Binding of polyunsaturated fatty acids to LXRαand modulation of SREBP-1 interaction with a specific SCD1 promoter element

Liver X receptor activation increases hepatic fatty acid desaturation by the induction of SCD1 expression through an LXRα-SREBP1c-dependent mechanism (肝X受体活化可通过LXRα-SREBP1c依赖的机制诱导SCD1表达来增加肝脏脂肪酸不饱和度)

(2013) Xiaoyan Zhang et al.   Journal of Diabetes

Natural Iminosugar (+)-Lentiginosine Inhibits ATPase and Chaperone Activity of Hsp90

(2012) Fabrizio Dal Piaz et al.   PLoS One

Specialized proresolving mediator targets for RvE1 and RvD1 in peripheral blood and mechanisms of resolution

(2011) Gabrielle Fredman et al.   BIOCHEMICAL JOURNAL

Human SREBP1c Expression in Liver Is Directly Regulated by Peroxisome Proliferator-activated Receptor α (PPARα)

(2011) Ana Fernández-Alvarez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Non-esterified polyunsaturated fatty acids distinctly modulate the mitochondrial and cellular ROS production in normoxia and hypoxia

(2011) Peter Schönfeld et al.   JOURNAL OF NEUROCHEMISTRY

An allostatic control of membrane lipid composition by SREBP1

(2010) Rachel M. Hagen et al.   FEBS LETTERS

Polyunsaturated Fatty Acids Selectively Suppress Sterol Regulatory Element-binding Protein-1 through Proteolytic Processing and Autoloop Regulatory Circuit

(2010) Yoshinori Takeuchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selective regulation of UGT1A1 and SREBP-1c mRNA expression by docosahexaenoic, eicosapentaenoic, and arachidonic acids

(2010) Mariella Caputo et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Protein kinase Cbeta mediates hepatic induction of sterol-regulatory element binding protein-1c by insulin

(2010) Takashi Yamamoto et al.   JOURNAL OF LIPID RESEARCH

Insulin Enhances the Biogenesis of Nuclear Sterol Regulatory Element-binding Protein (SREBP)-1c by Posttranscriptional Down-regulation of Insig-2A and Its Dissociation from SREBP Cleavage-activating Protein (SCAP)·SREBP-1c Complex

(2009) Chandrahasa R. Yellaturu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sesterterpenes as Tubulin Tyrosine Ligase Inhibitors. First Insight of Structure−Activity Relationships and Discovery of New Lead

(2009) Fabrizio Dal Piaz et al.   JOURNAL OF MEDICINAL CHEMISTRY

Despite Antiatherogenic Metabolic Characteristics, SCD1-Deficient Mice Have Increased Inflammation and Atherosclerosis

(2008) Marcia L.E. MacDonald et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Docosahexaenoic acid (DHA) and hepatic gene transcription

(2008) Donald B. Jump et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Role of stearoyl-coenzyme A desaturase in regulating lipid metabolism

(2008) Matthew T Flowers et al.   CURRENT OPINION IN LIPIDOLOGY

Cooperation of docosahexaenoic acid and vitamin E in the regulation of UDP-glucuronosyltransferase mRNA expression

(2008) Mariella Caputo et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Regulation of fatty acid synthesis and Δ9-desaturation in senescence of human fibroblasts

(2008) Miho Maeda et al.   LIFE SCIENCES

Dietary fatty acids and cardiovascular disease: An epidemiological approach

(2008) Arja Erkkilä et al.   PROGRESS IN LIPID RESEARCH

The opposing effects of n−3 and n−6 fatty acids

(2007) Gerd Schmitz et al.   PROGRESS IN LIPID RESEARCH