A computational analysis of in vivo VEGFR activation by multiple co-expressed ligands

Regulation of Vegf signaling by natural and synthetic ligands

(2016) A. Rossi et al.   BLOOD

Flt-1 (VEGFR-1) coordinates discrete stages of blood vessel formation

(2016) John C. Chappell et al.   CARDIOVASCULAR RESEARCH

VEGFB/VEGFR1-Induced Expansion of Adipose Vasculature Counteracts Obesity and Related Metabolic Complications

(2016) Marius R. Robciuc et al.   Cell Metabolism

VEGF-B gene therapy inhibits doxorubicin-induced cardiotoxicity by endothelial protection

(2016) Markus Räsänen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Design principles for therapeutic angiogenic materials

(2016) Priscilla S. Briquez et al.   Nature Reviews Materials

Molecular mechanism matters: Benefits of mechanistic computational models for drug development

(2015) Lindsay E. Clegg et al.   PHARMACOLOGICAL RESEARCH

Molecular architecture of the ErbB2 extracellular domain homodimer

(2015) Shi Hu et al.   Oncotarget

Site-Specific Phosphorylation of VEGFR2 Is Mediated by Receptor Trafficking: Insights from a Computational Model

(2015) Lindsay Wendel Clegg et al.   PLoS Computational Biology

Antiangiogenic Actions of Vascular Endothelial Growth Factor-A 165 b, an Inhibitory Isoform of Vascular Endothelial Growth Factor-A, in Human Obesity

(2014) Doan T.M. Ngo et al.   CIRCULATION

NRP1 Presented in trans to the Endothelium Arrests VEGFR2 Endocytosis, Preventing Angiogenic Signaling and Tumor Initiation

(2014) Sina Koch et al.   DEVELOPMENTAL CELL

Maternal Serum Placental Growth Factor (PlGF) Isoforms 1 and 2 at 11-13 Weeks' Gestation in Normal and Pathological Pregnancies

(2014) Marta Nucci et al.   FETAL DIAGNOSIS AND THERAPY

An antiangiogenic isoform of VEGF-A contributes to impaired vascularization in peripheral artery disease

(2014) Ryosuke Kikuchi et al.   NATURE MEDICINE

Growth Factors Engineered for Super-Affinity to the Extracellular Matrix Enhance Tissue Healing

(2014) M. M. Martino et al.   SCIENCE

The Pivotal Role of Vascularization in Tissue Engineering

(2013) François A. Auger et al.   Annual Review of Biomedical Engineering

Extracellular regulation of VEGF: Isoforms, proteolysis, and vascular patterning

(2013) Prakash Vempati et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Therapeutic angiogenesis for revascularization in peripheral artery disease

(2013) Anna Grochot-Przeczek et al.   GENE

Proteolytic Processing Regulates Placental Growth Factor Activities

(2013) Daniel C. Hoffmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effect of Tumor Microenvironment on Tumor VEGF During Anti-VEGF Treatment: Systems Biology Predictions

(2013) Stacey D. Finley et al.   JNCI-Journal of the National Cancer Institute

PlGF: A Multitasking Cytokine with Disease-Restricted Activity

(2013) M. Dewerchin et al.   Cold Spring Harbor Perspectives in Medicine

Signal Transduction by Vascular Endothelial Growth Factor Receptors

(2013) S. Koch et al.   Cold Spring Harbor Perspectives in Medicine

Compartment Model Predicts VEGF Secretion and Investigates the Effects of VEGF Trap in Tumor-Bearing Mice

(2013) Stacey D. Finley et al.   Frontiers in Oncology

The discovery of placenta growth factor and its biological activity

(2012) Sandro De Falco   EXPERIMENTAL AND MOLECULAR MEDICINE

Expression of VEGF Receptors on Endothelial Cells in Mouse Skeletal Muscle

(2012) Princess I. Imoukhuede et al.   PLoS One

Signal transduction by vascular endothelial growth factor receptors

(2011) Sina Koch et al.   BIOCHEMICAL JOURNAL

An unexpected tail of VEGF and PlGF in pre-eclampsia

(2011) David O. Bates   BIOCHEMICAL SOCIETY TRANSACTIONS

Neuropilin-1 promotes VEGFR-2 trafficking through Rab11 vesicles thereby specifying signal output

(2011) K. Ballmer-Hofer et al.   BLOOD

Formation of VEGF isoform-specific spatial distributions governing angiogenesis: computational analysis

(2011) Prakash Vempati et al.   BMC Systems Biology

VEGF internalization is not required for VEGFR-2 phosphorylation in bioengineered surfaces with covalently linked VEGF

(2011) Sean M. Anderson et al.   Integrative Biology

Engineering the Growth Factor Microenvironment with Fibronectin Domains to Promote Wound and Bone Tissue Healing

(2011) M. M. Martino et al.   Science Translational Medicine

Overexpression of VEGF189 in breast cancer cells induces apoptosis via NRP1 under stress conditions

(2011) Nadejda Vintonenko et al.   Cell Adhesion & Migration

Computational Modeling of Interacting VEGF and Soluble VEGF Receptor Concentration Gradients

(2011) Yasmin L. Hashambhoy et al.   Frontiers in Physiology

VEGF and soluble VEGF receptor-1 (sFlt-1) distributions in peripheral arterial disease: an in silico model

(2010) Florence T. H. Wu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Increase of Plasma VEGF after Intravenous Administration of Bevacizumab Is Predicted by a Pharmacokinetic Model

(2010) M. O. Stefanini et al.   CANCER RESEARCH

Quantification and cell-to-cell variation of vascular endothelial growth factor receptors

(2010) P.I. Imoukhuede et al.   EXPERIMENTAL CELL RESEARCH

Anchorage of VEGF to the extracellular matrix conveys differential signaling responses to endothelial cells

(2010) Tom T. Chen et al.   JOURNAL OF CELL BIOLOGY

Quantifying the Proteolytic Release of Extracellular Matrix-Sequestered VEGF with a Computational Model

(2010) Prakash Vempati et al.   PLoS One

Systems biology of pro-angiogenic therapies targeting the VEGF system

(2010) Feilim Mac Gabhann et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

VEGF-A-stimulated signalling in endothelial cells via a dual receptor tyrosine kinase system is dependent on co-ordinated trafficking and proteolysis

(2009) Alexander F. Bruns et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

VEGFR1 receptor tyrosine kinase localization to the Golgi apparatus is calcium-dependent

(2009) Shweta Mittar et al.   EXPERIMENTAL CELL RESEARCH

Vascularization Strategies for Tissue Engineering

(2009) Michael Lovett et al.   TISSUE ENGINEERING PART B-REVIEWS

A compartment model of VEGF distribution in blood, healthy and diseased tissues

(2008) Marianne O Stefanini et al.   BMC Systems Biology

Systems Biology of Vascular Endothelial Growth Factors

(2008) Feilim Mac Gabhann et al.   MICROCIRCULATION