Characterization of GSK2334470, a novel and highly specific inhibitor of PDK1

Characterization of PF-4708671, a novel and highly specific inhibitor of p70 ribosomal S6 kinase (S6K1)

(2010) Laura R. Pearce et al.   BIOCHEMICAL JOURNAL

New Roles for the LKB1-NUAK Pathway in Controlling Myosin Phosphatase Complexes and Cell Adhesion

(2010) A. Zagorska et al.   Science Signaling

Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR)

(2009) Juan M. García-Martínez et al.   BIOCHEMICAL JOURNAL

AKT-Independent Signaling Downstream of Oncogenic PIK3CA Mutations in Human Cancer

(2009) Krishna M. Vasudevan et al.   CANCER CELL

3-Phosphoinositide-Dependent Kinase 1 Potentiates Upstream Lesions on the Phosphatidylinositol 3-Kinase Pathway in Breast Carcinoma

(2009) M. Maurer et al.   CANCER RESEARCH

Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans

(2009) A. A. Soukas et al.   GENES & DEVELOPMENT

Use of the Pharmacological Inhibitor BX795 to Study the Regulation and Physiological Roles of TBK1 and IκB Kinase ϵ

(2009) Kristopher Clark et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The nuts and bolts of AGC protein kinases

(2009) Laura R. Pearce et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Rictor/TORC2 Regulates Caenorhabditis elegans Fat Storage, Body Size, and Development through sgk-1

(2009) Kevin T Jones et al.   PLOS BIOLOGY

mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1)

(2008) Juan M. García-Martínez et al.   BIOCHEMICAL JOURNAL

New anti-cancer role for PDK1 inhibitors: preventing resistance to tamoxifen

(2008) Christian Peifer et al.   BIOCHEMICAL JOURNAL

Parallel RNAi and compound screens identify the PDK1 pathway as a target for tamoxifen sensitization

(2008) Elizabeth Iorns et al.   BIOCHEMICAL JOURNAL

Small-Molecule Inhibitors of PDK1

(2008) Christian Peifer et al.   ChemMedChem

The Life and Death of Protein Kinase C

(2008) Christine Gould et al.   CURRENT DRUG TARGETS

Analysis of 3-phosphoinositide-dependent kinase-1 signaling and function in ES cells

(2008) Tanja Tamgüney et al.   EXPERIMENTAL CELL RESEARCH

Mutation of the PDK1 PH Domain Inhibits Protein Kinase B/Akt, Leading to Small Size and Insulin Resistance

(2008) J. R. Bayascas et al.   MOLECULAR AND CELLULAR BIOLOGY

The RSK family of kinases: emerging roles in cellular signalling

(2008) Rana Anjum et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY