Exome Sequencing of Uterine Leiomyosarcomas Identifies Frequent Mutations in TP53, ATRX, and MED12

Leiomyosarcoma With Alternative Lengthening of Telomeres Is Associated With Aggressive Histologic Features, Loss of ATRX Expression, and Poor Clinical Outcome

(2015) Jau-Yu Liau et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Discriminating somatic and germline mutations in tumor DNA samples without matching normals

(2015) Saskia Hiltemann et al.   GENOME RESEARCH

Alternative lengthening of telomeres and loss of ATRX are frequent events in pleomorphic and dedifferentiated liposarcomas

(2015) Jen-Chieh Lee et al.   MODERN PATHOLOGY

Alternative lengthening of telomeres renders cancer cells hypersensitive to ATR inhibitors

(2015) R. L. Flynn et al.   SCIENCE

Genomics of uterine leiomyomas: insights from high-throughput sequencing

(2014) Miika Mehine et al.   FERTILITY AND STERILITY

Lessons from the Cancer Genome

(2013) Levi A. Garraway et al.   CELL

Exomic landscape ofMED12mutation-negative and -positive uterine leiomyomas

(2013) Netta Mäkinen et al.   INTERNATIONAL JOURNAL OF CANCER

Incidence of uterine leiomyosarcoma and endometrial stromal sarcoma in Nordic countries: Results from NORDCAN and NOCCA databases

(2012) R. Koivisto-Korander et al.   MATURITAS

p53 mutations in cancer

(2012) Patricia A. J. Muller et al.   NATURE CELL BIOLOGY

Loss of ATRX, Genome Instability, and an Altered DNA Damage Response Are Hallmarks of the Alternative Lengthening of Telomeres Pathway

(2012) Courtney A. Lovejoy et al.   PLoS Genetics

Role of chemotherapy and biomolecular therapy in the treatment of uterine sarcomas

(2011) Martee L. Hensley   BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY

Function and regulation of the Mediator complex

(2011) Ronald C Conaway et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Altered Telomeres in Tumors with ATRX and DAXX Mutations

(2011) C. M. Heaphy et al.   SCIENCE

DAXX/ATRX, MEN1, and mTOR Pathway Genes Are Frequently Altered in Pancreatic Neuroendocrine Tumors

(2011) Y. Jiao et al.   SCIENCE

MED12, the Mediator Complex Subunit 12 Gene, Is Mutated at High Frequency in Uterine Leiomyomas

(2011) N. Makinen et al.   SCIENCE

Prognostic Factors in Early-Stage Leiomyosarcoma of the Uterus

(2010) Manuela Pelmus et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

Immunohistochemical studies on uterine carcinosarcoma, leiomyosarcoma, and endometrial stromal sarcoma: expression and prognostic importance of ten different markers

(2010) Riitta Koivisto-Korander et al.   TUMOR BIOLOGY

Uterine sarcomas in Norway. A histopathological and prognostic survey of a total population from 1970 to 2000 including 419 patients

(2009) Vera M Abeler et al.   HISTOPATHOLOGY

Prognostic factors and survival in 1396 patients with uterine leiomyosarcomas

(2008) Daniel S. Kapp et al.   CANCER

Genetic aberrations in soft tissue leiomyosarcoma

(2008) Jilong Yang et al.   CANCER LETTERS

Phase III randomised study to evaluate the role of adjuvant pelvic radiotherapy in the treatment of uterine sarcomas stages I and II: An European Organisation for Research and Treatment of Cancer Gynaecological Cancer Group Study (protocol 55874)

(2008) N.S. Reed et al.   EUROPEAN JOURNAL OF CANCER