A Novel Zn2-Cys6 Transcription Factor AtrR Plays a Key Role in an Azole Resistance Mechanism of Aspergillus fumigatus by Co-regulating cyp51A and cdr1B Expressions

Transcription Factor ADS-4 Regulates Adaptive Responses and Resistance to Antifungal Azole Stress

(2015) Kangji Wang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Azole Resistance inAspergillus fumigatus: Can We Retain the Clinical Use of Mold-Active Antifungal Azoles?

(2015) Paul E. Verweij et al.   CLINICAL INFECTIOUS DISEASES

First Detection of TR34 L98H and TR46 Y121F T289A Cyp51 Mutations in Aspergillus fumigatus Isolates in the United States

(2015) Nathan P. Wiederhold et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Functional characterization of PMT2, encoding a protein-O-mannosyltransferase, in the human pathogen Cryptococcus neoformans

(2014) Kiminori Shimizu et al.   FUNGAL GENETICS AND BIOLOGY

The role of AtfA and HOG MAPK pathway in stress tolerance in conidia of Aspergillus fumigatus

(2014) Daisuke Hagiwara et al.   FUNGAL GENETICS AND BIOLOGY

Azole, polyene and echinocandin MIC distributions for wild-type, TR34/L98H and TR46/Y121F/T289A Aspergillus fumigatus isolates in the Netherlands

(2014) J. van Ingen et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Whole-Genome Comparison of Aspergillus fumigatus Strains Serially Isolated from Patients with Aspergillosis

(2014) D. Hagiwara et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Antifungal susceptibility of Aspergillus fumigatus clinical isolates collected from various areas in Japan

(2014) Kazuyo Kikuchi et al.   JOURNAL OF INFECTION AND CHEMOTHERAPY

GliA in Aspergillus fumigatus is required for its tolerance to gliotoxin and affects the amount of extracellular and intracellular gliotoxin

(2014) D.-N. Wang et al.   MEDICAL MYCOLOGY

Zinc Finger Transcription Factors Displaced SREBP Proteins as the Major Sterol Regulators during Saccharomycotina Evolution

(2014) Sarah L. Maguire et al.   PLoS Genetics

Transcription Factor CCG-8 as a New Regulator in the Adaptation to Antifungal Azole Stress

(2013) Xianyun Sun et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Azole resistance in Aspergillus fumigatus

(2013) Edith Vermeulen et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Contributions of Aspergillus fumigatus ATP-Binding Cassette Transporter Proteins to Drug Resistance and Virulence

(2013) Sanjoy Paul et al.   EUKARYOTIC CELL

The cdr1B efflux transporter is associated with non-cyp51a-mediated itraconazole resistance in Aspergillus fumigatus 

(2013) Marcin G. Fraczek et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Azole-resistant Aspergillus fumigatus with the environmental TR46/Y121F/T289A mutation in India

(2013) A. Chowdhary et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Azole resistant Aspergillus fumigatus: An emerging problem

(2013) L. Lelièvre et al.   MEDECINE ET MALADIES INFECTIEUSES

Identification of ABC Transporter Genes of Fusarium graminearum with Roles in Azole Tolerance and/or Virulence

(2013) Ghada Abou Ammar et al.   PLoS One

Correlation between Triazole Treatment History and Susceptibility in Clinically Isolated Aspergillus fumigatus

(2012) Masato Tashiro et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Overexpression ofShCYP51BandShatrDin Sclerotinia homoeocarpa Isolates Exhibiting Practical Field Resistance to a Demethylation Inhibitor Fungicide

(2012) Jon Hulvey et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Transcriptomic and proteomic analyses of the Aspergillus fumigatus hypoxia response using an oxygen-controlled fermenter

(2012) Bridget M Barker et al.   BMC GENOMICS

Dsc Orthologs Are Required for Hypoxia Adaptation, Triazole Drug Responses, and Fungal Virulence in Aspergillus fumigatus

(2012) Sven D. Willger et al.   EUKARYOTIC CELL

CDR4 is the major contributor to azole resistance among four Pdr5p-like ABC transporters in Neurospora crassa

(2012) Yu Zhang et al.   Fungal Biology

High-level expression of cyp51B in azole-resistant clinical Aspergillus fumigatus isolates

(2012) A. Buied et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Coordination of hypoxia adaptation and iron homeostasis in human pathogenic fungi

(2012) Dawoon Chung et al.   Frontiers in Microbiology

Rapid Induction of Multiple Resistance Mechanisms in Aspergillus fumigatus during Azole Therapy: a Case Study and Review of the Literature

(2011) Simone M. T. Camps et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

SREBP-Dependent Triazole Susceptibility in Aspergillus fumigatus Is Mediated through Direct Transcriptional Regulation oferg11A(cyp51A)

(2011) Sara J. Blosser et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

SclR, a Basic Helix-Loop-Helix Transcription Factor, Regulates Hyphal Morphology and Promotes Sclerotial Formation in Aspergillus oryzae

(2011) Feng Jie Jin et al.   EUKARYOTIC CELL

SREBP Coordinates Iron and Ergosterol Homeostasis to Mediate Triazole Drug and Hypoxia Responses in the Human Fungal Pathogen Aspergillus fumigatus

(2011) Michael Blatzer et al.   PLoS Genetics

In vivo Hypoxia and a Fungal Alcohol Dehydrogenase Influence the Pathogenesis of Invasive Pulmonary Aspergillosis

(2011) Nora Grahl et al.   PLoS Pathogens

Regulation of the CgPdr1 Transcription Factor from the Pathogen Candida glabrata

(2010) Sanjoy Paul et al.   EUKARYOTIC CELL

Regulation of the Hypoxic Response in Candida albicans

(2010) John M. Synnott et al.   EUKARYOTIC CELL

Gain of Function Mutations in CgPDR1 of Candida glabrata Not Only Mediate Antifungal Resistance but Also Enhance Virulence

(2009) Sélène Ferrari et al.   PLoS Pathogens

A defect of LigD (human Lig4 homolog) for nonhomologous end joining significantly improves efficiency of gene-targeting in Aspergillus oryzae

(2008) Osamu Mizutani et al.   FUNGAL GENETICS AND BIOLOGY

Emergence of Azole Resistance in Aspergillus fumigatus and Spread of a Single Resistance Mechanism

(2008) Eveline Snelders et al.   PLOS MEDICINE

A Sterol-Regulatory Element Binding Protein Is Required for Cell Polarity, Hypoxia Adaptation, Azole Drug Resistance, and Virulence in Aspergillus fumigatus

(2008) Sven D. Willger et al.   PLoS Pathogens

Ergosterol biosynthesis pathway in Aspergillus fumigatus

(2007) Laura Alcazar-Fuoli et al.   STEROIDS