Biogenesis of Pro-senescent Microparticles by Endothelial Colony Forming Cells from Premature Neonates is driven by SIRT1-Dependent Epigenetic Regulation of MKK6

MicroRNA-183-5p Increases with Age in Bone-Derived Extracellular Vesicles, Suppresses Bone Marrow Stromal (Stem) Cell Proliferation, and Induces Stem Cell Senescence

(2017) Colleen Davis et al.   TISSUE ENGINEERING PART A

Endothelial Microparticles From Acute Coronary Syndrome Patients Induce Premature Coronary Artery Endothelial Cell Aging and ThrombogenicityClinical Perspective

(2016) Malak Abbas et al.   CIRCULATION

Endogenous Transmembrane TNF-Alpha Protects Against Premature Senescence in Endothelial Colony Forming CellsNovelty and Significance

(2016) Linden A. Green et al.   CIRCULATION RESEARCH

SIRT1 in Endothelial Cells as a Novel Target for the Prevention of Early Vascular Aging

(2016) Yumeng Guo et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Vascular Ageing and Exercise: Focus on Cellular Reparative Processes

(2016) Mark D. Ross et al.   Oxidative Medicine and Cellular Longevity

Microparticles as new markers of cardiovascular risk in diabetes and beyond

(2016) Francesca Santilli et al.   THROMBOSIS AND HAEMOSTASIS

Endothelial Progenitor Cells as Prognostic Markers of Preterm Birth-Associated Complications

(2016) Mariane Bertagnolli et al.   Stem Cells Translational Medicine

The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs

(2015) Yi Zhu et al.   AGING CELL

Role of p38 mitogen-activated protein kinase in vascular endothelial aging: Interaction with Arginase-II and S6K1 signaling pathway

(2015) Zongsong Wu et al.   Aging-US

Shear stress-induced mitochondrial biogenesis decreases the release of microparticles from endothelial cells

(2015) Ji-Seok Kim et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Suppression of the senescence-associated secretory phenotype (SASP) in human fibroblasts using small molecule inhibitors of p38 MAP kinase and MK2

(2015) Dauren Alimbetov et al.   BIOGERONTOLOGY

Vascular Wall Progenitor Cells in Health and Disease

(2015) P. J. Psaltis et al.   CIRCULATION RESEARCH

Fundamental properties of unperturbed haematopoiesis from stem cells in vivo

(2015) Katrin Busch et al.   NATURE

Overexpression of the microRNA miR-433 promotes resistance to paclitaxel through the induction of cellular senescence in ovarian cancer cells

(2015) Karolina Weiner-Gorzel et al.   Cancer Medicine

SIRT1-mediated epigenetic downregulation of plasminogen activator inhibitor-1 prevents vascular endothelial replicative senescence

(2014) Yan-Zhen Wan et al.   AGING CELL

Senescent cells: SASPected drivers of age-related pathologies

(2014) Yossi Ovadya et al.   BIOGERONTOLOGY

Accelerated senescence of cord blood endothelial progenitor cells in premature neonates is driven by SIRT1 decreased expression

(2014) Paula Frizera Vassallo et al.   BLOOD

Preeclampsia, prematurity and cardiovascular health in adult life

(2014) Adam J. Lewandowski et al.   EARLY HUMAN DEVELOPMENT

Quantification and Size-profiling of Extracellular Vesicles Using Tunable Resistive Pulse Sensing

(2014) Sybren L. N. Maas et al.   Jove-Journal of Visualized Experiments

Myotube-derived exosomal miRNAs downregulate Sirtuin1 in myoblasts during muscle cell differentiation

(2013) Alexis Forterre et al.   CELL CYCLE

Evolving Role of Microparticles in the Pathophysiology of Endothelial Dysfunction

(2013) F. Lovren et al.   CLINICAL CHEMISTRY

A complex secretory program orchestrated by the inflammasome controls paracrine senescence

(2013) Juan Carlos Acosta et al.   NATURE CELL BIOLOGY

Ex Vivo Expansion of Human outgrowth Endothelial Cells Leads to IL-8-Mediated Replicative Senescence and Impaired Vasoreparative Function

(2013) Reinhold J. Medina et al.   STEM CELLS

Dysfunction of Endothelial Progenitor Cells from Smokers and Chronic Obstructive Pulmonary Disease Patients Due to Increased DNA Damage and Senescence

(2013) Koralia E. Paschalaki et al.   STEM CELLS

Oncogene- and Oxidative Stress-Induced Cellular Senescence Shows Distinct Expression Patterns of Proinflammatory Cytokines in Vascular Endothelial Cells

(2013) Etsu Suzuki et al.   TheScientificWorldJOURNAL

The role of exosomes and microRNAs in senescence and aging

(2012) Dan Xu et al.   ADVANCED DRUG DELIVERY REVIEWS

High-Sensitivity Flow Cytometry Provides Access to Standardized Measurement of Small-Size Microparticles—Brief Report

(2012) Stéphane Robert et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Aging, Rejuvenation, and Epigenetic Reprogramming: Resetting the Aging Clock

(2012) Thomas A. Rando et al.   CELL

ENCODE Data in the UCSC Genome Browser: year 5 update

(2012) Kate R. Rosenbloom et al.   NUCLEIC ACIDS RESEARCH

The Gene Expression Analysis of Blood Reveals S100A11 and AQP9 as Potential Biomarkers of Infective Endocarditis

(2012) Franck Thuny et al.   PLoS One

Microparticles Induce Cell Cycle Arrest Through Redox‐Sensitive Processes in Endothelial Cells: Implications in Vascular Senescence

(2012) Dylan Burger et al.   Journal of the American Heart Association

Endothelial Microparticle Formation by Angiotensin II Is Mediated via Ang II Receptor Type I/NADPH Oxidase/ Rho Kinase Pathways Targeted to Lipid Rafts

(2011) Dylan Burger et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

A switch toward angiostatic gene expression impairs the angiogenic properties of endothelial progenitor cells in low birth weight preterm infants

(2011) I. Ligi et al.   BLOOD

Emerging role of NF-κB signaling in the induction of senescence-associated secretory phenotype (SASP)

(2011) Antero Salminen et al.   CELLULAR SIGNALLING

General and Respiratory Health Outcomes in Adult Survivors of Bronchopulmonary Dysplasia

(2011) Aisling Gough et al.   CHEST

Repression of P66Shc Expression by SIRT1 Contributes to the Prevention of Hyperglycemia-Induced Endothelial Dysfunction

(2011) Shuang Zhou et al.   CIRCULATION RESEARCH

p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype

(2011) Adam Freund et al.   EMBO JOURNAL

Sterile inflammation of endothelial cell-derived apoptotic bodies is mediated by interleukin-1 

(2011) Y. Berda-Haddad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cigarette Smoke-Related Hydroquinone Induces Filamentous Actin Reorganization and Heat Shock Protein 27 Phosphorylation through p38 and Extracellular Signal-Regulated Kinase 1/2 in Retinal Pigment Epithelium

(2010) Marianne Pons et al.   AMERICAN JOURNAL OF PATHOLOGY

The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression

(2010) Jean-Philippe Coppé et al.   Annual Review of Pathology-Mechanisms of Disease

The Many Faces of Endothelial Microparticles

(2010) Françoise Dignat-George et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Microparticles

(2010) Sebastian F. Mause et al.   CIRCULATION RESEARCH

Standardization of platelet-derived microparticle enumeration by flow cytometry with calibrated beads: results of the International Society on Thrombosis and Haemostasis SSC Collaborative workshop

(2010) R. LACROIX et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Low Birth Weight Infants and the Developmental Programming of Hypertension: A Focus on Vascular Factors

(2010) Isabelle Ligi et al.   SEMINARS IN PERINATOLOGY

The role of epigenetics in aging and age-related diseases

(2009) Vincenzo Calvanese et al.   AGEING RESEARCH REVIEWS

Senescence, apoptosis, and stem cell biology: the rationale for an expanded view of intracrine action

(2009) Richard N. Re et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Hyperoxia disrupts vascular endothelial growth factor-nitric oxide signaling and decreases growth of endothelial colony-forming cells from preterm infants

(2009) Hideshi Fujinaga et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

TRAIL/Apo2L Mediates the Release of Procoagulant Endothelial Microparticles Induced by Thrombin In Vitro

(2009) Stéphanie Simoncini et al.   CIRCULATION RESEARCH

Stress-induced premature senescence of endothelial cells: a perilous state between recovery and point of no return

(2009) Michael S Goligorsky et al.   CURRENT OPINION IN HEMATOLOGY

p38 mitogen-activated protein kinase targets the production of proinflammatory endothelial microparticles

(2009) A. M. CURTIS et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion

(2009) Francis Rodier et al.   NATURE CELL BIOLOGY

Impaired DNA Damage Response, Genome Instability, and Tumorigenesis in SIRT1 Mutant Mice

(2008) Rui-Hong Wang et al.   CANCER CELL

SIRT1 Redistribution on Chromatin Promotes Genomic Stability but Alters Gene Expression during Aging

(2008) Philipp Oberdoerffer et al.   CELL