A Review of Recruitment, Adherence and Drop-Out Rates in Omega-3 Polyunsaturated Fatty Acid Supplementation Trials in Children and Adolescents

Correlation between changes in blood fatty acid composition and visual sustained attention performance in children with inattention: effect of dietary n−3 fatty acids containing phospholipids

(2018) Nachum Vaisman et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Omega-3 fatty acid treatment of children with attention-deficit hyperactivity disorder: A randomized, double-blind, placebo-controlled study

(2017) Stacey Ageranioti Bélanger et al.   Paediatrics & Child Health

The effect of omega-3 polyunsaturated fatty acid supplementation on emotional dysregulation, oppositional behaviour and conduct problems in ADHD: A systematic review and meta-analysis

(2016) Ruth E Cooper et al.   JOURNAL OF AFFECTIVE DISORDERS

Efficacy of Polyunsaturated Fatty Acids (PUFA) in the Treatment of Attention Deficit Hyperactivity Disorder

(2016) Marzieh Assareh et al.   Journal of Attention Disorders

Omega 3/6 fatty acids for reading in children: a randomized, double-blind, placebo-controlled trial in 9-year-old mainstream schoolchildren in Sweden

(2016) Mats Johnson et al.   JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY

Paying for antiretroviral adherence: is it unethical when the patient is an adolescent?

(2016) Justin Healy et al.   JOURNAL OF MEDICAL ETHICS

Rates of attrition, non-compliance and missingness in randomized controlled trials of child physical activity interventions using accelerometers: A brief methodological review

(2016) Erin K. Howie et al.   JOURNAL OF SCIENCE AND MEDICINE IN SPORT

The effect of omega-3 fatty acids on aggression: A meta-analysis

(2016) Jamie M. Gajos et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

ω-3 fatty acids as an adjuvant therapy ameliorates methotrexate-induced hepatotoxicity in children and adolescents with acute lymphoblastic leukemia: A randomized placebo-controlled study

(2016) Nancy Samir Elbarbary et al.   NUTRITION

Iron and a mixture of DHA and EPA supplementation, alone and in combination, affect bioactive lipid signalling and morbidity of iron deficient South African school children in a two-by-two randomised controlled trial

(2016) L. Malan et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Reduced inattention and hyperactivity and improved cognition after marine oil extract (PCSO-524®) supplementation in children and adolescents with clinical and subclinical symptoms of attention-deficit hyperactivity disorder (ADHD): a randomised, double-blind, placebo-controlled trial

(2016) James D. Kean et al.   PSYCHOPHARMACOLOGY

Compliance with Sport Injury Prevention Interventions in Randomised Controlled Trials: A Systematic Review

(2016) Miriam van Reijen et al.   SPORTS MEDICINE

Identifying the participant characteristics that predict recruitment and retention of participants to randomised controlled trials involving children: a systematic review

(2016) Louise Robinson et al.   Trials

Nutrition in Pediatric Inflammatory Bowel Disease: From Etiology to Treatment. A Systematic Review

(2016) Francesca Penagini et al.   Nutrients

A protocol for a randomised controlled trial investigating the effect of increasing Omega-3 index with krill oil supplementation on learning, cognition, behaviour and visual processing in typically developing adolescents

(2016) I S M van der Wurff et al.   BMJ Open

A randomised double-blind placebo-controlled trial investigating the behavioural effects of vitamin, mineral and n-3 fatty acid supplementation in typically developing adolescent schoolchildren

(2015) Jonathan D. Tammam et al.   BRITISH JOURNAL OF NUTRITION

Omega 3 polyunsaturated fatty acids and the treatment of depression

(2015) Gelinda Deacon et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Omega-3 Supplementation for Psychotic Mania and Comorbid Anxiety in Children

(2015) Anthony T. Vesco et al.   JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY

Biochemical and Psychological Effects of Omega-3/6 Supplements in Male Adolescents with Attention-Deficit/Hyperactivity Disorder: A Randomized, Placebo-Controlled, Clinical Trial

(2015) Toshiko Matsudaira et al.   JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY

A Randomized Controlled Trial of Individual Family Psychoeducational Psychotherapy and Omega-3 Fatty Acids in Youth with Subsyndromal Bipolar Disorder

(2015) Mary A. Fristad et al.   JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY

Omega-3 Fatty Acids Therapy in Children with Nonalcoholic Fatty Liver Disease: A Randomized Controlled Trial

(2015) Wojciech Janczyk et al.   JOURNAL OF PEDIATRICS

Omega-3 polyunsaturated fatty acid supplementation and cognition: A systematic review and meta-analysis

(2015) Ruth E Cooper et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Reduced Symptoms of Inattention after Dietary Omega-3 Fatty Acid Supplementation in Boys with and without Attention Deficit/Hyperactivity Disorder

(2015) Dienke J Bos et al.   NEUROPSYCHOPHARMACOLOGY

Protective effects of dietary supplementation with natural ω-3 polyunsaturated fatty acids on the visual acuity of school-age children with lower IQ or attention-deficit hyperactivity disorder

(2015) Qiaoling Wu et al.   NUTRITION

A double-blind, placebo-controlled randomized trial to evaluate the efficacy of docosahexaenoic acid supplementation on hepatic fat and associated cardiovascular risk factors in overweight children with nonalcoholic fatty liver disease

(2015) L. Pacifico et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Factors Associated with Clinical Research Recruitment in a Pediatric Academic Medical Center—A Web-Based Survey

(2015) Erica Rose Denhoff et al.   PLoS One

Beneficial effects of ω-3 PUFA in children on cardiovascular risk factors during childhood and adolescence

(2015) Sara Bonafini et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Plasma fatty acid composition in French-Canadian children with non-alcoholic fatty liver disease: Effect of n-3 PUFA supplementation

(2015) S. Spahis et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

A randomized, placebo controlled trial of omega-3 fatty acids in the treatment of young children with autism

(2015) Deepali Mankad et al.   Molecular Autism

Long-Term Treatment with n-3 Polyunsaturated Fatty Acids as a Monotherapy in Children with Nonalcoholic Fatty Liver Disease

(2015) Mehmet Boyraz et al.   Journal of Clinical Research in Pediatric Endocrinology

n–3 Long-chain PUFAs reduce respiratory morbidity caused by iron supplementation in iron-deficient South African schoolchildren: a randomized, double-blind, placebo-controlled intervention

(2015) Linda Malan et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Long-chain n-3 PUFA supplementation decreases physical activity during class time in iron-deficient South African school children

(2014) Cornelius M. Smuts et al.   BRITISH JOURNAL OF NUTRITION

The effect of alpha-linolenic acid supplementation on ADHD symptoms in children: a randomized controlled double-blind study

(2014) Gal Dubnov-Raz et al.   Frontiers in Human Neuroscience

Reduction in behavior problems with omega-3 supplementation in children aged 8-16 years: a randomized, double-blind, placebo-controlled, stratified, parallel-group trial

(2014) Adrian Raine et al.   JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY

A Double-Blind Randomized Trial of Fish Oil to Lower Triglycerides and Improve Cardiometabolic Risk in Adolescents

(2014) Samuel S. Gidding et al.   JOURNAL OF PEDIATRICS

Fatty acids and sleep in UK children: subjective and pilot objective sleep results from the DOLAB study - a randomized controlled trial

(2014) Paul Montgomery et al.   JOURNAL OF SLEEP RESEARCH

Internet-Based, Randomized, Controlled Trial of Omega-3 Fatty Acids for Hyperactivity in Autism

(2014) Stephen Bent et al.   JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY

n-3 LCPUFA improves cognition: The young, the old and the sick

(2014) C. Joffre et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Effect of supplementation with long-chain ω-3 polyunsaturated fatty acids on behavior and cognition in children with attention deficit/hyperactivity disorder (ADHD): A randomized placebo-controlled intervention trial

(2014) Katharina Widenhorn-Müller et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

The Effects of Vitamin E and Omega-3 PUFAs on Endothelial Function among Adolescents with Metabolic Syndrome

(2014) Alireza Ahmadi et al.   Biomed Research International

Omega-3 fatty acids for treatment of non-alcoholic fatty liver disease: design and rationale of randomized controlled trial

(2013) Wojciech Janczyk et al.   BMC Pediatrics

Safety of phosphatidylserine containing omega3 fatty acids in ADHD children: A double-blind placebo-controlled trial followed by an open-label extension

(2013) I. Manor et al.   EUROPEAN PSYCHIATRY

Blood lipids profile in hyperlipidemic children undergoing different dietary long chain polyunsaturated supplementations: a preliminary clinical trial

(2013) Elvira Verduci et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION

Increased Erythrocyte Eicosapentaenoic Acid and Docosahexaenoic Acid Are Associated With Improved Attention and Behavior in Children With ADHD in a Randomized Controlled Three-Way Crossover Trial

(2013) Catherine M. Milte et al.   Journal of Attention Disorders

No differential attrition was found in randomized controlled trials published in general medical journals: a meta-analysis

(2013) Rik Crutzen et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

The I148M Variant of PNPLA3 Reduces the Response to Docosahexaenoic Acid in Children with Non-Alcoholic Fatty Liver Disease

(2013) Valerio Nobili et al.   JOURNAL OF MEDICINAL FOOD

Effects of fish oil supplementation on learning and behaviour of children from Australian Indigenous remote community schools: A randomised controlled trial

(2013) Natalie Parletta et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

An exploratory study of the factors associated with medication nonadherence among youth in adult mental health facilities in Ontario, Canada

(2013) Shannon L. Stewart et al.   PSYCHIATRY RESEARCH

Omega-3 Fatty Acids, Part I

(2013) Stephanie Maxine Ross   Holistic Nursing Practice

The Relationship of Docosahexaenoic Acid (DHA) with Learning and Behavior in Healthy Children: A Review

(2013) Connye Kuratko et al.   Nutrients

Methods to improve recruitment to randomised controlled trials: Cochrane systematic review and meta-analysis

(2013) Shaun Treweek et al.   BMJ Open

Effects of iron and n-3 fatty acid supplementation, alone and in combination, on cognition in school children: a randomized, double-blind, placebo-controlled intervention in South Africa

(2012) Jeannine Baumgartner et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

THE EFFECT OF n-3 LC-PUFA SUPPLEMENTATION ON TENNIS SKILL ACQUISITION IN 10-12 YEAR OLD GIRLS

(2012) FUNDA SEFEROĞLU et al.   BIOLOGY OF SPORT

Reduced medication use and improved pulmonary function with supplements containing vegetable and fruit concentrate, fish oil and probiotics in asthmatic school children: a randomised controlled trial

(2012) Shu-Chen Lee et al.   BRITISH JOURNAL OF NUTRITION

Effects of omega 3 fatty acids supplementation in behavior and non-neurodegenerative neuropsychiatric disorders

(2012) R. M. Ortega et al.   BRITISH JOURNAL OF NUTRITION

Combined ω3 and ω6 Supplementation in Children With Attention-Deficit Hyperactivity Disorder (ADHD) Refractory to Methylphenidate Treatment

(2012) Hemamali Perera et al.   JOURNAL OF CHILD NEUROLOGY

Eicosapentaenoic and docosahexaenoic acids, cognition, and behavior in children with attention-deficit/hyperactivity disorder: A randomized controlled trial

(2012) Catherine M. Milte et al.   NUTRITION

Docosahexaenoic acid for the treatment of fatty liver: Randomised controlled trial in children

(2012) V. Nobili et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Influences of micronutrient and omega-3 fatty acid supplementation on cognition, learning, and behavior: methodological considerations and implications for children and adolescents in developed societies

(2012) Lauren J Frensham et al.   NUTRITION REVIEWS

The effects of n-3 long-chain polyunsaturated fatty acids on bone formation and growth factors in adolescent boys

(2012) Camilla T. Damsgaard et al.   PEDIATRIC RESEARCH

A Double-Blind, Placebo-Controlled Trial of Omega-3 Fatty Acids in Tourette's Disorder

(2012) V. Gabbay et al.   PEDIATRICS

Docosahexaenoic Acid for Reading, Cognition and Behavior in Children Aged 7–9 Years: A Randomized, Controlled Trial (The DOLAB Study)

(2012) Alexandra J. Richardson et al.   PLoS One

A randomized placebo-controlled study on high-dose oral algal docosahexaenoic acid supplementation in children with cystic fibrosis

(2012) G. Alicandro et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Docosahexaenoic acid supplementation decreases liver fat content in children with non-alcoholic fatty liver disease: double-blind randomised controlled clinical trial

(2011) V. Nobili et al.   ARCHIVES OF DISEASE IN CHILDHOOD

Supplementation of n3 Long-chain Polyunsaturated Fatty Acid Synergistically Decreases Insulin Resistance with Weight Loss of Obese Prepubertal and Pubertal Children

(2011) Mardia López-Alarcón et al.   ARCHIVES OF MEDICAL RESEARCH

The effect of phosphatidylserine containing Omega3 fatty-acids on attention-deficit hyperactivity disorder symptoms in children: A double-blind placebo-controlled trial, followed by an open-label extension

(2011) I. Manor et al.   EUROPEAN PSYCHIATRY

Supplementation of N-3 LCPUFA to the Diet of Children Older Than 2 Years: A Commentary by the ESPGHAN Committee on Nutrition

(2011) Carlo Agostoni et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Omega-3 Fatty Acid Supplementation for the Treatment of Children With Attention-Deficit/Hyperactivity Disorder Symptomatology: Systematic Review and Meta-Analysis

(2011) Michael H. Bloch et al.   JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY

Medication Adherence: WHO Cares?

(2011) Marie T. Brown et al.   MAYO CLINIC PROCEEDINGS

EPA supplementation improves teacher-rated behaviour and oppositional symptoms in children with ADHD

(2010) Per A Gustafsson et al.   ACTA PAEDIATRICA

Docosahexaenoic acid supplementation increases prefrontal cortex activation during sustained attention in healthy boys: a placebo-controlled, dose-ranging, functional magnetic resonance imaging study

(2010) Robert K McNamara et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Omega-3 fatty acid supplementation improves vascular function and reduces inflammation in obese adolescents

(2010) Frida Dangardt et al.   ATHEROSCLEROSIS

Randomized, placebo-controlled trial of flax oil in pediatric bipolar disorder

(2010) Barbara L Gracious et al.   BIPOLAR DISORDERS

Impact of a novel nutritional formula on asthma control and biomarkers of allergic airway inflammation in children

(2010) R. Covar et al.   CLINICAL AND EXPERIMENTAL ALLERGY

The Impact of Polyunsaturated Fatty Acids in Reducing Child Attention Deficit and Hyperactivity Disorders

(2010) Catherine Transler et al.   Journal of Attention Disorders

Assessing the impact of attrition in randomized controlled trials

(2010) Catherine E. Hewitt et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

Long-chain Polyunsaturated Fat Supplementation in Children With Low Docosahexaenoic Acid Intakes Alters Immune Phenotypes Compared With Placebo

(2010) VC Mazurak et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Effects of Fish Oil Supplementation on Markers of the Metabolic Syndrome

(2010) Maiken Højgaard Pedersen et al.   JOURNAL OF PEDIATRICS

Do fatty acids help in overcoming reading difficulties? A double-blind, placebo-controlled study of the effects of eicosapentaenoic acid and carnosine supplementation on children with dyslexia

(2009) L. Kairaluoma et al.   CHILD CARE HEALTH AND DEVELOPMENT

The Influence of Short-Chain Essential Fatty Acids on Children with Attention-Deficit/Hyperactivity Disorder: A Double-Blind Placebo-Controlled Study

(2009) Raanan Raz et al.   JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY

Clinical trials: the challenge of recruitment and retention of participants

(2009) Raisa B Gul et al.   JOURNAL OF CLINICAL NURSING

Daily consumption of milk enriched with fish oil, oleic acid, minerals and vitamins reduces cell adhesion molecules in healthy children

(2009) J. Romeo et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Cognitive and mood effects of 8 weeks' supplementation with 400 mg or 1000 mg of the omega-3 essential fatty acid docosahexaenoic acid (DHA) in healthy children aged 10–12 years

(2009) David O. Kennedy et al.   NUTRITIONAL NEUROSCIENCE

A randomised control trial in schoolchildren showed improvement in cognitive function after consuming a bread spread, containing fish flour from a marine source

(2009) Annalien Dalton et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

A review of reporting of participant recruitment and retention in RCTs in six major journals

(2009) Merran Toerien et al.   Trials

Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement

(2009) David Moher et al.   PLOS MEDICINE

How much loss to follow-up is acceptable in long-term randomised trials and prospective studies?

(2008) M. S Fewtrell et al.   ARCHIVES OF DISEASE IN CHILDHOOD

Assessing the Effect of Docosahexaenoic Acid on Cognitive Functions in Healthy, Preschool Children: A Randomized, Placebo-Controlled, Double-Blind Study

(2008) Alan S. Ryan et al.   CLINICAL PEDIATRICS

Clinical research in adolescents: challenges and opportunities using obesity as a model

(2008) K Steinbeck et al.   INTERNATIONAL JOURNAL OF OBESITY

Omega-3/Omega-6 Fatty Acids for Attention Deficit Hyperactivity Disorder

(2008) Mats Johnson et al.   Journal of Attention Disorders

Fish Oil N-3 Polyunsaturated Fatty Acids Selectively Affect Plasma Cytokines and Decrease Illness in Thai Schoolchildren: A Randomized, Double-Blind, Placebo-Controlled Intervention Trial

(2008) Alice Thienprasert et al.   JOURNAL OF PEDIATRICS

Cognitive effects of polyunsaturated fatty acids in children with attention deficit hyperactivity disorder symptoms: A randomised controlled trial

(2008) N. Sinn et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS