Free-radical initiated cascade methylation or trideuteromethylation of isocyanides with dimethyl sulfoxides

Visible-light-induced and iron-catalyzed methylation of N-arylacrylamides with dimethyl sulphoxide: a convenient access to 3-ethyl-3-methyl oxindoles

(2017) Zuguang Xie et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

The Applications of Dimethyl Sulfoxide as Reagent in Organic Synthesis

(2016) Xiao-Feng Wu et al.   ADVANCED SYNTHESIS & CATALYSIS

Radical trideuteromethylation with deuterated dimethyl sulfoxide in the synthesis of heterocycles and labelled building blocks

(2016) Roberta Caporaso et al.   CHEMICAL COMMUNICATIONS

Recent progress in imidoyl radical-involved reactions

(2016) Jian Lei et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Dimethyl Sulfoxide as a Synthon in Organic Chemistry

(2016) Jakob Magolan et al.   SYNTHESIS-STUTTGART

Cu-Catalyzed selective C3-formylation of imidazo[1,2-a]pyridine C–H bonds with DMSO using molecular oxygen

(2015) Hua Cao et al.   CHEMICAL COMMUNICATIONS

Recent advances in the synthesis of nitrogen heterocycles via radical cascade reactions using isonitriles as radical acceptors

(2015) Bo Zhang et al.   CHEMICAL SOCIETY REVIEWS

Di-tertButyl Peroxide-Promoted Sequential Methylation and Intramolecular Aromatization of Isonitriles

(2014) Qiang Dai et al.   ADVANCED SYNTHESIS & CATALYSIS

Synthesis of 6-acyl phenanthridines by oxidative radical decarboxylation–cyclization of α-oxocarboxylates and isocyanides

(2014) Jie Liu et al.   CHEMICAL COMMUNICATIONS

tert-Butyl peroxybenzoate (TBPB)-mediated 2-isocyanobiaryl insertion with 1,4-dioxane: efficient synthesis of 6-alkyl phenanthridines via C(sp3)–H/C(sp2)–H bond functionalization

(2014) Jia-Jia Cao et al.   CHEMICAL COMMUNICATIONS

The benzoyl peroxide-promoted functionalization of simple alkanes with 2-aryl phenyl isonitrile

(2014) Wanxing Sha et al.   CHEMICAL COMMUNICATIONS

Synthesis of isoquinolines via visible light-promoted insertion of vinyl isocyanides with diaryliodonium salts

(2014) Heng Jiang et al.   CHEMICAL COMMUNICATIONS

Transition-metal-free, visible-light induced cyclization of arylsulfonyl chlorides with 2-isocyanobiphenyls to produce phenanthridines

(2014) Lijun Gu et al.   CHEMICAL COMMUNICATIONS

Synthesis of 6-substituted phenanthridines by metal-free, visible-light induced aerobic oxidative cyclization of 2-isocyanobiphenyls with hydrazines

(2014) Tiebo Xiao et al.   GREEN CHEMISTRY

FeCl3-Promoted Carboxamidation and Cyclization of Aryl Isonitriles with Formamides toward Phenanthridine-6-carboxamides

(2014) Hai-Yong Tu et al.   JOURNAL OF ORGANIC CHEMISTRY

C–H Methylation of Heteroarenes Inspired by Radical SAM Methyl Transferase

(2014) Jinghan Gui et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Arylative Cyclization of 2-Isocyanobiphenyls with Anilines: One-Pot Synthesis of 6-Arylphenanthridines via Competitive Reaction Pathways

(2014) Zhonghua Xia et al.   ORGANIC LETTERS

A Free-Radical Cascade Trifluoromethylation/Cyclization of N-Arylmethacrylamides and Enynes with Sodium Trifluoromethanesulfinate and Iodine Pentoxide

(2014) Lizhi Zhang et al.   ORGANIC LETTERS

Co(acac)2/O2-Mediated Oxidative Isocyanide Insertion with 2-Aryl Anilines: Efficient Synthesis of 6-Amino Phenanthridine Derivatives

(2014) Tong-Hao Zhu et al.   ORGANIC LETTERS

The Benzoyl Peroxide Promoted Dual C–C Bond Formation via Dual C–H Bond Cleavage: α-Phenanthridinylation of Ether by Isocyanide

(2014) Lei Wang et al.   ORGANIC LETTERS

A Free-Radical Cascade Methylation/Cyclization of N-Arylacrylamides and Isocyanides with Dicumyl Peroxide

(2014) Zhengbao Xu et al.   ORGANIC LETTERS

A Free Radical Cascade Cyclization of Isocyanides with Simple Alkanes and Alcohols

(2014) Zejiang Li et al.   ORGANIC LETTERS

Profound Methyl Effects in Drug Discovery and a Call for New CH Methylation Reactions

(2013) Heike Schönherr et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium(I)-Catalyzed Redox-Economic Cross-Coupling of Carboxylic Acids with Arenes Directed by N-Containing Groups

(2013) Fei Pan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of 6-Alkylated Phenanthridine Derivatives Using Photoredox Neutral Somophilic Isocyanide Insertion

(2013) Heng Jiang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

6-Trifluoromethyl-Phenanthridines through Radical Trifluoromethylation of Isonitriles

(2013) Bo Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent advances in isocyanide insertion chemistry

(2013) Guanyinsheng Qiu et al.   CHEMICAL SOCIETY REVIEWS

A General Method for N-Methylation of Amines and Nitro Compounds with Dimethylsulfoxide

(2013) Xue Jiang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Using Deuterium in Drug Discovery: Leaving the Label in the Drug

(2013) Thomas G. Gant   JOURNAL OF MEDICINAL CHEMISTRY

Primary Amines as Directing Groups in the Ru-Catalyzed Synthesis of Isoquinolines, Benzoisoquinolines, and Thienopyridines

(2013) Pedro Villuendas et al.   JOURNAL OF ORGANIC CHEMISTRY

PhI(OAc)2-Mediated Synthesis of 6-(Trifluoromethyl)phenanthridines by Oxidative Cyclization of 2-Isocyanobiphenyls with CF3SiMe3 under Metal-Free Conditions

(2013) Qile Wang et al.   ORGANIC LETTERS

6-Phosphorylated Phenanthridines from 2-Isocyanobiphenyls via Radical C–P and C–C Bond Formation

(2013) Bo Zhang et al.   ORGANIC LETTERS

Isocyanide Insertion: De Novo Synthesis of Trifluoromethylated Phenanthridine Derivatives

(2013) Yuanzheng Cheng et al.   ORGANIC LETTERS

6-Aroylated Phenanthridines via Base Promoted Homolytic Aromatic Substitution (BHAS)

(2013) Dirk Leifert et al.   ORGANIC LETTERS

Free-Radical Cascade Alkylarylation of Alkenes with Simple Alkanes: Highly Efficient Access to Oxindoles via Selective (sp3)C–H and (sp2)C–H Bond Functionalization

(2013) Zejiang Li et al.   ORGANIC LETTERS

Mild Palladium-Catalyzed C–H Alkylation Using Potassium Alkyltrifluoroborates in Combination with MnF3

(2013) Sharon R. Neufeldt et al.   ORGANIC LETTERS

Palladium-Catalyzed CH Oxidation of Isoquinoline N-Oxides: Selective Alkylation with Dialkyl Sulfoxides and Halogenation with Dihalo sulfoxides

(2012) Bo Yao et al.   ADVANCED SYNTHESIS & CATALYSIS

Ruthenium-Catalyzed Highly Regioselective Cyclization of Ketoximes with Alkynes by C–H Bond Activation: A Practical Route to Synthesize Substituted Isoquinolines

(2012) Ravi Kiran Chinnagolla et al.   ORGANIC LETTERS

Weak Coordination as a Powerful Means for Developing Broadly Useful C–H Functionalization Reactions

(2011) Keary M. Engle et al.   ACCOUNTS OF CHEMICAL RESEARCH

Synthesis of Isoquinolines from α-Aryl Vinyl Azides and Internal Alkynes by Rh-Cu Bimetallic Cooperation

(2011) Yi-Feng Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

One-Pot Synthesis of Isoquinolinium Salts by Rhodium-Catalyzed CH Bond Activation: Application to the Total Synthesis of Oxychelerythrine

(2011) Jayachandran Jayakumar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Methylation Effect in Medicinal Chemistry

(2011) Eliezer J. Barreiro et al.   CHEMICAL REVIEWS

Palladium-Catalyzed Coupling of Arene C–H Bonds with Methyl- and Arylboron Reagents Assisted by the Removable 2-Pyridylsulfinyl Group

(2011) José A. Romero-Revilla et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Azaheterocycles from Aryl KetoneO-Acetyl Oximes and Internal Alkynes by Cu–Rh Bimetallic Relay Catalysts

(2011) Pei Chui Too et al.   JOURNAL OF ORGANIC CHEMISTRY

Divergent C–H Functionalizations Directed by Sulfonamide Pharmacophores: Late-Stage Diversification as a Tool for Drug Discovery

(2011) Hui-Xiong Dai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cobalt-Catalyzed Coupling of Alkyl Grignard Reagent with Benzamide and 2-Phenylpyridine Derivatives through Directed C–H Bond Activation under Air

(2011) Quan Chen et al.   ORGANIC LETTERS

Palladium-Catalyzed Alkylation ofortho-C(sp2)–H Bonds of Benzylamide Substrates with Alkyl Halides

(2011) Yingsheng Zhao et al.   ORGANIC LETTERS

Rhodium(III)-Catalyzed Synthesis of Isoquinolines from Aryl KetoneO-Acyloxime Derivatives and Internal Alkynes

(2010) Pei Chui Too et al.   ORGANIC LETTERS

DNA methylation by dimethyl sulfoxide and methionine sulfoxide triggered by hydroxyl radical and implications for epigenetic modifications

(2009) Kazuaki Kawai et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthetic Studies onN-Alkoxyamines: A Mild and Broadly Applicable Route Starting from Nitroxide Radicals and Aldehydes

(2009) Kai-Uwe Schoening et al.   JOURNAL OF ORGANIC CHEMISTRY

Isoquinoline Synthesis via Rhodium-Catalyzed Oxidative Cross-Coupling/Cyclization of Aryl Aldimines and Alkynes

(2009) Nicolas Guimond et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of 19-trideuteratedent-testosterone and the GABAAreceptor potentiatorsent-androsterone andent-etiocholanolone

(2008) Shirisha Komarapuri et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Phenanthridine synthesis via [2+2+2] cyclotrimerization reactions

(2007) Lakshminath Sripada et al.   ORGANIC & BIOMOLECULAR CHEMISTRY