mlh3 mutations in baker’s yeast alter meiotic recombination outcomes by increasing noncrossover events genome-wide

Modulating Crossover Frequency and Interference for Obligate Crossovers in Saccharomyces cerevisiae Meiosis

(2017) Parijat Chakraborty et al.   G3-Genes Genomes Genetics

The mismatch repair and meiotic recombination endonuclease Mlh1-Mlh3 is activated by polymer formation and can cleave DNA substrates in trans

(2017) Carol M. Manhart et al.   PLOS BIOLOGY

Distinct DNA-binding surfaces in the ATPase and linker domains of MutLγ determine its substrate specificities and exert separable functions in meiotic recombination and mismatch repair

(2017) Corentin Claeys Bouuaert et al.   PLoS Genetics

Concerted action of the MutLβ heterodimer and Mer3 helicase regulates the global extent of meiotic gene conversion

(2017) Yann Duroc et al.   eLife

Roles for mismatch repair family proteins in promoting meiotic crossing over

(2016) Carol M. Manhart et al.   DNA REPAIR

Eukaryotic Mismatch Repair in Relation to DNA Replication

(2015) Thomas A. Kunkel et al.   Annual Review of Genetics

Single-nucleotide polymorphism rs 175080 in the MLH3 gene and its relation to male infertility

(2015) Ourania Markandona et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Top3-Rmi1 DNA Single-Strand Decatenase Is Integral to the Formation and Resolution of Meiotic Recombination Intermediates

(2015) Hardeep Kaur et al.   MOLECULAR CELL

Pervasive and Essential Roles of the Top3-Rmi1 Decatenase Orchestrate Recombination and Facilitate Chromosome Segregation in Meiosis

(2015) Shangming Tang et al.   MOLECULAR CELL

Top3-Rmi1 Dissolve Rad51-Mediated D Loops by a Topoisomerase-Based Mechanism

(2015) Clare L. Fasching et al.   MOLECULAR CELL

Six polymorphisms in genes involved in DNA double-strand break repair and chromosome synapsis: association with male infertility

(2015) Xiaohui Zhang et al.   Systems Biology in Reproductive Medicine

MutS/MutL crystal structure reveals that the MutS sliding clamp loads MutL onto DNA

(2015) Flora S Groothuizen et al.   eLife

Variation in Crossover Frequencies Perturb Crossover Assurance Without Affecting Meiotic Chromosome Segregation in Saccharomyces cerevisiae

(2014) Gurukripa N. Krishnaprasad et al.   GENETICS

Mlh1-Mlh3, a Meiotic Crossover and DNA Mismatch Repair Factor, Is a Msh2-Msh3-stimulated Endonuclease

(2014) Maria V. Rogacheva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TheSaccharomyces cerevisiaeMlh1-Mlh3 Heterodimer Is an Endonuclease That Preferentially Binds to Holliday Junctions

(2014) Lepakshi Ranjha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Homologue engagement controls meiotic DNA break number and distribution

(2014) Drew Thacker et al.   NATURE

Controlling Meiotic Recombinational Repair – Specifying the Roles of ZMMs, Sgs1 and Mus81/Mms4 in Crossover Formation

(2014) Ashwini Oke et al.   PLoS Genetics

Structure of the MutLα C-terminal domain reveals how Mlh1 contributes to Pms1 endonuclease site

(2013) Emeric Gueneau et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Genetic Analysis of mlh3 Mutations Reveals Interactions Between Crossover Promoting Factors During Meiosis in Baker’s Yeast

(2013) Megan Sonntag Brown et al.   G3-Genes Genomes Genetics

Positive regulation of meiotic DNA double-strand break formation by activation of the DNA damage checkpoint kinase Mec1(ATR)

(2013) S. Gray et al.   Open Biology

Different Roles of Eukaryotic MutS and MutL Complexes in Repair of Small Insertion and Deletion Loops in Yeast

(2013) Nina V. Romanova et al.   PLoS Genetics

Delineation of Joint Molecule Resolution Pathways in Meiosis Identifies a Crossover-Specific Resolvase

(2012) Kseniya Zakharyevich et al.   CELL

Engineered Disulfide-forming Amino Acid Substitutions Interfere with a Conformational Change in the Mismatch Recognition Complex Msh2-Msh6 Required for Mismatch Repair

(2012) Victoria V. Hargreaves et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Unstructured Linker Arms of Mlh1–Pms1 Are Important for Interactions with DNA during Mismatch Repair

(2012) Aaron J. Plys et al.   JOURNAL OF MOLECULAR BIOLOGY

Regulatory Control of the Resolution of DNA Recombination Intermediates during Meiosis and Mitosis

(2011) Joao Matos et al.   CELL

Visualization of Eukaryotic DNA Mismatch Repair Reveals Distinct Recognition and Repair Intermediates

(2011) Hans Hombauer et al.   CELL

A Hierarchical Combination of Factors Shapes the Genome-wide Topography of Yeast Meiotic Recombination Initiation

(2011) Jing Pan et al.   CELL

Exploiting Spore-Autonomous Fluorescent Protein Expression to Quantify Meiotic Chromosome Behaviors inSaccharomyces cerevisiae

(2011) Drew Thacker et al.   GENETICS

Sustained and Rapid Chromosome Movements Are Critical for Chromosome Pairing and Meiotic Progression in Budding Yeast

(2011) Megan Sonntag Brown et al.   GENETICS

ReCombine: A Suite of Programs for Detection and Analysis of Meiotic Recombination in Whole-Genome Datasets

(2011) Carol M. Anderson et al.   PLoS One

Distinct Regulation of Mlh1p Heterodimers in Meiosis and Mitosis in Saccharomyces cerevisiae

(2010) V. E. Cotton et al.   GENETICS

Structure of the Endonuclease Domain of MutL: Unlicensed to Cut

(2010) Monica C. Pillon et al.   MOLECULAR CELL

Temporally and Biochemically Distinct Activities of Exo1 during Meiosis: Double-Strand Break Resection and Resolution of Double Holliday Junctions

(2010) Kseniya Zakharyevich et al.   MOLECULAR CELL

PCNA function in the activation and strand direction of MutL  endonuclease in mismatch repair

(2010) A. Pluciennik et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic Analysis of Baker's Yeast Msh4-Msh5 Reveals a Threshold Crossover Level for Meiotic Viability

(2010) K. T. Nishant et al.   PLoS Genetics

Global Analysis of the Meiotic Crossover Landscape

(2008) Stacy Y. Chen et al.   DEVELOPMENTAL CELL

Distinct Functions of MLH3 at Recombination Hot Spots in the Mouse

(2008) A. Svetlanov et al.   GENETICS

A Mutation in the Putative MLH3 Endonuclease Domain Confers a Defect in Both Mismatch Repair and Meiosis in Saccharomyces cerevisiae

(2008) K. T. Nishant et al.   GENETICS

The PMS2 Subunit of Human MutLα Contains a Metal Ion Binding Domain of the Iron-Dependent Repressor Protein Family

(2008) Jan Kosinski et al.   JOURNAL OF MOLECULAR BIOLOGY

Direct Visualization of Asymmetric Adenine Nucleotide-Induced Conformational Changes in MutLα

(2008) Elizabeth J. Sacho et al.   MOLECULAR CELL

High-resolution mapping of meiotic crossovers and non-crossovers in yeast

(2008) Eugenio Mancera et al.   NATURE