Genome-wide discovery of novel M1T1 group A streptococcal determinants important for fitness and virulence during soft-tissue infection

Genome-wide fitness analyses of the foodborne pathogen Campylobacter jejuni in in vitro and in vivo models

(2017) Stefan P. de Vries et al.   Scientific Reports

The Adc/Lmb System Mediates Zinc Acquisition in Streptococcus agalactiae and Contributes to Bacterial Growth and Survival

(2016) Pauline Moulin et al.   JOURNAL OF BACTERIOLOGY

Implementation and Data Analysis of Tn-seq, Whole-Genome Resequencing, and Single-Molecule Real-Time Sequencing for Bacterial Genetics

(2016) Peter E. Burby et al.   JOURNAL OF BACTERIOLOGY

Genome-wide Escherichia coli stress response and improved tolerance towards industrially relevant chemicals

(2016) Martin Holm Rau et al.   Microbial Cell Factories

Zn2+ Uptake in Streptococcus pyogenes: Characterization of adcA and lmb Null Mutants

(2016) Vittorio Tedde et al.   PLoS One

Genome-wide screen identifies host colonization determinants in a bacterial gut symbiont

(2016) J. Elijah Powell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Next-Generation High-Throughput Functional Annotation of Microbial Genomes

(2016) Ralph S. Baric et al.   mBio

Strain Dependent Genetic Networks for Antibiotic-Sensitivity in a Bacterial Pathogen with a Large Pan-Genome

(2016) Tim van Opijnen et al.   PLoS Pathogens

Modification of the CpsA Protein Reveals a Role in Alteration of the Streptococcus agalactiae Cell Envelope

(2015) Hannah M. Rowe et al.   INFECTION AND IMMUNITY

Phosphorylation Events in the Multiple Gene Regulator of Group A Streptococcus Significantly Influence Global Gene Expression and Virulence

(2015) Misu Sanson et al.   INFECTION AND IMMUNITY

Molecular epidemiology and genomics of group A Streptococcus

(2015) Debra E. Bessen et al.   INFECTION GENETICS AND EVOLUTION

Comparative Genomics of Streptococcus pyogenes M1 isolates differing in virulence and propensity to cause systemic infection in mice

(2015) Anne Fiebig et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Regulatory rewiring confers serotype-specific hyper-virulence in the human pathogen group AStreptococcus

(2015) Eric W. Miller et al.   MOLECULAR MICROBIOLOGY

Essential genome ofPseudomonas aeruginosain cystic fibrosis sputum

(2015) Keith H. Turner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Essential Genes in the Core Genome of the Human Pathogen Streptococcus pyogenes

(2015) Yoann Le Breton et al.   Scientific Reports

Comprehensive identification of virulence factors required for respiratory melioidosis using Tn-seq mutagenesis

(2015) Maria G. Gutierrez et al.   Frontiers in Cellular and Infection Microbiology

Current views of haemolytic streptococcal pathogenesis

(2014) Lionel K.K. Tan et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Role for Streptococcal Collagen-Like Protein 1 in M1T1 Group A Streptococcus Resistance to Neutrophil Extracellular Traps

(2014) Simon Döhrmann et al.   INFECTION AND IMMUNITY

An Antimicrobial Role for Zinc in Innate Immune Defense Against Group A Streptococcus

(2014) Cheryl-lynn Y. Ong et al.   JOURNAL OF INFECTIOUS DISEASES

Adhesin competence repressor (AdcR) from Streptococcus pyogenes controls adaptive responses to zinc limitation and contributes to virulence

(2014) Misu Sanson et al.   NUCLEIC ACIDS RESEARCH

Genes Contributing to Staphylococcus aureus Fitness in Abscess- and Infection-Related Ecologies

(2014) M. D. Valentino et al.   mBio

Protter: interactive protein feature visualization and integration with experimental proteomic data

(2013) Ulrich Omasits et al.   BIOINFORMATICS

Tn-Seq Analysis of Vibrio cholerae Intestinal Colonization Reveals a Role for T6SS-Mediated Antibacterial Activity in the Host

(2013) Yang Fu et al.   Cell Host & Microbe

Murine Vaginal Colonization Model for Investigating Asymptomatic Mucosal Carriage of Streptococcus pyogenes

(2013) Michael E. Watson et al.   INFECTION AND IMMUNITY

Genome-Wide Identification of Genes Required for Fitness of Group A Streptococcus in Human Blood

(2013) Yoann Le Breton et al.   INFECTION AND IMMUNITY

SMU.746-SMU.747, a Putative Membrane Permease Complex, Is Involved in Aciduricity, Acidogenesis, and Biofilm Formation in Streptococcus mutans

(2013) J. E. Krol et al.   JOURNAL OF BACTERIOLOGY

PTS phosphorylation of Mga modulates regulon expression and virulence in the group A streptococcus

(2013) Elise R. Hondorp et al.   MOLECULAR MICROBIOLOGY

Transposon insertion sequencing: a new tool for systems-level analysis of microorganisms

(2013) Tim van Opijnen et al.   NATURE REVIEWS MICROBIOLOGY

Identification of T6SS-dependent effector and immunity proteins by Tn-seq in Vibrio cholerae

(2013) T. G. Dong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Approaches to querying bacterial genomes with transposon-insertion sequencing

(2013) Lars Barquist et al.   RNA Biology

Gene Fitness Landscapes of Vibrio cholerae at Important Stages of Its Life Cycle

(2013) Heather D. Kamp et al.   PLoS Pathogens

Invasive Group A Streptococcal Disease

(2012) Andrew C. Steer et al.   DRUGS

A fine scale phenotype-genotype virulence map of a bacterial pathogen

(2012) T. van Opijnen et al.   GENOME RESEARCH

Functional Analysis of the CpsA Protein of Streptococcus agalactiae

(2012) B. R. Hanson et al.   JOURNAL OF BACTERIOLOGY

Conserved anchorless surface proteins as group A streptococcal vaccine candidates

(2012) Anna Henningham et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

The cell envelope-associated protein, LytR, regulates the cysteine protease SpeB in Streptococcus pyogenes

(2011) MASAAKI MINAMI et al.   APMIS

Importance of Toll-Like Receptor 9 in Host Defense against M1T1 Group A Streptococcus Infections

(2011) Annelies S. Zinkernagel et al.   Journal of Innate Immunity

Zinc uptake by Streptococcus pneumoniae depends on both AdcA and AdcAII and is essential for normal bacterial morphology and virulence

(2011) Lucie Bayle et al.   MOLECULAR MICROBIOLOGY

Integrative genomics viewer

(2011) James T Robinson et al.   NATURE BIOTECHNOLOGY

Molecular insight into invasive group A streptococcal disease

(2011) Jason N. Cole et al.   NATURE REVIEWS MICROBIOLOGY

Dispersal of Group A Streptococcal Biofilms by the Cysteine Protease SpeB Leads to Increased Disease Severity in a Murine Model

(2011) Kristie L. Connolly et al.   PLoS One

Dissection of the Molecular Basis for Hypervirulence of an In Vivo–Selected Phenotype of the Widely Disseminated M1T1 Strain of Group AStreptococcusBacteria

(2010) Rita G. Kansal et al.   JOURNAL OF INFECTIOUS DISEASES

Genetic Switch to Hypervirulence Reduces Colonization Phenotypes of the Globally Disseminated Group AStreptococcusM1T1 Clone

(2010) Andrew Hollands et al.   JOURNAL OF INFECTIOUS DISEASES

Microevolution of Group A Streptococci In Vivo: Capturing Regulatory Networks Engaged in Sociomicrobiology, Niche Adaptation, and Hypervirulence

(2010) Ramy K. Aziz et al.   PLoS One

Differential expression analysis for sequence count data

(2010) Simon Anders et al.   GENOME BIOLOGY

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Identifying Genetic Determinants Needed to Establish a Human Gut Symbiont in Its Habitat

(2009) Andrew L. Goodman et al.   Cell Host & Microbe

Simultaneous assay of every Salmonella Typhi gene using one million transposon mutants

(2009) G. C. Langridge et al.   GENOME RESEARCH

Population biology of the human restricted pathogen, Streptococcus pyogenes

(2009) Debra E. Bessen   INFECTION GENETICS AND EVOLUTION

Tn-seq: high-throughput parallel sequencing for fitness and genetic interaction studies in microorganisms

(2009) Tim van Opijnen et al.   NATURE METHODS

Inactivation of DltA Modulates Virulence Factor Expression in Streptococcus pyogenes

(2009) Kathleen H. Cox et al.   PLoS One

Tracking insertion mutants within libraries by deep sequencing and a genome-wide screen for Haemophilus genes required in the lung

(2009) J. D. Gawronski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fba, a novel fibronectin-binding protein from Streptococcus pyogenes, promotes bacterial entry into epithelial cells, and the fba gene is positively transcribed under the Mga regulator

(2003) Yutaka Terao et al.   MOLECULAR MICROBIOLOGY