RNA helicase DDX3 maintains lipid homeostasis through upregulation of the microsomal triglyceride transfer protein by interacting with HNF4 and SHP

Hepatitis C virus suppresses Hepatocyte Nuclear Factor 4 alpha, a key regulator of hepatocellular carcinoma

(2016) Ioanna Vallianou et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The molecular hallmarks of epigenetic control

(2016) C. David Allis et al.   NATURE REVIEWS GENETICS

DDX3 promotes tumor invasion in colorectal cancer via the CK1ε/Dvl2 axis

(2016) Tsung-Ying He et al.   Scientific Reports

DDX3 Represses Stemness by Epigenetically Modulating Tumor-suppressive miRNAs in Hepatocellular Carcinoma

(2016) Hao-Kang Li et al.   Scientific Reports

DDX3 functions in antiviral innate immunity through translational control of PACT

(2015) Ming-Chih Lai et al.   FEBS Journal

Y-Box Binding Protein 1 Stabilizes Hepatitis C Virus NS5A via Phosphorylation-Mediated Interaction with NS5A To Regulate Viral Propagation

(2015) Wei-Ting Wang et al.   JOURNAL OF VIROLOGY

Dynamic Interaction of Stress Granules, DDX3X, and IKK-α Mediates Multiple Functions in Hepatitis C Virus Infection

(2015) Véronique Pène et al.   JOURNAL OF VIROLOGY

RNA helicase DDX3: at the crossroad of viral replication and antiviral immunity

(2015) Fernando Valiente-Echeverría et al.   REVIEWS IN MEDICAL VIROLOGY

Human DExD/H RNA helicases: Emerging roles in stress survival regulation

(2014) Jing-Wen Shih et al.   CLINICA CHIMICA ACTA

DDX3 modulates cell adhesion and motility and cancer cell metastasis via Rac1-mediated signaling pathway

(2014) H-H Chen et al.   ONCOGENE

Human PXR modulates hepatotoxicity associated with rifampicin and isoniazid co-therapy

(2013) Feng Li et al.   NATURE MEDICINE

DDX3 loss by p53 inactivation promotes tumor malignancy via the MDM2/Slug/E-cadherin pathway and poor patient outcome in non-small-cell lung cancer

(2013) D-W Wu et al.   ONCOGENE

The role of the DEAD-box RNA helicase DDX3 in mRNA metabolism

(2013) Ricardo Soto-Rifo et al.   Wiley Interdisciplinary Reviews-RNA

DEAD-box protein DDX3 associates with eIF4F to promote translation of selected mRNAs

(2012) Ricardo Soto-Rifo et al.   EMBO JOURNAL

MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis

(2012) Wei-Chih Tsai et al.   JOURNAL OF CLINICAL INVESTIGATION

Nonalcoholic fatty liver disease: Current and potential therapies

(2012) Mohamed Abdellah Ibrahim et al.   LIFE SCIENCES

Critical roles of RNA helicase DDX3 and its interactions with eIF4E/PABP1 in stress granule assembly and stress response

(2011) Jing-Wen Shih et al.   BIOCHEMICAL JOURNAL

The role of DDX3 in regulating Snail

(2011) Mianen Sun et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Regulation of microsomal triglyceride transfer protein

(2011) M Mahmood Hussain et al.   Clinical Lipidology

Positive regulation of hepatic miR-122 expression by HNF4α

(2011) Zhen-Ya Li et al.   JOURNAL OF HEPATOLOGY

A High Resolution Genome-Wide Scan of HNF4α Recognition Sites Infers a Regulatory Gene Network in Colon Cancer

(2011) Fridtjof Weltmeier et al.   PLoS One

Diurnal Regulation of MTP and Plasma Triglyceride by CLOCK Is Mediated by SHP

(2010) Xiaoyue Pan et al.   Cell Metabolism

Abnormalities of lipid metabolism in hepatitis C virus infection

(2010) F. Negro   GUT

Hepatic steatosis in hepatitis C is a storage disease due to HCV interaction with microsomal triglyceride transfer protein (MTP)

(2010) Silvia Mirandola et al.   Nutrition & Metabolism

Hepatitis C Virus Core Protein Abrogates the DDX3 Function That Enhances IPS-1-Mediated IFN–Beta Induction

(2010) Hiroyuki Oshiumi et al.   PLoS One

Microscopic dissection of the process of stress granule assembly

(2009) Ken Fujimura et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Activation of SIRT1 by Resveratrol Represses Transcription of the Gene for the Cytosolic Form of Phosphoenolpyruvate Carboxykinase (GTP) by Deacetylating Hepatic Nuclear Factor 4α

(2009) Jianqi Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Requirement of cellular DDX3 for hepatitis C virus replication is unrelated to its interaction with the viral core protein

(2009) A. G. N. Angus et al.   JOURNAL OF GENERAL VIROLOGY

Microsomal triglyceride transfer protein polymorphism (−493G/T) is associated with hepatic steatosis in patients with chronic hepatitis C

(2009) Silvia Mirandola et al.   LIVER INTERNATIONAL

Secretion of Hepatitis C Virus Envelope Glycoproteins Depends on Assembly of Apolipoprotein B Positive Lipoproteins

(2009) Vinca Icard et al.   PLoS One

Hepatitis C virus hijacks host lipid metabolism

(2009) Gulam H. Syed et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Microsomal triglyceride transfer protein (MTP) -493G/T gene polymorphism contributes to fat liver accumulation in HCV genotype 3 infected patients

(2008) R. Zampino et al.   JOURNAL OF VIRAL HEPATITIS

The DEAD-Box RNA Helicase DDX3 Associates with Export Messenger Ribonucleoproteins as well asTip-associated Protein and Participates in Translational Control

(2008) Ming-Chih Lai et al.   MOLECULAR BIOLOGY OF THE CELL

Oncogenic role of DDX3 in breast cancer biogenesis

(2008) M Botlagunta et al.   ONCOGENE