Normalization of adiponectin concentrations by leptin replacement in ob/ob mice is accompanied by reductions in systemic oxidative stress and inflammation

The ominous triad of adipose tissue dysfunction: inflammation, fibrosis, and impaired angiogenesis

(2017) Clair Crewe et al.   JOURNAL OF CLINICAL INVESTIGATION

Muscle-specific overexpression of AdipoR1 or AdipoR2 gives rise to common and discrete local effects whilst AdipoR2 promotes additional systemic effects

(2017) Sahar Keshvari et al.   Scientific Reports

Leptin dose-dependently decreases atherosclerosis by attenuation of hypercholesterolemia and induction of adiponectin

(2016) Annett Hoffmann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Leptin Within the Subphysiological to Physiological Range Dose Dependently Improves Male Reproductive Function in an Obesity Mouse Model

(2016) Annett Hoffmann et al.   ENDOCRINOLOGY

Impact of weight loss induced by gastric bypass or caloric restriction on oxidative stress and genomic damage in obese Zucker rats

(2016) Ezgi Eyluel Bankoglu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Leptin Induces Oxidative Stress Through Activation of NADPH Oxidase in Renal Tubular Cells: Antioxidant Effect of L-Carnitine

(2016) Antonio J. Blanca et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Management of obesity

(2016) George A Bray et al.   LANCET

Serum Amyloid A3 Gene Expression in Adipocytes is an Indicator of the Interaction with Macrophages

(2016) Yohei Sanada et al.   Scientific Reports

Acylated and desacyl ghrelin are associated with hepatic lipogenesis, β-oxidation and autophagy: role in NAFLD amelioration after sleeve gastrectomy in obese rats

(2016) Silvia Ezquerro et al.   Scientific Reports

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(2016)   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

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(2016)   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Differential effects of leptin on adiponectin expression with weight gain versus obesity

(2015) P Singh et al.   INTERNATIONAL JOURNAL OF OBESITY

From leptin to other adipokines in health and disease: Facts and expectations at the beginning of the 21st century

(2015) Matthias Blüher et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Melatonin reduces obesity and restores adipokine patterns and metabolism in obese ( ob/ob ) mice

(2015) Gaia Favero et al.   NUTRITION RESEARCH

Potent effects of dioscin against obesity in mice

(2015) Min Liu et al.   Scientific Reports

Leptin administration restores the altered adipose and hepatic expression of aquaglyceroporins improving the non-alcoholic fatty liver of ob/ob mice

(2015) Amaia Rodríguez et al.   Scientific Reports

Leptin administration alleviates ischemic brain injury in mice by reducing oxidative stress and subsequent neuronal apoptosis

(2015) Jin-Ying Zhang et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Increased Cardiometabolic Risk Factors and Inflammation in Adipose Tissue in Obese Subjects Classified as Metabolically Healthy

(2014) Javier Gómez-Ambrosi et al.   DIABETES CARE

Adiposity induces lethal cytokine storm after systemic administration of stimulatory immunotherapy regimens in aged mice

(2014) Annie Mirsoian et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Osteopontin Deletion Prevents the Development of Obesity and Hepatic Steatosis via Impaired Adipose Tissue Matrix Remodeling and Reduced Inflammation and Fibrosis in Adipose Tissue and Liver in Mice

(2014) Andoni Lancha et al.   PLoS One

Obesity: The Gateway to Ill Health - an EASO Position Statement on a Rising Public Health, Clinical and Scientific Challenge in Europe

(2013) Gema Frühbeck et al.   Obesity Facts

The role of adiponectin signaling in metabolic syndrome and cancer

(2013) Michael P. Scheid et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Adipose tissue immunity and cancer

(2013) Victoria Catalán et al.   Frontiers in Physiology

Leptin is key to peroxynitrite-mediated oxidative stress and Kupffer cell activation in experimental non-alcoholic steatohepatitis

(2012) Saurabh Chatterjee et al.   JOURNAL OF HEPATOLOGY

Peripheral signalling involved in energy homeostasis control

(2012) Andoni Lancha et al.   NUTRITION RESEARCH REVIEWS

Aquaglyceroporins serve as metabolic gateways in adiposity and insulin resistance control

(2011) Amaia Rodríguez et al.   CELL CYCLE

Central Leptin Signaling Is Required to Normalize Myocardial Fatty Acid Oxidation Rates in Caloric-Restricted ob/ob Mice

(2011) C. Sloan et al.   DIABETES

Leptin protects cardiomyocytes from serum-deprivation-induced apoptosis by increasing anti-oxidant defence

(2010) Juan Zheng et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Leptin Administration Downregulates the Increased Expression Levels of Genes Related to Oxidative Stress and Inflammation in the Skeletal Muscle ofob/obMice

(2010) Neira Sáinz et al.   MEDIATORS OF INFLAMMATION

Leptin Administration Favors Muscle Mass Accretion by Decreasing FoxO3a and Increasing PGC-1α in ob/ob Mice

(2009) Neira Sáinz et al.   PLoS One

Loss of resistin ameliorates hyperlipidemia and hepatic steatosis in leptin-deficient mice

(2008) Neel S. Singhal et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

URB is abundantly expressed in adipose tissue and dysregulated in obesity

(2008) Takuya Okada et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Adipose tissue gene expression profiles in ob/ob mice treated with leptin

(2008) Wei Zhang et al.   LIFE SCIENCES

Mechanisms of Leptin Action and Leptin Resistance

(2007) Martin G. Myers et al.   Annual Review of Physiology