Chitosan promotes ROS-mediated apoptosis and S phase cell cycle arrest in triple-negative breast cancer cells: evidence for intercalative interaction with genomic DNA

Flavonoids of Rosa roxburghii Tratt exhibit radioprotection and anti-apoptosis properties via the Bcl-2(Ca2+)/Caspase-3/PARP-1 pathway

(2016) Ping Xu et al.   APOPTOSIS

Microscopic and spectroscopic analysis of chitosan–DNA conjugates

(2016) D. Agudelo et al.   CARBOHYDRATE POLYMERS

Synthesis, characterization and biological evaluation of labile intercalative ruthenium(ii) complexes for anticancer drug screening

(2016) Huaiyi Huang et al.   DALTON TRANSACTIONS

DNA/chitosan electrostatic complex

(2016) Lourdes Mónica Bravo-Anaya et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Photodynamic killing of cancer cells by a Platinum(II) complex with cyclometallating ligand

(2016) Rachel E. Doherty et al.   Scientific Reports

A novel polysaccharide from Sargassum integerrimum induces apoptosis in A549 cells and prevents angiogensis in vitro and in vivo

(2016) Ge Liu et al.   Scientific Reports

Synergistic chemopreventive effects of curcumin and berberine on human breast cancer cells through induction of apoptosis and autophagic cell death

(2016) Kai Wang et al.   Scientific Reports

TAK1 inhibitor NG25 enhances doxorubicin-mediated apoptosis in breast cancer cells

(2016) Zhenyu Wang et al.   Scientific Reports

Spiro[pyrrolidine-3, 3´-oxindole] as potent anti-breast cancer compounds: Their design, synthesis, biological evaluation and cellular target identification

(2016) Santanu Hati et al.   Scientific Reports

A ruthenium polypyridyl intercalator stalls DNA replication forks, radiosensitizes human cancer cells and is enhanced by Chk1 inhibition

(2016) Martin R. Gill et al.   Scientific Reports

Synthesis and mechanisms of action of novel harmine derivatives as potential antitumor agents

(2016) Xiao-Fei Zhang et al.   Scientific Reports

Fructose induces mitochondrial dysfunction and triggers apoptosis in skeletal muscle cells by provoking oxidative stress

(2015) Natasha Jaiswal et al.   APOPTOSIS

Tunicamycin promotes apoptosis in leukemia cells through ROS generation and downregulation of survivin expression

(2015) Eun Jin Lim et al.   APOPTOSIS

Apoptosis induction in human breast cancer (MCF-7) cells by a novel venom l-amino acid oxidase (Rusvinoxidase) is independent of its enzymatic activity and is accompanied by caspase-7 activation and reactive oxygen species production

(2015) Ashis K. Mukherjee et al.   APOPTOSIS

SZC017, a novel oleanolic acid derivative, induces apoptosis and autophagy in human breast cancer cells

(2015) Lei Gao et al.   APOPTOSIS

Characterization and In Vitro Evaluation of Cytotoxicity, Antimicrobial and Antioxidant Activities of Chitosans Extracted from Three Different Marine Sources

(2015) Sawssen Hajji et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Anticancer properties of chitosan on human melanoma are cell line dependent

(2015) Laure Gibot et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Groove binding interaction between daphnetin and calf thymus DNA

(2015) Xiaoyue Zhou et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Stability of Chitosan—A Challenge for Pharmaceutical and Biomedical Applications

(2015) Emilia Szymańska et al.   Marine Drugs

Investigation of the binding modes between AIE-active molecules and dsDNA by single molecule force spectroscopy

(2015) Ying Chen et al.   Nanoscale

Spectroscopic and molecular docking evidence of aspirin and diflunisal binding to DNA: a comparative study

(2015) Mohammed Amir Husain et al.   RSC Advances

Single molecular analysis of the interaction between DNA and chitosan

(2015) Yanwei Wang et al.   RSC Advances

Physicochemical and biological characterization of chitosan-microRNA nanocomplexes for gene delivery to MCF-7 breast cancer cells

(2015) B. Santos-Carballal et al.   Scientific Reports

Chitosan nanoparticles: A positive modulator of innate immune responses in plants

(2015) Swarnendu Chandra et al.   Scientific Reports

Arbutin, an intracellular hydroxyl radical scavenger, protects radiation-induced apoptosis in human lymphoma U937 cells

(2014) Li-Hua Wu et al.   APOPTOSIS

Chitin and chitosan in selected biomedical applications

(2014) A. Anitha et al.   PROGRESS IN POLYMER SCIENCE

Quercetin induces cytochrome-c release and ROS accumulation to promote apoptosis and arrest the cell cycle in G2/M, in cervical carcinoma: signal cascade and drug-DNA interaction

(2013) K. Bishayee et al.   CELL PROLIFERATION

Interaction of anticancer drug mitoxantrone with DNA hexamer sequence d-(CTCGAG)2 by absorption, fluorescence and circular dichroism spectroscopy

(2013) Shilpa Dogra et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Drug–DNA interactions and their study by UV–Visible, fluorescence spectroscopies and cyclic voltametry

(2013) Muhammad Sirajuddin et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Evaluation of DNA-binding, radical scavenging and cytotoxic activity of five coordinated Cd(ii) complexes containing 2-acetylpyridine-N4-substituted thiosemicarbazone

(2013) Rajendran Manikandan et al.   RSC Advances

Anticancer polysaccharides from natural resources: A review of recent research

(2012) Aizhen Zong et al.   CARBOHYDRATE POLYMERS

Spectroscopic studies of the effects of anticancer drug mitoxantrone interaction with calf-thymus DNA

(2012) Shweta Agarwal et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

DNA interaction studies of a platinum (II) complex containing an antiviral drug, ribavirin: The effect of metal on DNA binding

(2012) Nahid Shahabadi et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

Synthesis, characterization and DNA binding properties of rutin–iron complex

(2012) Stalin Selvaraj et al.   RSC Advances

Chitosan—A versatile semi-synthetic polymer in biomedical applications

(2011) M. Dash et al.   PROGRESS IN POLYMER SCIENCE

Detailed spectroscopic investigations to reveal the nature of interaction of anionic porphyrin with calf thymus DNA

(2010) Sudeshna Bhattacharya et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Studies on the interaction of copper complexes of (−)-epicatechin gallate and (−)-epigallocatechin gallate with calf thymus DNA

(2008) Kalyan Sundar Ghosh et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Studies on the interaction of isoxazolcurcumin with calf thymus DNA

(2007) Rabindranath Bera et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES