Myeloid Derived Hypoxia Inducible Factor 1-alpha Is Required for Protection against Pulmonary Aspergillus fumigatus Infection

Transmigrating Neutrophils Shape the Mucosal Microenvironment through Localized Oxygen Depletion to Influence Resolution of Inflammation

(2014) Eric L. Campbell et al.   IMMUNITY

CXCL5-secreting pulmonary epithelial cells drive destructive neutrophilic inflammation in tuberculosis

(2014) Geraldine Nouailles et al.   JOURNAL OF CLINICAL INVESTIGATION

Inflammatory Monocytes Orchestrate Innate Antifungal Immunity in the Lung

(2014) Vanessa Espinosa et al.   PLoS Pathogens

SEPT9_i1 is required for the association between HIF-1α and importin-α to promote efficient nuclear translocation

(2013) Maya Golan et al.   CELL CYCLE

Neutrophil cell surface receptors and their intracellular signal transduction pathways

(2013) Krisztina Futosi et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Monocyte- and Macrophage-Targeted NADPH Oxidase Mediates Antifungal Host Defense and Regulation of Acute Inflammation in Mice

(2013) M. J. Grimm et al.   JOURNAL OF IMMUNOLOGY

Complement C5 Activation during Influenza A Infection in Mice Contributes to Neutrophil Recruitment and Lung Injury

(2013) Cristiana C. Garcia et al.   PLoS One

HIF-1α Is Essential for Effective PMN Bacterial Killing, Antimicrobial Peptide Production and Apoptosis in Pseudomonas aeruginosa Keratitis

(2013) Elizabeth A. Berger et al.   PLoS Pathogens

Factors regulated by interferon gamma and hypoxia-inducible factor 1A contribute to responses that protect mice from Coccidioides immitis infection

(2012) Christopher H Woelk et al.   BMC MICROBIOLOGY

A CXCL1 Paracrine Network Links Cancer Chemoresistance and Metastasis

(2012) Swarnali Acharyya et al.   CELL

Immunity to fungi

(2012) Salomé LeibundGut-Landmann et al.   CURRENT OPINION IN IMMUNOLOGY

A new and clinically relevant murine model of solid-organ transplant aspergillosis

(2012) S. Herbst et al.   Disease Models & Mechanisms

Intrapulmonary Administration of Leukotriene B4 Augments Neutrophil Accumulation and Responses in the Lung to Klebsiella Infection in CXCL1 Knockout Mice

(2012) S. Batra et al.   JOURNAL OF IMMUNOLOGY

A new pharmacological agent (AKB-4924) stabilizes hypoxia inducible factor-1 (HIF-1) and increases skin innate defenses against bacterial infection

(2012) Cheryl Y. M. Okumura et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Hypoxia enhances innate immune activation to Aspergillus fumigatus through cell wall modulation

(2012) Kelly M. Shepardson et al.   MICROBES AND INFECTION

Hidden Killers: Human Fungal Infections

(2012) G. D. Brown et al.   Science Translational Medicine

Tracing Conidial Fate and Measuring Host Cell Antifungal Activity Using a Reporter of Microbial Viability in the Lung

(2012) Anupam Jhingran et al.   Cell Reports

Chemokine Receptor Ccr1 Drives Neutrophil-Mediated Kidney Immunopathology and Mortality in Invasive Candidiasis

(2012) Michail S. Lionakis et al.   PLoS Pathogens

Autophagy promotes survival of retinal ganglion cells after optic nerve axotomy in mice

(2011) N Rodríguez-Muela et al.   CELL DEATH AND DIFFERENTIATION

The mechanism of cell membrane ruffling relies on a phospholipase D2 (PLD2), Grb2 and Rac2 association

(2011) Madhu Mahankali et al.   CELLULAR SIGNALLING

At the core of survival: Autophagy delays the onset of both apoptotic and necrotic cell death in a model of ischemic cell injury

(2011) B. Loos et al.   EXPERIMENTAL CELL RESEARCH

Phagocyte responses towards Aspergillus fumigatus

(2011) Mike Hasenberg et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

In vivo Hypoxia and a Fungal Alcohol Dehydrogenase Influence the Pathogenesis of Invasive Pulmonary Aspergillosis

(2011) Nora Grahl et al.   PLoS Pathogens

The Small GTPase RacA Mediates Intracellular Reactive Oxygen Species Production, Polarized Growth, and Virulence in the Human Fungal Pathogen Aspergillus fumigatus

(2010) Haiyan Li et al.   EUKARYOTIC CELL

Changes in Apoptotic Gene Expression in Lymphocytes from Rheumatoid Arthritis and Systemic Lupus Erythematosus Patients Compared with Healthy Lymphocytes

(2010) Paul Eggleton et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Macrophage Migration Inhibitory Factor Counterregulates Dexamethasone-Mediated Suppression of Hypoxia-Inducible Factor-1  Function and Differentially Influences Human CD4+ T Cell Proliferation under Hypoxia

(2010) T. Gaber et al.   JOURNAL OF IMMUNOLOGY

An Intact Canonical NF- B Pathway Is Required for Inflammatory Gene Expression in Response to Hypoxia

(2010) S. F. Fitzpatrick et al.   JOURNAL OF IMMUNOLOGY

Acquired antifungal drug resistance inAspergillus fumigatus:epidemiology and detection

(2010) Susan Julie Howard et al.   MEDICAL MYCOLOGY

Platelet-Activating Factor Receptor Plays a Role in Lung Injury and Death Caused by Influenza A in Mice

(2010) Cristiana C. Garcia et al.   PLoS Pathogens

Production of Extracellular Traps against Aspergillus fumigatus In Vitro and in Infected Lung Tissue Is Dependent on Invading Neutrophils and Influenced by Hydrophobin RodA

(2010) Sandra Bruns et al.   PLoS Pathogens

Aspergillus fumigatus inhibits angiogenesis through the production of gliotoxin and other secondary metabolites

(2009) R. Ben-Ami et al.   BLOOD

Trends in invasive fungal infections, with emphasis on invasive aspergillosis

(2009) Z. Erjavec et al.   CLINICAL MICROBIOLOGY AND INFECTION

Essential Role for Neutrophils but not Alveolar Macrophages at Early Time Points followingAspergillus fumigatusInfection

(2009) Monica M. Mircescu et al.   JOURNAL OF INFECTIOUS DISEASES

Aspergillosis

(2009) Brahm H. Segal   NEW ENGLAND JOURNAL OF MEDICINE

HIF-1  regulates epithelial inflammation by cell autonomous NF B activation and paracrine stromal remodeling

(2008) M. Scortegagna et al.   BLOOD

Mitochondrial Autophagy Is an HIF-1-dependent Adaptive Metabolic Response to Hypoxia

(2008) Huafeng Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pharmacologic Augmentation of Hypoxia‐Inducible Factor–1α with Mimosine Boosts the Bactericidal Capacity of Phagocytes

(2008) Annelies S. Zinkernagel et al.   JOURNAL OF INFECTIOUS DISEASES

NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α

(2008) Jordi Rius et al.   NATURE

A Sterol-Regulatory Element Binding Protein Is Required for Cell Polarity, Hypoxia Adaptation, Azole Drug Resistance, and Virulence in Aspergillus fumigatus

(2008) Sven D. Willger et al.   PLoS Pathogens