Recent advances in the synthesis of nitrogen heterocycles via radical cascade reactions using isonitriles as radical acceptors

Regiospecific Synthesis of 1-Trifluoromethylisoquinolines Enabled by Photoredox Somophilic Vinyl Isocyanide Insertion

(2014) Yuanzheng Cheng et al.   ADVANCED SYNTHESIS & CATALYSIS

Catalytic Isonitrile Insertions and Condensations Initiated by RNC-X Complexation

(2014) Suravi Chakrabarty et al.   ADVANCED SYNTHESIS & CATALYSIS

Tetrabutylammonium Iodide-Catalyzed Radical Alkoxycarbonylation of 2-Isocyanobiphenyls with Carbazates: Synthesis of Phenanthridine-6-carboxylates

(2014) Xiaoqing Li et al.   ADVANCED SYNTHESIS & CATALYSIS

Synthesis of Highly Functionalized Polycyclic Quinoxaline Derivatives Using Visible-Light Photoredox Catalysis

(2014) Zhi He et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mn(ii)/O2-promoted oxidative annulation of vinyl isocyanides with boronic acids: synthesis of multi-substituted isoquinolines

(2014) Hao Wang et al.   CHEMICAL COMMUNICATIONS

Synthesis of 6-acyl phenanthridines by oxidative radical decarboxylation–cyclization of α-oxocarboxylates and isocyanides

(2014) Jie Liu et al.   CHEMICAL COMMUNICATIONS

tert-Butyl peroxybenzoate (TBPB)-mediated 2-isocyanobiaryl insertion with 1,4-dioxane: efficient synthesis of 6-alkyl phenanthridines via C(sp3)–H/C(sp2)–H bond functionalization

(2014) Jia-Jia Cao et al.   CHEMICAL COMMUNICATIONS

The benzoyl peroxide-promoted functionalization of simple alkanes with 2-aryl phenyl isonitrile

(2014) Wanxing Sha et al.   CHEMICAL COMMUNICATIONS

Mn(iii)-mediated reactions of 2-isocyanobiaryl with 1,3-dicarbonyl compounds: efficient synthesis of 6-alkylated and 6-monofluoro-alkylated phenanthridines

(2014) Jia-Jia Cao et al.   CHEMICAL COMMUNICATIONS

Synthesis of isoquinolines via visible light-promoted insertion of vinyl isocyanides with diaryliodonium salts

(2014) Heng Jiang et al.   CHEMICAL COMMUNICATIONS

TBHP-promoted sequential radical silylation and aromatisation of aryl isonitriles with silanes

(2014) Lei Wang et al.   CHEMICAL COMMUNICATIONS

Transition-metal-free, visible-light induced cyclization of arylsulfonyl chlorides with 2-isocyanobiphenyls to produce phenanthridines

(2014) Lijun Gu et al.   CHEMICAL COMMUNICATIONS

Metal-Free Multicomponent Syntheses of Pyridines

(2014) Christophe Allais et al.   CHEMICAL REVIEWS

Synthesis of 6-substituted phenanthridines by metal-free, visible-light induced aerobic oxidative cyclization of 2-isocyanobiphenyls with hydrazines

(2014) Tiebo Xiao et al.   GREEN CHEMISTRY

Radical Arylalkoxycarbonylation of 2-Isocyanobiphenyl with Carbazates: Dual C–C Bond Formation toward Phenanthridine-6-carboxylates

(2014) Changduo Pan et al.   JOURNAL OF ORGANIC CHEMISTRY

FeCl3-Promoted Carboxamidation and Cyclization of Aryl Isonitriles with Formamides toward Phenanthridine-6-carboxamides

(2014) Hai-Yong Tu et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Saturated N-Heterocycles

(2014) Cam-Van T. Vo et al.   JOURNAL OF ORGANIC CHEMISTRY

The electron is a catalyst

(2014) Armido Studer et al.   Nature Chemistry

1-Trifluoromethylated isoquinolines via radical trifluoromethylation of isonitriles

(2014) Bo Zhang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A cascade alkylarylation reaction of 2-isocyanobiphenyls with simple alkanes for 6-alkyl phenanthridines via dual C(sp3)–H/C(sp2)–H functionalizations

(2014) Zhi-Qiang Zhu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

TBHP-promoted sequential carboxamidation and aromatisation of aryl isonitriles with formamides

(2014) Xiaomei Feng et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

2-Trifluoromethylated Indoles via Radical Trifluoromethylation of Isonitriles

(2014) Bo Zhang et al.   ORGANIC LETTERS

Arylative Cyclization of 2-Isocyanobiphenyls with Anilines: One-Pot Synthesis of 6-Arylphenanthridines via Competitive Reaction Pathways

(2014) Zhonghua Xia et al.   ORGANIC LETTERS

Visible-Light-Mediated Fluoroalkylation of Isocyanides with Ethyl Bromofluoroacetates: Unified Synthesis of Mono- and Difluoromethylated Phenanthridine Derivatives

(2014) Xiaoyang Sun et al.   ORGANIC LETTERS

The Benzoyl Peroxide Promoted Dual C–C Bond Formation via Dual C–H Bond Cleavage: α-Phenanthridinylation of Ether by Isocyanide

(2014) Lei Wang et al.   ORGANIC LETTERS

A Free-Radical Cascade Methylation/Cyclization of N-Arylacrylamides and Isocyanides with Dicumyl Peroxide

(2014) Zhengbao Xu et al.   ORGANIC LETTERS

6-Perfluoroalkylated Phenanthridines via Radical Perfluoroalkylation of Isonitriles

(2014) Bo Zhang et al.   ORGANIC LETTERS

A Free Radical Cascade Cyclization of Isocyanides with Simple Alkanes and Alcohols

(2014) Zejiang Li et al.   ORGANIC LETTERS

Synthesis of phenanthridin-6-yldiphenylphosphine oxides by oxidative cyclization of 2-isocyanobiphenyls with diarylphosphine oxides

(2014) Yuewen Li et al.   TETRAHEDRON

Synthesis of 6-Phenanthridinephosphonates via a Radical Phosphonation and Cyclization Process Mediated by Manganese(III) Acetate

(2014) Yuzhen Gao et al.   Asian Journal of Organic Chemistry

Synthesis of Fused Quinoline and Quinoxaline Derivatives Enabled by Domino Radical Triple Bond Insertions

(2014) Xiaoyang Sun et al.   Asian Journal of Organic Chemistry

Synthesis of 6-Alkylated Phenanthridine Derivatives Using Photoredox Neutral Somophilic Isocyanide Insertion

(2013) Heng Jiang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

6-Trifluoromethyl-Phenanthridines through Radical Trifluoromethylation of Isonitriles

(2013) Bo Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Introduction of Fluorine and Fluorine-Containing Functional Groups

(2013) Theresa Liang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent advances in isocyanide insertion chemistry

(2013) Guanyinsheng Qiu et al.   CHEMICAL SOCIETY REVIEWS

Unravelling the labyrinth of palladium-catalysed reactions involving isocyanides

(2013) Stuart Lang   CHEMICAL SOCIETY REVIEWS

Synthesis of heterocycles via transition-metal-catalyzed hydroarylation of alkynes

(2013) Yoshihiko Yamamoto   CHEMICAL SOCIETY REVIEWS

PhI(OAc)2-Mediated Synthesis of 6-(Trifluoromethyl)phenanthridines by Oxidative Cyclization of 2-Isocyanobiphenyls with CF3SiMe3 under Metal-Free Conditions

(2013) Qile Wang et al.   ORGANIC LETTERS

6-Phosphorylated Phenanthridines from 2-Isocyanobiphenyls via Radical C–P and C–C Bond Formation

(2013) Bo Zhang et al.   ORGANIC LETTERS

Isocyanide Insertion: De Novo Synthesis of Trifluoromethylated Phenanthridine Derivatives

(2013) Yuanzheng Cheng et al.   ORGANIC LETTERS

6-Aroylated Phenanthridines via Base Promoted Homolytic Aromatic Substitution (BHAS)

(2013) Dirk Leifert et al.   ORGANIC LETTERS

Modular Synthesis of Phenanthridine Derivatives by Oxidative Cyclization of 2-Isocyanobiphenyls with Organoboron Reagents

(2012) Mamoru Tobisu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A “Renaissance” in Radical Trifluoromethylation

(2012) Armido Studer   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Radical Cascades Initiated by Intermolecular Radical Addition to Alkynes and Related Triple Bond Systems

(2012) Uta Wille   CHEMICAL REVIEWS

Anticancer Drug Design Using Scaffolds of β-Lactams, Sulfonamides, Quinoline, Quinoxaline and Natural Products. Drugs Advances in Clinical Trials

(2012) I. Balderas-Renteria et al.   CURRENT MEDICINAL CHEMISTRY

Borylation and Silylation of C–H Bonds: A Platform for Diverse C–H Bond Functionalizations

(2011) John F. Hartwig   ACCOUNTS OF CHEMICAL RESEARCH

Organocatalysis and CH Activation Meet Radical- and Electron-Transfer Reactions

(2011) Armido Studer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Direct Sp3α-C–H activation and functionalization of alcohol and ether

(2011) Shu-Yu Zhang et al.   CHEMICAL SOCIETY REVIEWS

Metal-catalysed approaches to amide bond formation

(2011) C. Liana Allen et al.   CHEMICAL SOCIETY REVIEWS

Photoinduced Intramolecular Cyclization ofo-Ethenylaryl Isocyanides with Organic Disulfides Mediated by Diphenyl Ditelluride

(2011) Takenori Mitamura et al.   JOURNAL OF ORGANIC CHEMISTRY

Iron-Catalyzed Carbonylation-Peroxidation of Alkenes with Aldehydes and Hydroperoxides

(2011) Weiping Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Isocyanides in the Synthesis of Nitrogen Heterocycles

(2010) Alexander V. Lygin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Radical Addition of Arylboronic Acids to Various Olefins under Oxidative Conditions

(2010) Arne Dickschat et al.   ORGANIC LETTERS

Solvent-Free Heterocyclic Synthesis

(2009) Marcos A. P. Martins et al.   CHEMICAL REVIEWS

(PhTe)2-Mediated Intramolecular Radical Cyclization ofo-Ethynylaryl Isocyanides Leading to Bistellurated Quinolines upon Visible-Light Irradiation

(2009) Takenori Mitamura et al.   ORGANIC LETTERS

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS

Phenanthridine synthesis via [2+2+2] cyclotrimerization reactions

(2007) Lakshminath Sripada et al.   ORGANIC & BIOMOLECULAR CHEMISTRY