The co-existence of transcriptional activator and transcriptional repressor MEF2 complexes influences tumor aggressiveness

MEF2D Transduces Microenvironment Stimuli to ZEB1 to Promote Epithelial-Mesenchymal Transition and Metastasis in Colorectal Cancer

(2016) L. Su et al.   CANCER RESEARCH

Transformation by different oncogenes relies on specific metabolic adaptations

(2016) Paolo Peruzzo et al.   CELL CYCLE

Deregulated expression of HDAC9 in B cells promotes development of lymphoproliferative disease and lymphoma in mice

(2016) Veronica S. Gil et al.   Disease Models & Mechanisms

MEF2D-BCL9 Fusion Gene Is Associated With High-Risk Acute B-Cell Precursor Lymphoblastic Leukemia in Adolescents

(2016) Kyogo Suzuki et al.   JOURNAL OF CLINICAL ONCOLOGY

Transcriptome sequencing identifiesETV6-NTRK3as a gene fusion involved in GIST

(2016) Monica Brenca et al.   JOURNAL OF PATHOLOGY

Overexpression of HDAC9 promotes oral squamous cell carcinoma growth, regulates cell cycle progression, and inhibits apoptosis

(2016) Bhawna Rastogi et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Methyltransferase Dnmt3a upregulates HDAC9 to deacetylate the kinase TBK1 for activation of antiviral innate immunity

(2016) Xia Li et al.   NATURE IMMUNOLOGY

Functional interaction of histone deacetylase 5 (HDAC5) and lysine-specific demethylase 1 (LSD1) promotes breast cancer progression

(2016) C Cao et al.   ONCOGENE

Dynamic Phosphorylation of the Myocyte Enhancer Factor 2Cα1 Splice Variant Promotes Skeletal Muscle Regeneration and Hypertrophy

(2016) Fiorenza Baruffaldi et al.   STEM CELLS

Regulation of class IIa HDAC activities: it is not only matter of subcellular localization

(2016) Eros Di Giorgio et al.   Epigenomics

MEF2C and EBF1 Co-regulate B Cell-Specific Transcription

(2016) Nikki R. Kong et al.   PLoS Genetics

Exome Sequencing of Uterine Leiomyosarcomas Identifies Frequent Mutations in TP53, ATRX, and MED12

(2016) Netta Mäkinen et al.   PLoS Genetics

MEF2C regulates cortical inhibitory and excitatory synapses and behaviors relevant to neurodevelopmental disorders

(2016) Adam J Harrington et al.   eLife

Essential control of early B-cell development by Mef2 transcription factors

(2015) J. Herglotz et al.   BLOOD

Phosphorylation-dependent degradation of MEF2C contributes to regulate G2/M transition

(2015) Sara Badodi et al.   CELL CYCLE

The MEF2-HDAC axis controls proliferation of mammary epithelial cells and acini formation in vitro

(2015) A. Clocchiatti et al.   JOURNAL OF CELL SCIENCE

RBFox1-mediated RNA splicing regulates cardiac hypertrophy and heart failure

(2015) Chen Gao et al.   JOURNAL OF CLINICAL INVESTIGATION

The Control Operated by the Cell Cycle Machinery on MEF2 Stability Contributes to the Downregulation of CDKN1A and Entry into S Phase

(2015) Eros Di Giorgio et al.   MOLECULAR AND CELLULAR BIOLOGY

MEF2D Drives Photoreceptor Development through a Genome-wide Competition for Tissue-Specific Enhancers

(2015) Milena M. Andzelm et al.   NEURON

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

MEF2B mutations in non-Hodgkin lymphoma dysregulate cell migration by decreasing MEF2B target gene activation

(2015) Julia R. Pon et al.   Nature Communications

Overexpression of the Transcription Factor MEF2D in Hepatocellular Carcinoma Sustains Malignant Character by Suppressing G2-M Transition Genes

