Fabienne Rayne et al.   EMBO JOURNAL

Chemical Library Screens Targeting an HIV-1 Accessory Factor/Host Cell Kinase Complex Identify Novel Antiretroviral Compounds

(2009) Lori Emert-Sedlak et al.   ACS Chemical Biology

At the crossroads of homoeostasis and disease: roles of the PACS proteins in membrane traffic and apoptosis

(2009) Robert T. Youker et al.   BIOCHEMICAL JOURNAL

Dys-regulated activation of a Src tyroine kinase Hck at the Golgi disturbsN-glycosylation of a cytokine receptor Fms

(2009) Ranya Hassan et al.   JOURNAL OF CELLULAR PHYSIOLOGY

An MHC-I Cytoplasmic Domain/HIV-1 Nef Fusion Protein Binds Directly to the μ Subunit of the AP-1 Endosomal Coat Complex

(2009) Rajendra Kumar Singh et al.   PLoS One

Induction of HIV-1 latency and reactivation in primary memory CD4+ T cells

(2008) A. Bosque et al.   BLOOD

Cellular Reservoirs of HIV-1 and their Role in Viral Persistence

(2008) Aikaterini Alexaki et al.   CURRENT HIV RESEARCH

HIV-1 Nef Binds PACS-2 to Assemble a Multikinase Cascade That Triggers Major Histocompatibility Complex Class I (MHC-I) Down-regulation

(2008) Katelyn M. Atkins et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PTEN posttranslational inactivation and hyperactivation of the PI3K/Akt pathway sustain primary T cell leukemia viability

(2008) Ana Silva et al.   JOURNAL OF CLINICAL INVESTIGATION

A traffic-activated Golgi-based signalling circuit coordinates the secretory pathway

(2008) Teodoro Pulvirenti et al.   NATURE CELL BIOLOGY

HIV-1 Nef Induces a Rab11-Dependent Routing of Endocytosed Immune Costimulatory Proteins CD80 and CD86 to the Golgi

(2008) Ashutosh Chaudhry et al.   TRAFFIC

HIV-1 Nef Targets MHC-I and CD4 for Degradation Via a Final Common β-COP–Dependent Pathway in T Cells

(2008) Malinda R. Schaefer et al.   PLoS Pathogens