Methotraxate-Loaded Hybrid Nanoconstructs Target Vascular Lesions and Inhibit Atherosclerosis Progression in ApoE−/− Mice

Targeted Interleukin-10 Nanotherapeutics Developed with a Microfluidic Chip Enhance Resolution of Inflammation in Advanced Atherosclerosis

(2016) Nazila Kamaly et al.   ACS Nano

Imaging Atherosclerosis

(2016) Jason M. Tarkin et al.   CIRCULATION RESEARCH

Multifunctional Nanoparticles Facilitate Molecular Targeting and miRNA Delivery to Inhibit Atherosclerosis in ApoE–/– Mice

(2015) Azadeh Kheirolomoom et al.   ACS Nano

Radiolabeled Polymeric Nanoconstructs Loaded with Docetaxel and Curcumin for Cancer Combinatorial Therapy and Nuclear Imaging

(2015) Cinzia Stigliano et al.   ADVANCED FUNCTIONAL MATERIALS

Methotrexate-mediated activation of an AMPK-CREB-dependent pathway: a novel mechanism for vascular protection in chronic systemic inflammation

(2015) C C Thornton et al.   ANNALS OF THE RHEUMATIC DISEASES

Use of Combined Chemotherapy with Etoposide and Methotrexate, both Associated to Lipid Nanoemulsions for Atherosclerosis Treatment in Cholesterol-fed Rabbits

(2015) Antonio C. A. Leite et al.   CARDIOVASCULAR DRUGS AND THERAPY

Anti-inflammatory and immune-modulatory therapies for preventing atherosclerotic cardiovascular disease

(2015) Tomoya Yamashita et al.   Journal of Cardiology

Hybrid nanoparticles improve targeting to inflammatory macrophages through phagocytic signals

(2015) Vaishali Bagalkot et al.   JOURNAL OF CONTROLLED RELEASE

Inflammation and plaque vulnerability

(2015) G. K. Hansson et al.   JOURNAL OF INTERNAL MEDICINE

The Myth of the “Vulnerable Plaque”

(2015) Armin Arbab-Zadeh et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Magnetic resonance imaging-based computational modelling of blood flow and nanomedicine deposition in patients with peripheral arterial disease

(2015) S. S. Hossain et al.   Journal of the Royal Society Interface

Anti-inflammatory therapies for atherosclerosis

(2015) Magnus Bäck et al.   Nature Reviews Cardiology

Targeted nanoparticles containing the proresolving peptide Ac2-26 protect against advanced atherosclerosis in hypercholesterolemic mice

(2015) Gabrielle Fredman et al.   Science Translational Medicine

Probing nanoparticle translocation across the permeable endothelium in experimental atherosclerosis

(2014) Y. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Positron Emitting Magnetic Nanoconstructs for PET/MR Imaging

(2014) Santosh Aryal et al.   Small

Rationale and design of the Cardiovascular Inflammation Reduction Trial: A test of the inflammatory hypothesis of atherothrombosis

(2013) Brendan M. Everett et al.   AMERICAN HEART JOURNAL

Vascular deposition patterns for nanoparticles in an inflamed patient-specific arterial tree

(2013) Shaolie S. Hossain et al.   Biomechanics and Modeling in Mechanobiology

Rosiglitazone-loaded nanospheres for modulating macrophage-specific inflammation in obesity

(2013) Daniele Di Mascolo et al.   JOURNAL OF CONTROLLED RELEASE

Local proliferation dominates lesional macrophage accumulation in atherosclerosis

(2013) Clinton S Robbins et al.   NATURE MEDICINE

Inflammation in Atherosclerosis

(2012) Peter Libby   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Dietary curcumin inhibits atherosclerosis by affecting the expression of genes involved in leukocyte adhesion and transendothelial migration

(2012) Dilek Coban et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Molecular Imaging with Theranostic Nanoparticles

(2011) Jesse V. Jokerst et al.   ACCOUNTS OF CHEMICAL RESEARCH

Interleukin-1β inhibition and the prevention of recurrent cardiovascular events: Rationale and Design of the Canakinumab Anti-inflammatory Thrombosis Outcomes Study (CANTOS)

(2011) Paul M Ridker et al.   AMERICAN HEART JOURNAL

Systematic Review and Meta-Analysis of Methotrexate Use and Risk of Cardiovascular Disease

(2011) Renata Micha et al.   AMERICAN JOURNAL OF CARDIOLOGY

Targeting therapeutics to the vascular wall in atherosclerosis–Carrier size matters

(2011) Phapanin Charoenphol et al.   ATHEROSCLEROSIS

Cell-mediated drug delivery

(2011) Elena V Batrakova et al.   Expert Opinion on Drug Delivery

Treatment With Methotrexate Inhibits Atherogenesis in Cholesterol-Fed Rabbits

(2011) Adriana Bulgarelli et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Atherosclerosis: current pathogenesis and therapeutic options

(2011) Christian Weber et al.   NATURE MEDICINE

Cardiovascular safety of biologic therapies for the treatment of RA

(2011) Jeffrey D. Greenberg et al.   Nature Reviews Rheumatology

Nanoparticle-based theranostic agents

(2010) Jin Xie et al.   ADVANCED DRUG DELIVERY REVIEWS

Advances in individual prediction of methotrexate toxicity: a review

(2009) Kjeld Schmiegelow   BRITISH JOURNAL OF HAEMATOLOGY

Macrophages: Promising Targets for the Treatment of Atherosclerosis

(2009) Heather Wilson et al.   Current Vascular Pharmacology

The effect of methotrexate on cardiovascular disease in patients with rheumatoid arthritis: a systematic literature review

(2009) S. L. Westlake et al.   RHEUMATOLOGY

Self-Assembled Lipid−Polymer Hybrid Nanoparticles: A Robust Drug Delivery Platform

(2008) Liangfang Zhang et al.   ACS Nano

Hemodynamic shear stress and the endothelium in cardiovascular pathophysiology

(2008) Peter F Davies   Nature clinical practice. Cardiovascular medicine

Design maps for nanoparticles targeting the diseased microvasculature

(2007) Paolo Decuzzi et al.   BIOMATERIALS

Nanoparticle PET-CT Imaging of Macrophages in Inflammatory Atherosclerosis

(2007) Matthias Nahrendorf et al.   CIRCULATION