(2014) L. Ma et al.   CANCER RESEARCH

Poised chromatin in the mammalian germ line

(2014) B. J. Lesch et al.   DEVELOPMENT

MEF2 Transcription Factors Regulate Distinct Gene Programs in Mammalian Skeletal Muscle Differentiation

(2014) Nelsa L. Estrella et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alternative Splicing of MEF2C pre-mRNA Controls Its Activity in Normal Myogenesis and Promotes Tumorigenicity in Rhabdomyosarcoma Cells

(2014) Meiling Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Global MEF2 target gene analysis in cardiac and skeletal muscle reveals novel regulation of DUSP6 by p38MAPK-MEF2 signaling

(2014) Stephanie Wales et al.   NUCLEIC ACIDS RESEARCH

Myocyte enhancer factor 2C regulation of hepatocellular carcinoma via vascular endothelial growth factor and Wnt/β-catenin signaling

(2014) X L Bai et al.   ONCOGENE

Transcriptomic Analysis Unveils Correlations between Regulative Apoptotic Caspases and Genes of Cholesterol Homeostasis in Human Brain

(2014) Raffaella Picco et al.   PLoS One

Requirement of MEF2A, C, and D for skeletal muscle regeneration

(2014) N. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

KDM5 Interacts with Foxo to Modulate Cellular Levels of Oxidative Stress

(2014) Xingyin Liu et al.   PLoS Genetics

Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity

(2013) F. Ann Ran et al.   CELL

Tissue-specific splicing of a ubiquitously expressed transcription factor is essential for muscle differentiation

(2013) S. Sebastian et al.   GENES & DEVELOPMENT

MEF2 Is a Converging Hub for Histone Deacetylase 4 and Phosphatidylinositol 3-Kinase/Akt-Induced Transformation

(2013) Eros Di Giorgio et al.   MOLECULAR AND CELLULAR BIOLOGY

Loss of MEF2D expression inhibits differentiation and contributes to oncogenesis in rhabdomyosarcoma cells

(2013) Meiling Zhang et al.   Molecular Cancer

MEF2B mutations lead to deregulated expression of the oncogene BCL6 in diffuse large B cell lymphoma

(2013) Carol Y Ying et al.   NATURE IMMUNOLOGY

Modulation of lysine methylation in myocyte enhancer factor 2 during skeletal muscle cell differentiation

(2013) Jinmi Choi et al.   NUCLEIC ACIDS RESEARCH

Identifying targets for the restoration and reactivation of BRM

(2013) B Kahali et al.   ONCOGENE

New Therapeutic Targets in Soft Tissue Sarcoma

(2012) Elizabeth G. Demicco et al.   ADVANCES IN ANATOMIC PATHOLOGY

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

MEF2 negatively regulates learning-induced structural plasticity and memory formation

(2012) Christina J Cole et al.   NATURE NEUROSCIENCE

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

(2011) Bo Li et al.   BMC BIOINFORMATICS

Integrated Transcript and Genome Analyses Reveal NKX2-1 and MEF2C as Potential Oncogenes in T Cell Acute Lymphoblastic Leukemia

(2011) Irene Homminga et al.   CANCER CELL

Structure of p300 bound to MEF2 on DNA reveals a mechanism of enhanceosome assembly

(2011) Ju He et al.   NUCLEIC ACIDS RESEARCH

To repress or not to repress: This is the guardian's question

(2011) John L. Rinn et al.   TRENDS IN CELL BIOLOGY

Ubiquitin-dependent degradation of HDAC4, a new regulator of random cell motility

(2010) Nadia Cernotta et al.   MOLECULAR BIOLOGY OF THE CELL

Homing and invasiveness of MLL/ENL leukemic cells is regulated by MEF2C

(2009) M. Schwieger et al.   BLOOD

Soft tissue sarcomas with complex genomic profiles

(2009) Louis Guillou et al.   VIRCHOWS ARCHIV