Chronic Exposure to the Fusarium Mycotoxin Deoxynivalenol: Impact on Performance, Immune Organ, and Intestinal Integrity of Slow-Growing Chickens

The potential effects of antioxidant feed additives in mitigating the adverse effects of corn naturally contaminated with Fusarium mycotoxins on antioxidant systems in the intestinal mucosa, plasma, and liver in weaned pigs

(2016) Bich Van Le Thanh et al.   Mycotoxin Research

Deoxynivalenol induces apoptosis in chicken splenic lymphocytes via the reactive oxygen species-mediated mitochondrial pathway

(2015) Zhihua Ren et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Individual and combined effects of deoxynivalenol and zearalenone on mouse kidney

(2015) Zhen Liang et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

In vivo toxicity studies of fusarium mycotoxins in the last decade: A review

(2015) L. Escrivá et al.   FOOD AND CHEMICAL TOXICOLOGY

Deoxynivalenol in chicken feed alters the vaccinal immune response and clinical biochemical serum parameters but not the intestinal and carcass characteristics

(2015) K. Ghareeb et al.   JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION

Metabolism of Deoxynivalenol and Deepoxy-Deoxynivalenol in Broiler Chickens, Pullets, Roosters and Turkeys

(2015) Heidi Schwartz-Zimmermann et al.   Toxins

Oxidative stress-mediated cytotoxicity and metabolism of T-2 toxin and deoxynivalenol in animals and humans: an update

(2014) Qing-Hua Wu et al.   ARCHIVES OF TOXICOLOGY

Role of oxidative stress in Deoxynivalenol induced toxicity

(2014) Sakshi Mishra et al.   FOOD AND CHEMICAL TOXICOLOGY

Single and Combined Effects of Deoxynivalenol Mycotoxin and a Microbial Feed Additive on Lymphocyte DNA Damage and Oxidative Stress in Broiler Chickens

(2014) Wageha A. Awad et al.   PLoS One

Assessment of Multi-Mycotoxin Exposure in Southern Italy by Urinary Multi-Biomarker Determination

(2014) Michele Solfrizzo et al.   Toxins

Effect of Deoxynivalenol and Other Type B Trichothecenes on the Intestine: A Review

(2014) Philippe Pinton et al.   Toxins

Kinetics and metabolism of the Fusarium toxin deoxynivalenol in farm animals: Consequences for diagnosis of exposure and intoxication and carry over

(2013) Sven Dänicke et al.   FOOD AND CHEMICAL TOXICOLOGY

Metabolism, Distribution, and Excretion of Deoxynivalenol with Combined Techniques of Radiotracing, High-Performance Liquid Chromatography Ion Trap Time-of-Flight Mass Spectrometry, and Online Radiometric Detection

(2013) Dan Wan et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Deoxynivalenol Impairs Hepatic and Intestinal Gene Expression of Selected Oxidative Stress, Tight Junction and Inflammation Proteins in Broiler Chickens, but Addition of an Adsorbing Agent Shifts the Effects to the Distal Parts of the Small Intestine

(2013) Ann Osselaere et al.   PLoS One

The Association between Splenocyte Apoptosis and Alterations of Bax, Bcl-2 and Caspase-3 mRNA Expression, and Oxidative Stress Induced by Dietary Nickel Chloride in Broilers

(2013) Jianying Huang et al.   International Journal of Environmental Research and Public Health

The Toxicological Impacts of the Fusarium Mycotoxin, Deoxynivalenol, in Poultry Flocks with Special Reference to Immunotoxicity

(2013) Wageha Awad et al.   Toxins

From the Gut to the Brain: Journey and Pathophysiological Effects of the Food-Associated Trichothecene Mycotoxin Deoxynivalenol

(2013) Marc Maresca   Toxins

Toxicokinetic study and absolute oral bioavailability of deoxynivalenol, T-2 toxin and zearalenone in broiler chickens

(2012) Ann Osselaere et al.   FOOD AND CHEMICAL TOXICOLOGY

Efficacy and safety testing of mycotoxin-detoxifying agents in broilers following the European Food Safety Authority guidelines

(2012) A. Osselaere et al.   POULTRY SCIENCE

Effects of feed-borne Fusarium mycotoxins with or without yeast cell wall adsorbent on organ weight, serum biochemistry, and immunological parameters of broiler chickens

