Monoamine oxidase B is elevated in Alzheimer disease neurons, is associated with γ-secretase and regulates neuronal amyloid β-peptide levels

Propargylamine Containing Compounds as Modulators of Proteolytic Cleavage of Amyloid Protein Precursor: Involvement of MAPK and PKC Activation

(2017) Orit Bar-Am et al.   JOURNAL OF ALZHEIMERS DISEASE

Diverging longitudinal changes in astrocytosis and amyloid PET in autosomal dominant Alzheimer’s disease

(2016) Elena Rodriguez-Vieitez et al.   BRAIN

Mitochondria-associated ER membranes and Alzheimer disease

(2016) Estela Area-Gomez et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Generation and deposition of Aβ43 by the virtually inactive presenilin‐1 L435F mutant contradicts the presenilin loss‐of‐function hypothesis of Alzheimer's disease

(2016) Benedikt Kretner et al.   EMBO Molecular Medicine

Alzheimer's disease

(2016) Philip Scheltens et al.   LANCET

Defeating Alzheimer's disease and other dementias: a priority for European science and society

(2016) Bengt Winblad et al.   LANCET NEUROLOGY

Super-resolution microscopy reveals γ-secretase at both sides of the neuronal synapse

(2016) Sophia Schedin-Weiss et al.   Acta Neuropathologica Communications

Proton myo-inositol cotransporter is a novel γ-secretase associated protein that regulates Aβ production without affecting Notch cleavage

(2015) Yasuhiro Teranishi et al.   FEBS Journal

Human brain proteins showing neuron-specific interactions with γ-secretase

(2015) Mitsuhiro Inoue et al.   FEBS Journal

An atomic structure of human γ-secretase

(2015) Xiao-chen Bai et al.   NATURE

Early astrocytosis in autosomal dominant Alzheimer’s disease measured in vivo by multi-tracer positron emission tomography

(2015) Michael Schöll et al.   Scientific Reports

Recent Developments in the Regulation of Monoamine Oxidase Form and Function: Is the Current Model Restricting Our Understanding of the Breadth of Contribution of Monoamine Oxidase to Brain [dys]Function?

(2013) Darrell D. Mousseau et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers

(2013) Clifford R Jack et al.   LANCET NEUROLOGY

Visualizing Active Enzyme Complexes Using a Photoreactive Inhibitor for Proximity Ligation – Application on γ-Secretase

(2013) Sophia Schedin-Weiss et al.   PLoS One

Trafficking and Proteolytic Processing of APP

(2013) C. Haass et al.   Cold Spring Harbor Perspectives in Medicine

Monoamine Oxidase Inhibitors as Neuroprotective Agents in Age-Dependent Neurodegenerative Disorders

(2012) Makoto Naoi et al.   CURRENT PHARMACEUTICAL DESIGN

Identification of Novel γ-Secretase-associated Proteins in Detergent-resistant Membranes from Brain

(2012) Ji-Yeun Hur et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evidence for Astrocytosis in Prodromal Alzheimer Disease Provided by 11C-Deuterium-L-Deprenyl: A Multitracer PET Paradigm Combining 11C-Pittsburgh Compound B and 18F-FDG

(2012) S. F. Carter et al.   JOURNAL OF NUCLEAR MEDICINE

Identification of two novel synaptic γ-secretase associated proteins that affect amyloid β-peptide levels without altering Notch processing

(2012) Susanne Frykman et al.   NEUROCHEMISTRY INTERNATIONAL

Analysis of microdissected human neurons by a sensitive ELISA reveals a correlation between elevated intracellular concentrations of Aβ42 and Alzheimer’s disease neuropathology

(2010) Masakazu Hashimoto et al.   ACTA NEUROPATHOLOGICA

Preparation and characterization of toxic Aβ aggregates for structural and functional studies in Alzheimer's disease research

(2010) Asad Jan et al.   Nature Protocols

Superresolution Imaging of Chemical Synapses in the Brain

(2010) Adish Dani et al.   NEURON

Amyloid β-peptide levels in laser capture microdissected cornu ammonis 1 pyramidal neurons of Alzheimerʼs brain

(2010) Mikio Aoki et al.   NEUROREPORT

Affinity pulldown of γ-secretase and associated proteins from human and rat brain

(2009) Yasuhiro Teranishi et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Primary support cultures of hippocampal and substantia nigra neurons

(2009) Thomas Fath et al.   Nature Protocols

Function, regulation and therapeutic properties of β-secretase (BACE1)

(2009) Michael Willem et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Intramembrane Proteolysis by γ-Secretase

(2008) Harald Steiner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY