Transcriptional and Post-Transcriptional Mechanisms of the Development of Neocortical Lamination

Comprehensive transcriptome analysis of neocortical layers in humans, chimpanzees and macaques

(2017) Zhisong He et al.   NATURE NEUROSCIENCE

The doublesex-related Dmrta2 safeguards neural progenitor maintenance involving transcriptional regulation of Hes1

(2017) Fraser I. Young et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neurodevelopmental protein Musashi-1 interacts with the Zika genome and promotes viral replication

(2017) Pavithra L. Chavali et al.   SCIENCE

The Functioning of a Cortex without Layers

(2017) Julien Guy et al.   Frontiers in Neuroanatomy

The RNA-binding protein MARF1 promotes cortical neurogenesis through its RNase activity domain

(2017) Yoshitaka Kanemitsu et al.   Scientific Reports

RNA on the brain: emerging layers of post-transcriptional regulation in cerebral cortex development

(2017) Ashley L. Lennox et al.   Wiley Interdisciplinary Reviews-Developmental Biology

Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex

(2016) Xiaochang Zhang et al.   CELL

Epigenetic regulation by BAF (mSWI/SNF) chromatin remodeling complexes is indispensable for embryonic development

(2016) Huong Nguyen et al.   CELL CYCLE

Zika Virus Infects Human Cortical Neural Progenitors and Attenuates Their Growth

(2016) Hengli Tang et al.   Cell Stem Cell

Cc2d1a Loss of Function Disrupts Functional and Morphological Development in Forebrain Neurons Leading to Cognitive and Social Deficits

(2016) Adam W. Oaks et al.   CEREBRAL CORTEX

Dynamic mRNA Transport and Local Translation in Radial Glial Progenitors of the Developing Brain

(2016) Louis-Jan Pilaz et al.   CURRENT BIOLOGY

Assessing similarity to primary tissue and cortical layer identity in induced pluripotent stem cell-derived cortical neurons through single-cell transcriptomics

(2016) Adam E. Handel et al.   HUMAN MOLECULAR GENETICS

The frontier of RNA metamorphosis and ribosome signature in neocortical development

(2016) Matthew L. Kraushar et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

RNA regulation went wrong in neurodevelopmental disorders: The example of Msi/Elavl RNA binding proteins

(2016) Masato Yano et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Alternative splicing and nonsense-mediated mRNA decay enforce neural specific gene expression

(2016) Sika Zheng   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Long noncoding RNAs: Central to nervous system development

(2016) Ronald P. Hart et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

The Brazilian Zika virus strain causes birth defects in experimental models

(2016) Fernanda R. Cugola et al.   NATURE

Adult mouse cortical cell taxonomy revealed by single cell transcriptomics

(2016) Bosiljka Tasic et al.   NATURE NEUROSCIENCE

Akirin2 is essential for the formation of the cerebral cortex

(2016) Peter J. Bosch et al.   Neural Development

Prolonged Mitosis of Neural Progenitors Alters Cell Fate in the Developing Brain

(2016) Louis-Jan Pilaz et al.   NEURON

A Primate lncRNA Mediates Notch Signaling during Neuronal Development by Sequestering miRNA

(2016) Neha Rani et al.   NEURON

The Cellular and Molecular Landscapes of the Developing Human Central Nervous System

(2016) John C. Silbereis et al.   NEURON

Sequential transcriptional waves direct the differentiation of newborn neurons in the mouse neocortex

(2016) L. Telley et al.   SCIENCE

Zika virus impairs growth in human neurospheres and brain organoids

(2016) P. P. Garcez et al.   SCIENCE

The RNA binding protein HuR determines the differential translation of autism-associated FoxP subfamily members in the developing neocortex

(2016) T. Popovitchenko et al.   Scientific Reports

Intermediate Progenitor Cohorts Differentially Generate Cortical Layers and Require Tbr2 for Timely Acquisition of Neuronal Subtype Identity

(2016) Anca B. Mihalas et al.   Cell Reports

A large fraction of neocortical myelin ensheathes axons of local inhibitory neurons

(2016) Kristina D Micheva et al.   eLife

Multiple markers of cortical morphology reveal evidence of supragranular thinning in schizophrenia

(2016) K Wagstyl et al.   Translational Psychiatry

Identification of long non-coding RNAs involved in neuronal development and intellectual disability

(2016) Eva D’haene et al.   Scientific Reports

Genomic divergence and brain evolution: How regulatory DNA influences development of the cerebral cortex

(2015) Debra L. Silver   BIOESSAYS

Saturated Reconstruction of a Volume of Neocortex

(2015) Narayanan Kasthuri et al.   CELL

Molecular Identity of Human Outer Radial Glia during Cortical Development

(2015) Alex A. Pollen et al.   CELL

Thalamocortical Connections Drive Intracortical Activation of Functional Columns in the MislaminatedReelerSomatosensory Cortex

(2015) Robin J. Wagener et al.   CEREBRAL CORTEX

Autism spectrum disorders: from genes to neurobiology

(2015) A Jeremy Willsey et al.   CURRENT OPINION IN NEUROBIOLOGY

Rbm8a Haploinsufficiency Disrupts Embryonic Cortical Development Resulting in Microcephaly

(2015) H. Mao et al.   JOURNAL OF NEUROSCIENCE

Thalamic WNT3 Secretion Spatiotemporally Regulates the Neocortical Ribosome Signature and mRNA Translation to Specify Neocortical Cell Subtypes

(2015) M. L. Kraushar et al.   JOURNAL OF NEUROSCIENCE

Neural Precursor Lineages Specify Distinct Neocortical Pyramidal Neuron Types

(2015) William A. Tyler et al.   JOURNAL OF NEUROSCIENCE

Molecular mechanisms of epilepsy

(2015) Kevin Staley   NATURE NEUROSCIENCE

Single-cell analysis reveals transcriptional heterogeneity of neural progenitors in human cortex

(2015) Matthew B Johnson et al.   NATURE NEUROSCIENCE

The neocortical circuit: themes and variations

(2015) Kenneth D Harris et al.   NATURE NEUROSCIENCE

The exon junction complex as a node of post-transcriptional networks

(2015) Hervé Le Hir et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Proliferation control in neural stem and progenitor cells

(2015) Catarina C. F. Homem et al.   NATURE REVIEWS NEUROSCIENCE

DeCoN: Genome-wide Analysis of In Vivo Transcriptional Dynamics during Pyramidal Neuron Fate Selection in Neocortex

(2015) Bradley J. Molyneaux et al.   NEURON

Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion

(2015) M. Florio et al.   SCIENCE

Anatomy and physiology of the thick-tufted layer 5 pyramidal neuron

(2015) Srikanth Ramaswamy et al.   Frontiers in Cellular Neuroscience

N-cadherin-based adherens junction regulates the maintenance, proliferation, and differentiation of neural progenitor cells during development

(2015) Yasunori Miyamoto et al.   Cell Adhesion & Migration

Corticofugal GABAergic projection neurons in the mouse frontal cortex

(2015) Ryohei Tomioka et al.   Frontiers in Neuroanatomy

Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development

(2015) Ramanathan Narayanan et al.   Cell Reports

Post-transcriptional regulation in corticogenesis: how RNA-binding proteins help build the brain

(2015) Louis-Jan Pilaz et al.   Wiley Interdisciplinary Reviews-RNA

The Cell Cycle Regulator CCDC6 Is a Key Target of RNA-Binding Protein EWS

(2015) Sujitha Duggimpudi et al.   PLoS One

Deterministic Progenitor Behavior and Unitary Production of Neurons in the Neocortex

(2014) Peng Gao et al.   CELL

Persistence of Functional Sensory Maps in the Absence of Cortical Layers in the Somsatosensory Cortex ofReelerMice

(2014) Julien Guy et al.   CEREBRAL CORTEX

Integrin  v 3 and thyroid hormones promote expansion of progenitors in embryonic neocortex

(2014) D. Stenzel et al.   DEVELOPMENT

Prenatal Deletion of the RNA-Binding Protein HuD Disrupts Postnatal Cortical Circuit Maturation and Behavior

(2014) E. M. DeBoer et al.   JOURNAL OF NEUROSCIENCE

A Class of GABAergic Neurons in the Prefrontal Cortex Sends Long-Range Projections to the Nucleus Accumbens and Elicits Acute Avoidance Behavior

(2014) A. T. Lee et al.   JOURNAL OF NEUROSCIENCE

FMRP regulates multipolar to bipolar transition affecting neuronal migration and cortical circuitry

(2014) Giorgio La Fata et al.   NATURE NEUROSCIENCE

A day in the life of the spliceosome

(2014) A. Gregory Matera et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

An eIF4E1/4E-T Complex Determines the Genesis of Neurons from Precursors by Translationally Repressing a Proneurogenic Transcription Program

(2014) Guang Yang et al.   NEURON

Cell cycle-dependent regulation of the RNA-binding protein Staufen1

(2014) Karine Boulay et al.   NUCLEIC ACIDS RESEARCH

Temporally defined neocortical translation and polysome assembly are determined by the RNA-binding protein Hu antigen R

(2014) M. L. Kraushar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct Profiles of Myelin Distribution Along Single Axons of Pyramidal Neurons in the Neocortex

(2014) G. S. Tomassy et al.   SCIENCE

Direct Conversion of Fibroblasts to Neurons by Reprogramming PTB-Regulated MicroRNA Circuits

(2013) Yuanchao Xue et al.   CELL

BAF chromatin remodeling complex: Cortical size regulation and beyond

(2013) Tran Cong Tuoc et al.   CELL CYCLE

Correlated Gene Expression and Target Specificity Demonstrate Excitatory Projection Neuron Diversity

(2013) Staci A. Sorensen et al.   CEREBRAL CORTEX

Radial glia - from boring cables to stem cell stars

(2013) P. Malatesta et al.   DEVELOPMENT

Chromatin Regulation by BAF170 Controls Cerebral Cortical Size and Thickness

(2013) Tran Cong Tuoc et al.   DEVELOPMENTAL CELL

Mechanisms of cell migration in the nervous system

(2013) Jonathan A. Cooper   JOURNAL OF CELL BIOLOGY

Multiplex Genetic Fate Mapping Reveals a Novel Route of Neocortical Neurogenesis, Which Is Altered in the Ts65Dn Mouse Model of Down Syndrome

(2013) W. A. Tyler et al.   JOURNAL OF NEUROSCIENCE

Molecular logic of neocortical projection neuron specification, development and diversity

(2013) Luciano Custo Greig et al.   NATURE REVIEWS NEUROSCIENCE

Precursor Diversity and Complexity of Lineage Relationships in the Outer Subventricular Zone of the Primate

(2013) Marion Betizeau et al.   NEURON

Post-transcriptional regulatory elements and spatiotemporal specification of neocortical stem cells and projection neurons

(2013) E.M. DeBoer et al.   NEUROSCIENCE

Expression profiling of mouse subplate reveals a dynamic gene network and disease association with autism and schizophrenia

(2013) Anna Hoerder-Suabedissen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-92b regulates the development of intermediate cortical progenitors in embryonic mouse brain

(2013) T. J. Nowakowski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diversity of layer 5 projection neurons in the mouse motor cortex

(2013) Manfred J. Oswald et al.   Frontiers in Cellular Neuroscience

Mosaic Analysis with Double Markers Reveals Cell-Type-Specific Paternal Growth Dominance

(2013) Simon Hippenmeyer et al.   Cell Reports

MicroRNA Cluster miR-17-92 Regulates Neural Stem Cell Expansion and Transition to Intermediate Progenitors in the Developing Mouse Neocortex

(2013) Shan Bian et al.   Cell Reports

Transcriptional co-regulation of neuronal migration and laminar identity in the neocortex

(2012) K. Y. Kwan et al.   DEVELOPMENT

Phosphoregulation of the RNA-binding Protein Hu Antigen R (HuR) by Cdk5 Affects Centrosome Function

(2012) Natalia Filippova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cis-regulatory control of corticospinal system development and evolution

(2012) Sungbo Shim et al.   NATURE

Extensions of MADM (Mosaic Analysis with Double Markers) in Mice

(2012) Bosiljka Tasic et al.   PLoS One

The Mammalian DM Domain Transcription Factor Dmrta2 Is Required for Early Embryonic Development of the Cerebral Cortex

(2012) Daijiro Konno et al.   PLoS One

P-Bodies and Stress Granules: Possible Roles in the Control of Translation and mRNA Degradation

(2012) C. J. Decker et al.   Cold Spring Harbor Perspectives in Biology

Molecular Control of Neurogenesis: A View from the Mammalian Cerebral Cortex

(2012) B. Martynoga et al.   Cold Spring Harbor Perspectives in Biology

Excitatory neuronal connectivity in the barrel cortex

(2012) Dirk Feldmeyer   Frontiers in Neuroanatomy

Neocortical neurogenesis and neuronal migration

(2012) Xin Tan et al.   Wiley Interdisciplinary Reviews-Developmental Biology

SOX2 expression levels distinguish between neural progenitor populations of the developing dorsal telencephalon

(2011) Scott R. Hutton et al.   DEVELOPMENTAL BIOLOGY

Changes in Musashi-1 subcellular localization correlate with cell cycle exit during postnatal retinal development

(2011) P.E.B. Nickerson et al.   EXPERIMENTAL EYE RESEARCH

Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses

(2011) M. N. Cabili et al.   GENES & DEVELOPMENT

FMRP Regulates the Transition from Radial Glial Cells to Intermediate Progenitor Cells during Neocortical Development

(2011) R. Saffary et al.   JOURNAL OF NEUROSCIENCE

Stabilization of Dll1 mRNA by Elavl1/HuR in neuroepithelial cells undergoing mitosis

(2011) Daniel J. García-Domínguez et al.   MOLECULAR BIOLOGY OF THE CELL

Spatio-temporal transcriptome of the human brain

(2011) Hyo Jung Kang et al.   NATURE

The splicing regulator Rbfox1 (A2BP1) controls neuronal excitation in the mammalian brain

(2011) Lauren T Gehman et al.   NATURE GENETICS

A new subtype of progenitor cell in the mouse embryonic neocortex

(2011) Xiaoqun Wang et al.   NATURE NEUROSCIENCE

A Transcriptomic Atlas of Mouse Neocortical Layers

(2011) T. Grant Belgard et al.   NEURON

Reelin Regulates Cadherin Function via Dab1/Rap1 to Control Neuronal Migration and Lamination in the Neocortex

(2011) Santos J. Franco et al.   NEURON

Neural stem and progenitor cells shorten S-phase on commitment to neuron production

(2011) Yoko Arai et al.   Nature Communications

Foxp2 Regulates Gene Networks Implicated in Neurite Outgrowth in the Developing Brain

(2011) Sonja C. Vernes et al.   PLoS Genetics

Cortical Neural Precursors Inhibit Their Own Differentiation via N-Cadherin Maintenance of β-Catenin Signaling

(2010) Jianing Zhang et al.   DEVELOPMENTAL CELL

Heterogeneity in Ventricular Zone Neural Precursors Contributes to Neuronal Fate Diversity in the Postnatal Neocortex

(2010) E. K. Stancik et al.   JOURNAL OF NEUROSCIENCE

miR-375 Inhibits Differentiation of Neurites by Lowering HuD Levels

(2010) K. Abdelmohsen et al.   MOLECULAR AND CELLULAR BIOLOGY

Neurogenic radial glia in the outer subventricular zone of human neocortex

(2010) David V. Hansen et al.   NATURE

The exon junction complex component Magoh controls brain size by regulating neural stem cell division

(2010) Debra L Silver et al.   NATURE NEUROSCIENCE

Nova2 Regulates Neuronal Migration through an RNA Switch in Disabled-1 Signaling

(2010) Masato Yano et al.   NEURON

The Glial Nature of Embryonic and Adult Neural Stem Cells

(2009) Arnold Kriegstein et al.   Annual Review of Neuroscience

Integrating microRNA and mRNA expression profiles of neuronal progenitors to identify regulatory networks underlying the onset of cortical neurogenesis

(2009) Joseph A Nielsen et al.   BMC NEUROSCIENCE

Intermediate Neuronal Progenitors (Basal Progenitors) Produce Pyramidal–Projection Neurons for All Layers of Cerebral Cortex

(2009) Tom Kowalczyk et al.   CEREBRAL CORTEX

Receptor mapping: architecture of the human cerebral cortex

(2009) Karl Zilles et al.   CURRENT OPINION IN NEUROLOGY

The Transition from Radial Glial to Intermediate Progenitor Cell Is Inhibited by FGF Signaling during Corticogenesis

(2009) W. Kang et al.   JOURNAL OF NEUROSCIENCE

Evolution of the neocortex: a perspective from developmental biology

(2009) Pasko Rakic   NATURE REVIEWS NEUROSCIENCE

Fgf10 Regulates Transition Period of Cortical Stem Cell Differentiation to Radial Glia Controlling Generation of Neurons and Basal Progenitors

(2009) Setsuko Sahara et al.   NEURON

CD133 (Prominin) Negative Human Neural Stem Cells Are Clonogenic and Tripotent

(2009) Yirui Sun et al.   PLoS One

The Level of the Transcription Factor Pax6 Is Essential for Controlling the Balance between Neural Stem Cell Self-Renewal and Neurogenesis

(2009) Stephen N. Sansom et al.   PLoS Genetics

Disorders of Cortical Formation: MR Imaging Features

(2008) A.A.K. Abdel Razek et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

The determination of projection neuron identity in the developing cerebral cortex

(2008) Dino P Leone et al.   CURRENT OPINION IN NEUROBIOLOGY

The T-box transcription factor Eomes/Tbr2 regulates neurogenesis in the cortical subventricular zone

(2008) S. J. Arnold et al.   GENES & DEVELOPMENT

Distinct behaviors of neural stem and progenitor cells underlie cortical neurogenesis

(2008) Stephen C. Noctor et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Sam68 Regulates a Set of Alternatively Spliced Exons during Neurogenesis

(2008) G. Chawla et al.   MOLECULAR AND CELLULAR BIOLOGY

An intrinsic mechanism of corticogenesis from embryonic stem cells

(2008) Nicolas Gaspard et al.   NATURE

Interaction between Reelin and Notch Signaling Regulates Neuronal Migration in the Cerebral Cortex

(2008) Kazue Hashimoto-Torii et al.   NEURON

Satb2 Is a Postmitotic Determinant for Upper-Layer Neuron Specification in the Neocortex

(2008) Olga Britanova et al.   NEURON

Satb2 Regulates Callosal Projection Neuron Identity in the Developing Cerebral Cortex

(2008) Elizabeth A. Alcamo et al.   NEURON

Tbr2 Directs Conversion of Radial Glia into Basal Precursors and Guides Neuronal Amplification by Indirect Neurogenesis in the Developing Neocortex

(2008) Alessandro Sessa et al.   NEURON

miR-519 reduces cell proliferation by lowering RNA-binding protein HuR levels

(2008) K. Abdelmohsen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Sox1 to Pax6 Switch Drives Neuroectoderm to Radial Glia Progression During Differentiation of Mouse Embryonic Stem Cells

(2008) David M. Suter et al.   STEM CELLS

Neuroanatomy of autism

(2008) David G. Amaral et al.   TRENDS IN NEUROSCIENCES