TGFβ signaling is associated with changes in inflammatory gene expression and perineuronal net degradation around inhibitory neurons following various neurological insults

Casting a Wide Net: Role of Perineuronal Nets in Neural Plasticity

(2016) Barbara A. Sorg et al.   JOURNAL OF NEUROSCIENCE

A potential role for glia-derived extracellular matrix remodeling in postinjury epilepsy

(2016) Soo Young Kim et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Synaptic plasticity in area CA1 of rat hippocampal slices following intraventricular application of albumin

(2016) Seda Salar et al.   NEUROBIOLOGY OF DISEASE

Losartan Attenuates Myocardial Endothelial-To-Mesenchymal Transition in Spontaneous Hypertensive Rats via Inhibiting TGF-β/Smad Signaling

(2016) Miao Wu et al.   PLoS One

ALIAS (Albumin in Acute Ischemic Stroke) Trials

(2016) Renee’ H. Martin et al.   STROKE

Perineuronal net degradation in epilepsy

(2015) Elyse K. Rankin-Gee et al.   EPILEPSIA

Involvement of chondroitin 6-sulfation in temporal lobe epilepsy

(2015) Noriko Yutsudo et al.   EXPERIMENTAL NEUROLOGY

TGFβ1 exacerbates blood–brain barrier permeability in a mouse model of hepatic encephalopathy via upregulation of MMP9 and downregulation of claudin-5

(2015) Matthew A McMillin et al.   LABORATORY INVESTIGATION

Albumin induces excitatory synaptogenesis through astrocytic TGF-β/ALK5 signaling in a model of acquired epilepsy following blood–brain barrier dysfunction

(2015) Itai Weissberg et al.   NEUROBIOLOGY OF DISEASE

Blood-Brain Barrier Breakdown in the Aging Human Hippocampus

(2015) Axel Montagne et al.   NEURON

Mitochondrial Protection by Exogenous Otx2 in Mouse Retinal Neurons

(2015) Hyoung-Tai Kim et al.   Cell Reports

Losartan prevents acquired epilepsy via TGF-β signaling suppression

(2014) Guy Bar-Klein et al.   ANNALS OF NEUROLOGY

Role of TGF-β signaling pathway on Tenascin C protein upregulation in a pilocarpine seizure model

(2014) Octavio Mercado-Gómez et al.   EPILEPSY RESEARCH

Extracellular matrix regulation of inflammation in the healthy and injured spinal cord

(2014) Andrew D. Gaudet et al.   EXPERIMENTAL NEUROLOGY

Astrocytic transforming growth factor-beta signaling reduces subacute neuroinflammation after stroke in mice

(2014) Egle Cekanaviciute et al.   GLIA

Metalloproteinase inhibition prevents inhibitory synapse reorganization and seizure genesis

(2014) Emily Pollock et al.   NEUROBIOLOGY OF DISEASE

Iron and neurodegeneration in the multiple sclerosis brain

(2013) Simon Hametner et al.   ANNALS OF NEUROLOGY

Primary Hippocampal Neurons, Which Lack Four Crucial Extracellular Matrix Molecules, Display Abnormalities of Synaptic Structure and Function and Severe Deficits in Perineuronal Net Formation

(2013) M. Geissler et al.   JOURNAL OF NEUROSCIENCE

NF-κB-Induced IL-6 Ensures STAT3 Activation and Tumor Aggressiveness in Glioblastoma

(2013) Braden C. McFarland et al.   PLoS One

Perineuronal nets protect fast-spiking interneurons against oxidative stress

(2013) J.-H. Cabungcal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Macrophages prevent hemorrhagic infarct transformation in murine stroke models

(2012) Michael Gliem et al.   ANNALS OF NEUROLOGY

Seizure-induced brain-borne inflammation sustains seizure recurrence and blood-brain barrier damage

(2012) Laura Librizzi et al.   ANNALS OF NEUROLOGY

Inhibitory Interneuron Deficit Links Altered Network Activity and Cognitive Dysfunction in Alzheimer Model

(2012) Laure Verret et al.   CELL

Modulation of Transforming Growth Factor-  Signaling and Extracellular Matrix Production in Myxomatous Mitral Valves by Angiotensin II Receptor Blockers

(2012) A. Geirsson et al.   CIRCULATION

Cliniconeuropathologic correlations show astroglial albumin storage as a common factor in epileptogenic vascular lesions

(2012) Anna Raabe et al.   EPILEPSIA

Blood-brain barrier dysfunction-induced inflammatory signaling in brain pathology and epileptogenesis

(2012) Soo Young Kim et al.   EPILEPSIA

Otx2 Binding to Perineuronal Nets Persistently Regulates Plasticity in the Mature Visual Cortex

(2012) M. Beurdeley et al.   JOURNAL OF NEUROSCIENCE

Fast spiking interneuron control of seizure propagation in a cortical slice model of focal epilepsy

(2012) Mario Cammarota et al.   JOURNAL OF PHYSIOLOGY-LONDON

Targeting the TGFβ signalling pathway in disease

(2012) Rosemary J. Akhurst et al.   NATURE REVIEWS DRUG DISCOVERY

Functional alterations in GABAergic fast-spiking interneurons in chronically injured epileptogenic neocortex

(2012) Yunyong Ma et al.   NEUROBIOLOGY OF DISEASE

Peri-infarct blood–brain barrier dysfunction facilitates induction of spreading depolarization associated with epileptiform discharges

(2012) E.G. Lapilover et al.   NEUROBIOLOGY OF DISEASE

Neurological complications of acute ischaemic stroke

(2011) Joyce S Balami et al.   LANCET NEUROLOGY

Gamma oscillations in the hippocampus require high complex I gene expression and strong functional performance of mitochondria

(2010) Oliver Kann et al.   BRAIN

Impaired striatal GABA transmission in experimental autoimmune encephalomyelitis

(2010) Silvia Rossi et al.   BRAIN BEHAVIOR AND IMMUNITY

Reorganization of Inhibitory Synaptic Circuits in Rodent Chronically Injured Epileptogenic Neocortex

(2010) X. Jin et al.   CEREBRAL CORTEX

Fibrinogen Triggers Astrocyte Scar Formation by Promoting the Availability of Active TGF-  after Vascular Damage

(2010) C. Schachtrup et al.   JOURNAL OF NEUROSCIENCE

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

Blood–brain barrier breakdown as a therapeutic target in traumatic brain injury

(2010) Dan Shlosberg et al.   Nature Reviews Neurology

Epileptogenic temporal cavernous malformations: Operative strategies and postoperative seizure outcomes

(2010) Kristen Upchurch et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Compartmentalization from the outside: the extracellular matrix and functional microdomains in the brain

(2010) Alexander Dityatev et al.   TRENDS IN NEUROSCIENCES

Transcriptome Profiling Reveals TGF-  Signaling Involvement in Epileptogenesis

(2009) L. P. Cacheaux et al.   JOURNAL OF NEUROSCIENCE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Experience-Dependent Transfer of Otx2 Homeoprotein into the Visual Cortex Activates Postnatal Plasticity

(2008) Sayaka Sugiyama et al.   CELL

Important role of matrix metalloproteinase 9 in epileptogenesis

(2008) Grzegorz M. Wilczynski et al.   JOURNAL OF CELL BIOLOGY

The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders

(2008) Berislav V. Zlokovic   NEURON