A novel microfluidic 3D platform for culturing pancreatic ductal adenocarcinoma cells: comparison with in vitro cultures and in vivo xenografts

Preclinical models of pancreatic ductal adenocarcinoma

(2015) Chang-Il Hwang et al.   JOURNAL OF PATHOLOGY

Organs-on-chips at the frontiers of drug discovery

(2015) Eric W. Esch et al.   NATURE REVIEWS DRUG DISCOVERY

Critical analysis of 3-D organoid in vitro cell culture models for high-throughput drug candidate toxicity assessments

(2014) Anna Astashkina et al.   ADVANCED DRUG DELIVERY REVIEWS

Three-Dimensional Cell Culture Systems and Their Applications in Drug Discovery and Cell-Based Biosensors

(2014) Rasheena Edmondson et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Towards plug and play filling of microfluidic devices by utilizing networks of capillary stop valves

(2014) B. Hagmeyer et al.   Biomicrofluidics

Three-dimensional cancer models mimic cell-matrix interactions in the tumour microenvironment

(2014) D. Herrmann et al.   CARCINOGENESIS

Pancreatic cancer organotypics: High throughput, preclinical models for pharmacological agent evaluation

(2014) Stacey J Coleman   WORLD JOURNAL OF GASTROENTEROLOGY

High-throughput Image Analysis of Tumor Spheroids: A User-friendly Software Application to Measure the Size of Spheroids Automatically and Accurately

(2014) Wenjin Chen et al.   Jove-Journal of Visualized Experiments

A review of microfabrication and hydrogel engineering for micro-organs on chips

(2013) Marine Verhulsel et al.   BIOMATERIALS

A bioengineered heterotypic stroma–cancer microenvironment model to study pancreatic ductal adenocarcinoma

(2013) Cole R. Drifka et al.   LAB ON A CHIP

Disease-on-a-chip: mimicry of tumor growth in mammary ducts

(2013) Pierre-Alexandre Vidi et al.   LAB ON A CHIP

Three-dimensional cell culture: the missing link in drug discovery

(2012) Susan Breslin et al.   DRUG DISCOVERY TODAY

Numerical modelling and measurement of cell trajectories in 3-D under the influence of dielectrophoretic and hydrodynamic forces

(2012) Felix Holzner et al.   ELECTROPHORESIS

A phase II trial of Erlotinib in combination with gemcitabine and cisplatin in advanced pancreatic cancer

(2012) In Gyu Hwang et al.   INVESTIGATIONAL NEW DRUGS

Patterning microscale extracellular matrices to study endothelial and cancer cell interactions in vitro

(2012) Laura E. Dickinson et al.   LAB ON A CHIP

Microengineered physiological biomimicry: Organs-on-Chips

(2012) Dongeun Huh et al.   LAB ON A CHIP

Mouse models of pancreatic cancer

(2012) Marta Herreros-Villanueva   WORLD JOURNAL OF GASTROENTEROLOGY

“Artificial micro organs”—a microfluidic device for dielectrophoretic assembly of liver sinusoids

(2011) Julia Schütte et al.   BIOMEDICAL MICRODEVICES

From 3D cell culture to organs-on-chips

(2011) Dongeun Huh et al.   TRENDS IN CELL BIOLOGY

Chemotherapy resistance in acute lymphoblastic leukemia requires hERG1 channels and is overcome by hERG1 blockers

(2010) S. Pillozzi et al.   BLOOD

Multicellular tumor spheroids: An underestimated tool is catching up again

(2010) Franziska Hirschhaeuser et al.   JOURNAL OF BIOTECHNOLOGY

A Review of Three-Dimensional In Vitro Tissue Models for Drug Discovery and Transport Studies

(2010) Nelita T. Elliott et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

A method for patterned in situ biofunctionalization in injection-molded microfluidic devices

(2010) Julia Schütte et al.   LAB ON A CHIP

Phenotype and Genotype of Pancreatic Cancer Cell Lines

(2010) Emily L. Deer et al.   PANCREAS

In vitromodels of pancreatic cancer for translational oncology research

(2009) Georg Feldmann et al.   Expert Opinion on Drug Discovery

A microfluidic 3D hepatocyte chip for drug toxicity testing

(2009) Yi-Chin Toh et al.   LAB ON A CHIP

Modulating effect of the PI3-kinase inhibitor LY294002 on cisplatin in human pancreatic cancer cells

(2008) Masao Fujiwara et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH