Choline Supplementation Normalizes Fetal Adiposity and Reduces Lipogenic Gene Expression in a Mouse Model of Maternal Obesity

Activation of AMP-Activated Protein Kinase by 5-Aminoimidazole-4-Carboxamide-1-β-D-Ribonucleoside Prevents Leucine-Stimulated Protein Synthesis in Rat Skeletal Muscle

(2018) Anne M. Pruznak et al.   JOURNAL OF NUTRITION

Choline prevents fetal overgrowth and normalizes placental fatty acid and glucose metabolism in a mouse model of maternal obesity

(2017) Juha Nam et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Obesity and pregnancy: mechanisms of short term and long term adverse consequences for mother and child

(2017) Patrick M Catalano et al.   BMJ-British Medical Journal

Obesity and pregnancy: mechanisms of short term and long term adverse consequences for mother and child

(2017) Patrick M Catalano et al.   BMJ-British Medical Journal

Enhanced offspring predisposition to steatohepatitis with maternal high-fat diet is associated with epigenetic and microbiome alterations

(2017) Umesh D. Wankhade et al.   PLoS One

Gestational Diabetes Mellitus and Macrosomia: A Literature Review

(2015) Kamana KC et al.   ANNALS OF NUTRITION AND METABOLISM

Liver X Receptor Activation Promotes Polyunsaturated Fatty Acid Synthesis in Macrophages: Relevance in the Context of Atherosclerosis

(2015) A. Varin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Maternal High-Fat Feeding Increases Placental Lipoprotein Lipase Activity by Reducing SIRT1 Expression in Mice

(2015) Liping Qiao et al.   DIABETES

Maternal dietary betaine supplementation modifies hepatic expression of cholesterol metabolic genes via epigenetic mechanisms in newborn piglets

(2014) Demin Cai et al.   BRITISH JOURNAL OF NUTRITION

Binding of polyunsaturated fatty acids to LXRαand modulation of SREBP-1 interaction with a specific SCD1 promoter element

(2014) Mariella Caputo et al.   CELL BIOCHEMISTRY AND FUNCTION

DNA Methylation in an Enhancer Region of the FADS Cluster Is Associated with FADS Activity in Human Liver

(2014) Timothy D. Howard et al.   PLoS One

Choline Inadequacy Impairs Trophoblast Function and Vascularization in Cultured Human Placental Trophoblasts

(2013) Xinyin Jiang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Maternal choline intake modulates maternal and fetal biomarkers of choline metabolism in humans

(2012) Jian Yan et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Metabolic crosstalk between choline/1-carbon metabolism and energy homeostasis

(2012) Steven H. Zeisel   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

A higher maternal choline intake among third-trimester pregnant women lowers placental and circulating concentrations of the antiangiogenic factor fms-like tyrosine kinase-1 (sFLT1)

(2012) Xinyin Jiang et al.   FASEB JOURNAL

Dietary supplementation with methyl donors reduces fatty liver and modifies the fatty acid synthase DNA methylation profile in rats fed an obesogenic diet

(2012) P. Cordero et al.   Genes and Nutrition

Mouse Betaine-HomocysteineS-Methyltransferase Deficiency Reduces Body Fat via Increasing Energy Expenditure and Impairing Lipid Synthesis and Enhancing Glucose Oxidation in White Adipose Tissue

(2012) Ya-Wen Teng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetic Ancestry-Smoking Interactions and Lung Function in African Americans: A Cohort Study

(2012) Melinda C. Aldrich et al.   PLoS One

Higher infant body fat with excessive gestational weight gain in overweight women

(2011) Holly R. Hull et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

A Conserved SREBP-1/Phosphatidylcholine Feedback Circuit Regulates Lipogenesis in Metazoans

(2011) Amy K. Walker et al.   CELL

Choline metabolism provides novel insights into nonalcoholic fatty liver disease and its progression

(2011) Karen D. Corbin et al.   CURRENT OPINION IN GASTROENTEROLOGY

Protein and folic acid content in the maternal diet determine lipid metabolism and response to high-fat feeding in rat progeny in an age-dependent manner

(2011) Agata Chmurzynska et al.   Genes and Nutrition

Folate Intake, Mthfr Genotype, and Sex Modulate Choline Metabolism in Mice

(2011) Tina W. Chew et al.   JOURNAL OF NUTRITION

A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects

(2011) Jae Man Lee et al.   NATURE

Betaine improved adipose tissue function in mice fed a high-fat diet: a mechanism for hepatoprotective effect of betaine in nonalcoholic fatty liver disease

(2010) Zhigang Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Hormonal Regulation of Acetyl-CoA Carboxylase Isoenzyme Gene Transcription

(2010) Li Feng ZHAO et al.   ENDOCRINE JOURNAL

Pre- and Postnatal Health: Evidence of Increased Choline Needs

(2010) Marie A. Caudill   JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION

Animal models of nonalcoholic fatty liver disease

(2010) Lionel Hebbard et al.   Nature Reviews Gastroenterology & Hepatology

Neonatal Macrosomia Is an Independent Risk Factor for Adult Metabolic Syndrome

(2010) Gregory M. Hermann et al.   Neonatology

Glycated Hemoglobin, Diabetes, and Cardiovascular Risk in Nondiabetic Adults

(2010)   NEW ENGLAND JOURNAL OF MEDICINE

Expression of the peroxisome proliferator activated receptor gamma gene is repressed by DNA methylation in visceral adipose tissue of mouse models of diabetes

(2009) Katsunori Fujiki et al.   BMC BIOLOGY

Identification of a Physiologically Relevant Endogenous Ligand for PPARα in Liver

(2009) Manu V. Chakravarthy et al.   CELL

Fetal macrosomia and adolescence obesity: results from a longitudinal cohort study

(2009) Y Wang et al.   INTERNATIONAL JOURNAL OF OBESITY

Long chain fatty acids and dietary fats in fetal nutrition

(2009) Irene Cetin et al.   JOURNAL OF PHYSIOLOGY-LONDON

High Fat Feeding Induces Hepatic Fatty Acid Elongation in Mice

(2009) Maaike H. Oosterveer et al.   PLoS One

The glucose-responsive transcription factor ChREBP contributes to glucose-dependent anabolic synthesis and cell proliferation

(2009) X. Tong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of hepatic fatty acid elongase 5 by LXRα–SREBP-1c

(2008) Yan Qin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS