Water soluble Ru(ii)–arene complexes of the antidiabetic drug metformin: DNA and protein binding, molecular docking, cytotoxicity and apoptosis-inducing activity
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Title
Water soluble Ru(ii)–arene complexes of the antidiabetic drug metformin: DNA and protein binding, molecular docking, cytotoxicity and apoptosis-inducing activity
Authors
Keywords
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Journal
RSC Advances
Volume 7, Issue 60, Pages 37706-37719
Publisher
Royal Society of Chemistry (RSC)
Online
2017-07-31
DOI
10.1039/c7ra06514k
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- (2017) Rangasamy Loganathan et al. JOURNAL OF INORGANIC BIOCHEMISTRY
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- (2016) Rakesh Kumar Gupta et al. DALTON TRANSACTIONS
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- (2016) Stefan Richter et al. DALTON TRANSACTIONS
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- (2016) Stephanie. W. Chang et al. INORGANIC CHEMISTRY
- Nonsteroidal Anti-inflammatory—Organometallic Anticancer Compounds
- (2016) Emilia Păunescu et al. INORGANIC CHEMISTRY
- Arene Ruthenium(II) Complexes as Low-Toxicity Inhibitor against the Proliferation, Migration, and Invasion of MDA-MB-231 Cells through Binding and Stabilizing c-myc G-Quadruplex DNA
- (2016) Qiong Wu et al. ORGANOMETALLICS
- Synthesis, structures, and DNA and protein binding of ruthenium(ii)-p-cymene complexes of substituted pyridylimidazo[1,5-a]pyridine: enhanced cytotoxicity of complexes of ligands appended with a carbazole moiety
- (2016) Themmila Khamrang et al. RSC Advances
- Synthesis, DNA/protein binding, molecular docking, DNA cleavage and in vitro anticancer activity of nickel(ii) bis(thiosemicarbazone) complexes
- (2015) Jebiti Haribabu et al. RSC Advances
- SHELXT– Integrated space-group and crystal-structure determination
- (2015) George M. Sheldrick Acta Crystallographica A-Foundation and Advances
- Crystal structure refinement withSHELXL
- (2015) George M. Sheldrick Acta Crystallographica Section C-Structural Chemistry
- Microwave-assisted synthesis of arene ruthenium(ii) complexes [(η6-RC6H5)Ru(m-MOPIP)Cl]Cl (R = -H and -CH3) as groove binder to c-myc G4 DNA
- (2014) Qiong Wu et al. DALTON TRANSACTIONS
- Arene ruthenium(ii) complex, a potent inhibitor against proliferation, migration and invasion of breast cancer cells, reduces stress fibers, focal adhesions and invadopodia
- (2014) Qiong Wu et al. Metallomics
- Anticancer Ruthenium(η6-p-cymene) Complexes of Nonsteroidal Anti-inflammatory Drug Derivatives
- (2014) Farhana Aman et al. ORGANOMETALLICS
- Recent advances in supramolecular and biological aspects of arene ruthenium(II) complexes
- (2013) Ashish Kumar Singh et al. COORDINATION CHEMISTRY REVIEWS
- Quinolones and non-steroidal anti-inflammatory drugs interacting with copper(ii), nickel(ii), cobalt(ii) and zinc(ii): structural features, biological evaluation and perspectives
- (2013) George Psomas et al. DALTON TRANSACTIONS
- New ruthenium(ii) arene complexes of anthracenyl-appended diazacycloalkanes: effect of ligand intercalation and hydrophobicity on DNA and protein binding and cleavage and cytotoxicity
- (2013) Mani Ganeshpandian et al. DALTON TRANSACTIONS
- DNA Binding and Anti-Cancer Activity of Redox-Active Heteroleptic Piano-Stool Ru(II), Rh(III), and Ir(III) Complexes Containing 4-(2-Methoxypyridyl)phenyldipyrromethene
- (2013) Rakesh Kumar Gupta et al. INORGANIC CHEMISTRY
- Metformin, at Concentrations Corresponding to the Treatment of Diabetes, Potentiates the Cytotoxic Effects of Carboplatin in Cultures of Ovarian Cancer Cells
- (2013) Rafaela Erices et al. Reproductive Sciences
- Structural and immunologic characterization of bovine, horse, and rabbit serum albumins
- (2012) Karolina A. Majorek et al. MOLECULAR IMMUNOLOGY
- Photoactivatable Organometallic Pyridyl Ruthenium(II) Arene Complexes
- (2012) Soledad Betanzos-Lara et al. ORGANOMETALLICS
- Synthesis and Biological Evaluation of the Thionated Antibacterial Agent Nalidixic Acid and Its Organoruthenium(II) Complex
- (2012) Rosana Hudej et al. ORGANOMETALLICS
- Effect of N(4)-Phenyl Substitution in 2-Oxo-1,2-dihydroquinoline-3-carbaldehyde Semicarbazones on the Structure, DNA/Protein Interaction, and Antioxidative and Cytotoxic Activity of Cu(II) Complexes
- (2011) Duraisamy Senthil Raja et al. INORGANIC CHEMISTRY
- Ruthenium(II) complexes: structure, DNA-binding, photocleavage, antioxidant activity, and theoretical studies
- (2011) Xian-Lan Hong et al. JOURNAL OF COORDINATION CHEMISTRY
- Organometallic Ruthenium(II) Arene Compounds with Antiangiogenic Activity
- (2011) Patrycja Nowak-Sliwinska et al. JOURNAL OF MEDICINAL CHEMISTRY
- Physicochemical Studies and Anticancer Potency of Ruthenium η6-p-Cymene Complexes Containing Antibacterial Quinolones
- (2011) Jakob Kljun et al. ORGANOMETALLICS
- Organometallic Anticancer Compounds
- (2010) Gilles Gasser et al. JOURNAL OF MEDICINAL CHEMISTRY
- Exploring Hydrophobic Subdomain IIA of the Protein Bovine Serum Albumin in the Native, Intermediate, Unfolded, and Refolded States by a Small Fluorescence Molecular Reporter
- (2010) Bijan Kumar Paul et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Metformin Selectively Targets Cancer Stem Cells, and Acts Together with Chemotherapy to Block Tumor Growth and Prolong Remission
- (2009) H. A. Hirsch et al. CANCER RESEARCH
- Copper-related diseases: From chemistry to molecular pathology
- (2009) Guido Crisponi et al. COORDINATION CHEMISTRY REVIEWS
- Metformin Associated With Lower Cancer Mortality in Type 2 Diabetes: ZODIAC-16
- (2009) G. W.D. Landman et al. DIABETES CARE
- Tuning heavy metal compounds for anti-tumor activity: is diversity the key to ruthenium’s success?
- (2009) Simon M Page et al. Future Medicinal Chemistry
- OLEX2: a complete structure solution, refinement and analysis program
- (2009) Oleg V. Dolomanov et al. JOURNAL OF APPLIED CRYSTALLOGRAPHY
- [Ru(phen)2(dppz)]2+ as an efficient optical probe for staining nuclear components
- (2009) Venugopal Rajendiran et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Interaction of Bovine Serum Albumin with Dipolar Molecules: Fluorescence and Molecular Docking Studies
- (2009) Bhaswati Bhattacharya et al. JOURNAL OF PHYSICAL CHEMISTRY B
- KP1019, A New Redox-Active Anticancer Agent - Preclinical Development and Results of a Clinical Phase I Study in Tumor Patients
- (2008) Christian G. Hartinger et al. CHEMISTRY & BIODIVERSITY
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- (2008) Venugopal Rajendiran et al. DALTON TRANSACTIONS
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- (2008) Anthony J. Windebank et al. JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM
- Mixed ligand ruthenium(ii) complexes of bis(pyrid-2-yl)-/bis(benzimidazol-2-yl)-dithioether and diimines: Study of non-covalent DNA binding and cytotoxicity
- (2007) Venugopal Rajendiran et al. DALTON TRANSACTIONS
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- (2007) Caiping Tan et al. JOURNAL OF INORGANIC BIOCHEMISTRY
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