Water soluble Ru(ii)–arene complexes of the antidiabetic drug metformin: DNA and protein binding, molecular docking, cytotoxicity and apoptosis-inducing activity

DNA and protein binding, double-strand DNA cleavage and cytotoxicity of mixed ligand copper(II) complexes of the antibacterial drug nalidixic acid

(2017) Rangasamy Loganathan et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Heteroleptic arene Ru(ii) dipyrrinato complexes: DNA, protein binding and anti-cancer activity against the ACHN cancer cell line

(2016) Rakesh Kumar Gupta et al.   DALTON TRANSACTIONS

Antiproliferative activity of ruthenium(ii) arene complexes with mono- and bidentate pyridine-based ligands

(2016) Stefan Richter et al.   DALTON TRANSACTIONS

CF3 Derivatives of the Anticancer Ru(III) Complexes KP1019, NKP-1339, and Their Imidazole and Pyridine Analogues Show Enhanced Lipophilicity, Albumin Interactions, and Cytotoxicity

(2016) Stephanie. W. Chang et al.   INORGANIC CHEMISTRY

Nonsteroidal Anti-inflammatory—Organometallic Anticancer Compounds

(2016) Emilia Păunescu et al.   INORGANIC CHEMISTRY

Arene Ruthenium(II) Complexes as Low-Toxicity Inhibitor against the Proliferation, Migration, and Invasion of MDA-MB-231 Cells through Binding and Stabilizing c-myc G-Quadruplex DNA

(2016) Qiong Wu et al.   ORGANOMETALLICS

Synthesis, structures, and DNA and protein binding of ruthenium(ii)-p-cymene complexes of substituted pyridylimidazo[1,5-a]pyridine: enhanced cytotoxicity of complexes of ligands appended with a carbazole moiety

(2016) Themmila Khamrang et al.   RSC Advances

Synthesis, DNA/protein binding, molecular docking, DNA cleavage and in vitro anticancer activity of nickel(ii) bis(thiosemicarbazone) complexes

(2015) Jebiti Haribabu et al.   RSC Advances

SHELXT– Integrated space-group and crystal-structure determination

(2015) George M. Sheldrick   Acta Crystallographica A-Foundation and Advances

Crystal structure refinement withSHELXL

(2015) George M. Sheldrick   Acta Crystallographica Section C-Structural Chemistry

Microwave-assisted synthesis of arene ruthenium(ii) complexes [(η6-RC6H5)Ru(m-MOPIP)Cl]Cl (R = -H and -CH3) as groove binder to c-myc G4 DNA

(2014) Qiong Wu et al.   DALTON TRANSACTIONS

Arene ruthenium(ii) complex, a potent inhibitor against proliferation, migration and invasion of breast cancer cells, reduces stress fibers, focal adhesions and invadopodia

(2014) Qiong Wu et al.   Metallomics

Anticancer Ruthenium(η6-p-cymene) Complexes of Nonsteroidal Anti-inflammatory Drug Derivatives

(2014) Farhana Aman et al.   ORGANOMETALLICS

Recent advances in supramolecular and biological aspects of arene ruthenium(II) complexes

(2013) Ashish Kumar Singh et al.   COORDINATION CHEMISTRY REVIEWS

Quinolones and non-steroidal anti-inflammatory drugs interacting with copper(ii), nickel(ii), cobalt(ii) and zinc(ii): structural features, biological evaluation and perspectives

(2013) George Psomas et al.   DALTON TRANSACTIONS

New ruthenium(ii) arene complexes of anthracenyl-appended diazacycloalkanes: effect of ligand intercalation and hydrophobicity on DNA and protein binding and cleavage and cytotoxicity

(2013) Mani Ganeshpandian et al.   DALTON TRANSACTIONS

DNA Binding and Anti-Cancer Activity of Redox-Active Heteroleptic Piano-Stool Ru(II), Rh(III), and Ir(III) Complexes Containing 4-(2-Methoxypyridyl)phenyldipyrromethene

(2013) Rakesh Kumar Gupta et al.   INORGANIC CHEMISTRY

Metformin, at Concentrations Corresponding to the Treatment of Diabetes, Potentiates the Cytotoxic Effects of Carboplatin in Cultures of Ovarian Cancer Cells

(2013) Rafaela Erices et al.   Reproductive Sciences

Structural and immunologic characterization of bovine, horse, and rabbit serum albumins

(2012) Karolina A. Majorek et al.   MOLECULAR IMMUNOLOGY

Photoactivatable Organometallic Pyridyl Ruthenium(II) Arene Complexes

(2012) Soledad Betanzos-Lara et al.   ORGANOMETALLICS

Synthesis and Biological Evaluation of the Thionated Antibacterial Agent Nalidixic Acid and Its Organoruthenium(II) Complex

(2012) Rosana Hudej et al.   ORGANOMETALLICS

Effect of N(4)-Phenyl Substitution in 2-Oxo-1,2-dihydroquinoline-3-carbaldehyde Semicarbazones on the Structure, DNA/Protein Interaction, and Antioxidative and Cytotoxic Activity of Cu(II) Complexes

(2011) Duraisamy Senthil Raja et al.   INORGANIC CHEMISTRY

Ruthenium(II) complexes: structure, DNA-binding, photocleavage, antioxidant activity, and theoretical studies

(2011) Xian-Lan Hong et al.   JOURNAL OF COORDINATION CHEMISTRY

Organometallic Ruthenium(II) Arene Compounds with Antiangiogenic Activity

(2011) Patrycja Nowak-Sliwinska et al.   JOURNAL OF MEDICINAL CHEMISTRY

Physicochemical Studies and Anticancer Potency of Ruthenium η6-p-Cymene Complexes Containing Antibacterial Quinolones

(2011) Jakob Kljun et al.   ORGANOMETALLICS

Organometallic Anticancer Compounds

(2010) Gilles Gasser et al.   JOURNAL OF MEDICINAL CHEMISTRY

Exploring Hydrophobic Subdomain IIA of the Protein Bovine Serum Albumin in the Native, Intermediate, Unfolded, and Refolded States by a Small Fluorescence Molecular Reporter

(2010) Bijan Kumar Paul et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Metformin Selectively Targets Cancer Stem Cells, and Acts Together with Chemotherapy to Block Tumor Growth and Prolong Remission

(2009) H. A. Hirsch et al.   CANCER RESEARCH

Copper-related diseases: From chemistry to molecular pathology

(2009) Guido Crisponi et al.   COORDINATION CHEMISTRY REVIEWS

Metformin Associated With Lower Cancer Mortality in Type 2 Diabetes: ZODIAC-16

(2009) G. W.D. Landman et al.   DIABETES CARE

Tuning heavy metal compounds for anti-tumor activity: is diversity the key to ruthenium’s success?

(2009) Simon M Page et al.   Future Medicinal Chemistry

OLEX2: a complete structure solution, refinement and analysis program

(2009) Oleg V. Dolomanov et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

[Ru(phen)2(dppz)]2+ as an efficient optical probe for staining nuclear components

(2009) Venugopal Rajendiran et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Interaction of Bovine Serum Albumin with Dipolar Molecules: Fluorescence and Molecular Docking Studies

(2009) Bhaswati Bhattacharya et al.   JOURNAL OF PHYSICAL CHEMISTRY B

KP1019, A New Redox-Active Anticancer Agent - Preclinical Development and Results of a Clinical Phase I Study in Tumor Patients

(2008) Christian G. Hartinger et al.   CHEMISTRY & BIODIVERSITY

Non-covalent DNA binding and cytotoxicity of certain mixed-ligand ruthenium(ii) complexes of 2,2′-dipyridylamine and diimines

(2008) Venugopal Rajendiran et al.   DALTON TRANSACTIONS

Emerging Protein Targets for Anticancer Metallodrugs: Inhibition of Thioredoxin Reductase and Cathepsin B by Antitumor Ruthenium(II)−Arene Compounds

(2008) Angela Casini et al.   JOURNAL OF MEDICINAL CHEMISTRY

Chemotherapy-induced neuropathy

(2008) Anthony J. Windebank et al.   JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM

Mixed ligand ruthenium(ii) complexes of bis(pyrid-2-yl)-/bis(benzimidazol-2-yl)-dithioether and diimines: Study of non-covalent DNA binding and cytotoxicity

(2007) Venugopal Rajendiran et al.   DALTON TRANSACTIONS

Differences in structure, physiological stability, electrochemistry, cytotoxicity, DNA and protein binding properties between two Ru(III) complexes

(2007) Caiping Tan et al.   JOURNAL OF INORGANIC BIOCHEMISTRY