Quaternary contact in the initial interaction of CD4 with the HIV-1 envelope trimer

Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G

(2016) Guillaume B.E. Stewart-Jones et al.   CELL

Gctf: Real-time CTF determination and correction

(2016) Kai Zhang   JOURNAL OF STRUCTURAL BIOLOGY

A Highly Conserved gp120 Inner Domain Residue Modulates Env Conformation and Trimer Stability

(2016) Shilei Ding et al.   JOURNAL OF VIROLOGY

Cryo-EM structure of a CD4-bound open HIV-1 envelope trimer reveals structural rearrangements of the gp120 V1V2 loop

(2016) Haoqing Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cryo-EM structure of a native, fully glycosylated, cleaved HIV-1 envelope trimer

(2016) J. H. Lee et al.   SCIENCE

Broadly Neutralizing Antibody 8ANC195 Recognizes Closed and Open States of HIV-1 Env

(2015) Louise Scharf et al.   CELL

Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes

(2015) Steven W. de Taeye et al.   CELL

Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors

(2015) Tongqing Zhou et al.   CELL

Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans

(2015) Fernando Garces et al.   IMMUNITY

Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env

(2015) Young Do Kwon et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env

(2015) Young Do Kwon et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Effects of the I559P gp41 Change on the Conformation and Function of the Human Immunodeficiency Virus (HIV-1) Membrane Envelope Glycoprotein Trimer

(2015) Nirmin Alsahafi et al.   PLoS One

Broad and potent HIV-1 neutralization by a human antibody that binds the gp41–gp120 interface

(2014) Jinghe Huang et al.   NATURE

Structure and immune recognition of trimeric pre-fusion HIV-1 Env

(2014) Marie Pancera et al.   NATURE

Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions

(2014) J. B. Munro et al.   SCIENCE

HIV-1 neutralizing antibodies: understanding nature's pathways

(2013) John R. Mascola et al.   IMMUNOLOGICAL REVIEWS

Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM

(2013) Xueming Li et al.   NATURE METHODS

Delineating Antibody Recognition in Polyclonal Sera from Patterns of HIV-1 Isolate Neutralization

(2013) I. S. Georgiev et al.   SCIENCE

Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer

(2013) J.-P. Julien et al.   SCIENCE

Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer

(2013) D. Lyumkis et al.   SCIENCE

A Next-Generation Cleaved, Soluble HIV-1 Env Trimer, BG505 SOSIP.664 gp140, Expresses Multiple Epitopes for Broadly Neutralizing but Not Non-Neutralizing Antibodies

(2013) Rogier W. Sanders et al.   PLoS Pathogens

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

HIV-1 Neutralizing Antibodies Display Dual Recognition of the Primary and Coreceptor Binding Sites and Preferential Binding to Fully Cleaved Envelope Glycoproteins

(2012) Y. Li et al.   JOURNAL OF VIROLOGY

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

(2011) Jason S. McLellan et al.   NATURE

Broad neutralization coverage of HIV by multiple highly potent antibodies

(2011) Laura M. Walker et al.   NATURE

Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures

(2011) A. Harris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

(2011) X. Wu et al.   SCIENCE

A clustering approach to multireference alignment of single-particle projections in electron microscopy

(2010) C.O.S. Sorzano et al.   JOURNAL OF STRUCTURAL BIOLOGY

Structural Comparison of HIV-1 Envelope Spikes with and without the V1/V2 Loop

(2010) G. Hu et al.   JOURNAL OF VIROLOGY

Topological Layers in the HIV-1 gp120 Inner Domain Regulate gp41 Interaction and CD4-Triggered Conformational Transitions

(2010) Andrés Finzi et al.   MOLECULAR CELL

Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01

(2010) T. Zhou et al.   SCIENCE

ACEMD: Accelerating Biomolecular Dynamics in the Microsecond Time Scale

(2009) M. J. Harvey et al.   Journal of Chemical Theory and Computation

Appion: An integrated, database-driven pipeline to facilitate EM image processing

(2009) Gabriel C. Lander et al.   JOURNAL OF STRUCTURAL BIOLOGY

DoG Picker and TiltPicker: Software tools to facilitate particle selection in single particle electron microscopy

(2009) N.R. Voss et al.   JOURNAL OF STRUCTURAL BIOLOGY

Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility

(2009) M. Pancera et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Broad and Potent Neutralizing Antibodies from an African Donor Reveal a New HIV-1 Vaccine Target

(2009) L. M. Walker et al.   SCIENCE

Molecular architecture of native HIV-1 gp120 trimers

(2008) Jun Liu et al.   NATURE