Phosphoinositide-dependent protein kinase 1 (PDK1) mediates potent inhibitory effects on eosinophils

Prostaglandin E2 Inhibits Eosinophil Trafficking through E-Prostanoid 2 Receptors

(2014) E. M. Sturm et al.   JOURNAL OF IMMUNOLOGY

Functionally Competent Eosinophils Differentiated Ex Vivo in High Purity from Normal Mouse Bone Marrow

(2014) K. D. Dyer et al.   JOURNAL OF IMMUNOLOGY

Chemotaxis of bone marrow derived eosinophils in vivo: A novel method to explore receptor-dependent trafficking in the mouse

(2013) Eva M. Sturm et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

PDK1 decreases TACE-mediated α-secretase activity and promotes disease progression in prion and Alzheimer's diseases

(2013) Mathéa Pietri et al.   NATURE MEDICINE

The Kinase PDK1 Is Essential for B-Cell Receptor Mediated Survival Signaling

(2013) Sung-Gyoo Park et al.   PLoS One

Akt Regulates TNFα Synthesis Downstream of RIP1 Kinase Activation during Necroptosis

(2013) Colleen R. McNamara et al.   PLoS One

The effect of pharmacological PI3Kγ inhibitor on eotaxin-induced human eosinophil functions

(2013) Yukiko Saito et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Loss of Pdk1-Foxo1 Signaling in Myeloid Cells Predisposes to Adipose Tissue Inflammation and Insulin Resistance

(2012) Y. Kawano et al.   DIABETES

Endothelial E-type prostanoid 4 receptors promote barrier function and inhibit neutrophil trafficking

(2012) Viktoria Konya et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

EP4 receptor stimulation down-regulates human eosinophil function

(2011) Petra Luschnig-Schratl et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The Prostaglandin E 2 Receptor EP4 Is Expressed by Human Platelets and Potently Inhibits Platelet Aggregation and Thrombus Formation

(2010) Sonia Philipose et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Characterization of GSK2334470, a novel and highly specific inhibitor of PDK1

(2010) Ayaz Najafov et al.   BIOCHEMICAL JOURNAL

Phosphoinositide-dependent Kinase PDK1 in the Regulation of Ca2+ Entry into Mast Cells

(2010) Ekaterina Shumilina et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Phosphoinositide-Dependent Kinase 1 Provides Negative Feedback Inhibition to Toll-Like Receptor-Mediated NF- B Activation in Macrophages

(2010) B. Chaurasia et al.   MOLECULAR AND CELLULAR BIOLOGY

CRTH2 and D-Type Prostanoid Receptor Antagonists as Novel Therapeutic Agents for Inflammatory Diseases

(2010) Rufina Schuligoi et al.   PHARMACOLOGY

The Akt inhibitor triciribine sensitizes prostate carcinoma cells to TRAIL-induced apoptosis

(2009) Alexandra Dieterle et al.   INTERNATIONAL JOURNAL OF CANCER

PDK1 Regulates Chemotaxis in Human Neutrophils

(2009) M. Yagi et al.   JOURNAL OF DENTAL RESEARCH

The kinase PDK1 integrates T cell antigen receptor and CD28 coreceptor signaling to induce NF-κB and activate T cells

(2009) Sung-Gyoo Park et al.   NATURE IMMUNOLOGY

Differential Involvement of Ca2+ and Actin Filament in Leukocyte Shape Change

(2008) Petra Schratl et al.   PHARMACOLOGY