Mouse Betaine-HomocysteineS-Methyltransferase Deficiency Reduces Body Fat via Increasing Energy Expenditure and Impairing Lipid Synthesis and Enhancing Glucose Oxidation in White Adipose Tissue

Thiazolidinediones Are Potent Inducers of Fibroblast Growth Factor 21 Expression in the Liver

(2011) Katsutaka Oishi et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Elevated hepatic fatty acid oxidation, high plasma fibroblast growth factor 21, and fasting bile acids in nonalcoholic steatohepatitis

(2011) Srinivasan Dasarathy et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Lowering Bile Acid Pool Size with a Synthetic Farnesoid X Receptor (FXR) Agonist Induces Obesity and Diabetes through Reduced Energy Expenditure

(2011) Mitsuhiro Watanabe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deletion of Betaine-HomocysteineS-Methyltransferase in Mice Perturbs Choline and 1-Carbon Metabolism, Resulting in Fatty Liver and Hepatocellular Carcinomas

(2011) Ya-Wen Teng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mouse Cardiac Acyl Coenzyme A Synthetase 1 Deficiency Impairs Fatty Acid Oxidation and Induces Cardiac Hypertrophy

(2011) J. M. Ellis et al.   MOLECULAR AND CELLULAR BIOLOGY

The effects of fibroblast growth factor-21 knockdown and over-expression on its signaling pathway and glucose–lipid metabolism in vitro

(2011) Ke Li et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Betaine improved adipose tissue function in mice fed a high-fat diet: a mechanism for hepatoprotective effect of betaine in nonalcoholic fatty liver disease

(2010) Zhigang Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Thyroid Hormone Regulates Hepatic Expression of Fibroblast Growth Factor 21 in aPPARα-dependent Manner

(2010) Andrew C. Adams et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Impairedde NovoCholine Synthesis Explains Why PhosphatidylethanolamineN-Methyltransferase-deficient Mice Are Protected from Diet-induced Obesity

(2010) René L. Jacobs et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Integrated, Nontargeted Ultrahigh Performance Liquid Chromatography/Electrospray Ionization Tandem Mass Spectrometry Platform for the Identification and Relative Quantification of the Small-Molecule Complement of Biological Systems

(2009) Anne M. Evans et al.   ANALYTICAL CHEMISTRY

CRTC2 (TORC2) Contributes to the Transcriptional Response to Fasting in the Liver but Is Not Required for the Maintenance of Glucose Homeostasis

(2009) John Le Lay et al.   Cell Metabolism

Response to Carbohydrate and Fat Refeeding in the Expression of Genes Involved in Nutrient Partitioning and Metabolism: Striking Effects on Fibroblast Growth Factor-21 Induction

(2009) J. Sánchez et al.   ENDOCRINOLOGY

Glucose induces FGF21 mRNA expression through ChREBP activation in rat hepatocytes

(2009) Katsumi Iizuka et al.   FEBS LETTERS

Liver-specific Loss of Long Chain Acyl-CoA Synthetase-1 Decreases Triacylglycerol Synthesis and β-Oxidation and Alters Phospholipid Fatty Acid Composition

(2009) Lei O. Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AdPLA ablation increases lipolysis and prevents obesity induced by high-fat feeding or leptin deficiency

(2009) Kathy Jaworski et al.   NATURE MEDICINE

Subcutaneous Fat Shows Higher Thyroid Hormone Receptor-α1 Gene Expression Than Omental Fat

(2009) Francisco J. Ortega et al.   Obesity

Discovery of Metabolomics Biomarkers for Early Detection of Nephrotoxicity

(2009) Kurt J. Boudonck et al.   TOXICOLOGIC PATHOLOGY

Effect of Transgenic Extrahepatic Expression of Betaine-Homocysteine Methyltransferase on Alcohol or Homocysteine-Induced Fatty Liver

(2008) Cheng Ji et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Beneficial Effects of Subcutaneous Fat Transplantation on Metabolism

(2008) Thien T. Tran et al.   Cell Metabolism

Fibroblast Growth Factor 21 Reverses Hepatic Steatosis, Increases Energy Expenditure, and Improves Insulin Sensitivity in Diet-Induced Obese Mice

(2008) J. Xu et al.   DIABETES

Fibroblast Growth Factor 21 Corrects Obesity in Mice

(2008) Tamer Coskun et al.   ENDOCRINOLOGY

Betaine-HomocysteineS-Methyltransferase-2 Is anS-Methylmethionine-Homocysteine Methyltransferase

(2008) Sandra S. Szegedi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Analysis of the adult human plasma metabolome

(2008) Kay A Lawton et al.   PHARMACOGENOMICS