(2012) Z. Li et al.   POULTRY SCIENCE

Deoxynivalenol as a contaminant of broiler feed: Intestinal development, absorptive functionality, and metabolism of the mycotoxin

(2012) A. W. Yunus et al.   POULTRY SCIENCE

Deoxynivalenol as a contaminant of broiler feed: Effects on bird performance and response to common vaccines

(2012) A. W. Yunus et al.   POULTRY SCIENCE

Targets and Intracellular Signaling Mechanisms for Deoxynivalenol-Induced Ribosomal RNA Cleavage

(2012) Kaiyu He et al.   TOXICOLOGICAL SCIENCES

Mechanisms for ribotoxin-induced ribosomal RNA cleavage

(2012) Kaiyu He et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The toxicity of Fusarium mycotoxin deoxynivalenol in poultry feeding

(2012) W.A. AWAD et al.   WORLDS POULTRY SCIENCE JOURNAL

Effects of feeding wheat naturally contaminated with Fusarium mycotoxins on blood biochemistry and the effectiveness of dietary lignin treatment to alleviate mycotoxin adverse effects in broiler chickens

(2011) Katarína Klapácová et al.   ACTA VETERINARIA-BEOGRAD

The Impact of the Fusarium Mycotoxin Deoxynivalenol on the Health and Performance of Broiler Chickens

(2011) Wageha A. Awad et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A diet naturally contaminated with the Fusarium mycotoxin deoxynivalenol (DON) downregulates gene expression of glucose transporters in the intestine of broiler chickens

(2011) Wageha A. Awad et al.   Livestock Science

Developmental Profile of Claudin-3, -5, and -16 Proteins in the Epithelium of Chick Intestine

(2010) Ozkan Ozden et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Deoxynivalenol: mechanisms of action, human exposure, and toxicological relevance

(2010) James J. Pestka   ARCHIVES OF TOXICOLOGY

Isolation of deoxynivalenol-transforming bacteria from the chicken intestines using the approach of PCR-DGGE guided microbial selection

(2010) Hai Yu et al.   BMC MICROBIOLOGY

Feed contaminated with Fusarium toxins alter lymphocyte proliferation and apoptosis in primiparous sows during the perinatal period

(2010) T. Malovrh et al.   FOOD AND CHEMICAL TOXICOLOGY

Effects of dietary Fusarium mycotoxins on intestinal lymphocyte subset populations, cell proliferation and histological changes in avian lymphoid organs

(2010) C.K. Girish et al.   FOOD AND CHEMICAL TOXICOLOGY

Effects of chronic exposure of diets with reduced concentrations of aflatoxin and deoxynivalenol on growth and immune status of pigs1

(2010) A. C. Chaytor et al.   JOURNAL OF ANIMAL SCIENCE

The combination of deoxynivalenol and zearalenone at permitted feed concentrations causes serious physiological effects in young pigs

(2010) Feng Chen et al.   Journal of Veterinary Science

Induction of apoptotic lesions in liver and lymphoid tissues and modulation of cytokine mRNA expression by acute exposure to deoxynivalenol in piglets

(2010) Osamu Mikami et al.   Journal of Veterinary Science

Deoxynivalenol-Induced Proinflammatory Gene Expression: Mechanisms and Pathological Sequelae

(2010) James J. Pestka   Toxins

The Decrease of Relative Weight, Lesions, and Apoptosis of Bursa of Fabricius Induced by Excess Dietary Selenium in Chickens

(2009) Xi Peng et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Intestinal barrier function: Molecular regulation and disease pathogenesis

(2009) Katherine R. Groschwitz et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The food contaminant deoxynivalenol, decreases intestinal barrier permeability and reduces claudin expression

(2009) Philippe Pinton et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Mechanisms of deoxynivalenol-induced gene expression and apoptosis

(2008) J.J. Pestka   Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment

Ingestion of deoxynivalenol (DON) contaminated feed alters the pig vaccinal immune responses

(2008) Philippe Pinton et al.   TOXICOLOGY LETTERS

Both direct and indirect effects account for the pro-inflammatory activity of enteropathogenic mycotoxins on the human intestinal epithelium: Stimulation of interleukin-8 secretion, potentiation of interleukin-1β effect and increase in the transepithelial passage of commensal bacteria

(2007) Marc Maresca et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY